chronic myeloid leukemia

Summary
Synonym
  • CML
  • CML - chronic Myelogenous Leukemia
  • Myeloid Leukemia, chronic
  • chronic granulocytic leukaemia
  • chronic granulocytic leukemia
  • chronic myelogenous leukaemia
  • chronic myelogenous leukemia
  • chronic myeloid leukaemia
Definition
A myeloid leukemia that is characterized by over production of white blood cells.
Super Class
myeloid leukemia
Disease Ontology
DOID:8552
Mondo Disease Ontology
UMLS
ORDO
OMIM
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 11 - 20 of 39 in total
Gene ID Gene Symbol Description Source
1244 ABCC2 ATP binding cassette subfamily C member 2
1399 CRKL CRK like proto-oncogene, adaptor protein
1543 CYP1A1 cytochrome P450 family 1 subfamily A member 1
1577 CYP3A5 cytochrome P450 family 3 subfamily A member 5
1636 ACE angiotensin I converting enzyme
1786 DNMT1 DNA methyltransferase 1
1869 E2F1 E2F transcription factor 1
2146 EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
2212 FCGR2A Fc gamma receptor IIa
2261 FGFR3 fibroblast growth factor receptor 3
Displaying entries 21 - 29 of 29 in total
Gene ID Gene Symbol Description Source
18669 Abcb1b ATP-binding cassette, sub-family B member 1B
18671 Abcb1a ATP-binding cassette, sub-family B member 1A
20850 Stat5a signal transducer and activator of transcription 5A
21803 Tgfb1 transforming growth factor, beta 1
21939 Cd40 CD40 antigen
22339 Vegfa vascular endothelial growth factor A
26357 Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group)
59287 Ncstn nicastrin
110279 Bcr BCR activator of RhoGEF and GTPase
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
24179 Agt angiotensinogen
24185 Akt1 AKT serine/threonine kinase 1
24296 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
24310 Ace angiotensin I converting enzyme
25303 Abcc2 ATP binding cassette subfamily C member 2
25325 Il10 interleukin 10
25385 Faslg Fas ligand
29583 Pecam1 platelet and endothelial cell adhesion molecule 1
59086 Tgfb1 transforming growth factor, beta 1
60582 Il1rn interleukin 1 receptor antagonist
Displaying all 8 entries
Gene ID Gene Symbol Description Source
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
36428 Mdr49 Multi drug resistance 49
38726 Mdr65 Multi drug resistance 65
38868 Snmp2 Sensory neuron membrane protein 2
39564 btl breathless
42160 htl heartless
42964 Nct Nicastrin
Displaying all 2 entries
Gene ID Gene Symbol Description Source
30682 vegfaa vascular endothelial growth factor Aa
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Displaying all 4 entries
Gene ID Gene Symbol Description Source Organism
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
399170 akt1.S AKT serine/threonine kinase 1 S homeolog Xenopus laevis (African clawed frog)
399347 fgfr3.S fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog Xenopus laevis (African clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
Displaying all 9 entries
Gene ID Gene Symbol Description Source
172905 aph-2 Nicastrin
176673 scav-3 Sensory neuron membrane protein 2
176787 scav-2 SCAVenger receptor (CD36 family) related
178215 pgp-1 Multidrug resistance protein pgp-1
180289 mrp-7 Multidrug resistance protein mrp-7
180408 mrp-2 Multidrug resistance-associated protein 1
180409 mrp-1 Multidrug resistance-associated protein 1
180780 acn-1 Inactive angiotensin-converting enzyme-related protein
181326 pgp-3 Multidrug resistance protein pgp-3
Displaying all 2 entries
Gene ID Gene Symbol Description Source
850369 ADP1 putative ATP-dependent permease ADP1
853671 STE6 ATP-binding cassette a-factor transporter STE6

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