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Guidelines
MIRAGE
type 2 diabetes mellitus

Summary
Synonym
  • NIDDM
  • insulin resistance
  • non-insulin-dependent diabetes mellitus
  • type 2 diabetes
  • type II diabetes mellitus
Definition
A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Super Class
diabetes mellitus
Disease Ontology
DOID:9352
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 31 - 40 of 129 in total
Gene ID Gene Symbol Description Source
2155 F7 coagulation factor VII
2475 MTOR mechanistic target of rapamycin kinase
2642 GCGR glucagon receptor
2645 GCK glucokinase
2690 GHR growth hormone receptor
2739 GLO1 glyoxalase I
2820 GPD2 glycerol-3-phosphate dehydrogenase 2
2864 FFAR1 free fatty acid receptor 1
2878 GPX3 glutathione peroxidase 3
3077 HFE homeostatic iron regulator
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
11652 Akt2 thymoma viral proto-oncogene 2
15560 Htr2c 5-hydroxytryptamine (serotonin) receptor 2C
16334 Ins2 insulin II
16367 Irs1 insulin receptor substrate 1
16846 Lep leptin
16847 Lepr leptin receptor
18023 Nfe2l1 nuclear factor, erythroid derived 2,-like 1
18759 Prkci protein kinase C, iota
20526 Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2
20528 Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4
Displaying entry 21 - 21 of 21 in total
Gene ID Gene Symbol Description Source
362282 Pck1 phosphoenolpyruvate carboxykinase 1
Displaying all 2 entries
Gene ID Gene Symbol Description Source
33496 lilli lilliputian
42549 InR Insulin-like receptor
Displaying all 3 entries
Gene ID Gene Symbol Description Source
176000 ogt-1 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase;protein O-GlcNAc transferase
177850 gon-1 A disintegrin and metalloproteinase with thrombospondin motifs gon-1;Peptidase M12B domain-containing protein
266823 parp-1 Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
856386 LAG1 sphingosine N-acyltransferase LAG1
Related Glycoprotein
Displaying 1 entry
UniProt ID Protein Name Source
P38703 Ceramide synthase LAG1
The Human Phenotype Ontology
Displaying all 4 entries
HPO ID HPO Term
HP:0003584 Late onset
HP:0000006 Autosomal dominant inheritance
HP:0000855 Insulin resistance
HP:0005978 Type II diabetes mellitus
Displaying all 6 entries
Gene ID Gene Symbol Description
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
2820 GPD2 glycerol-3-phosphate dehydrogenase 2
6514 SLC2A2 solute carrier family 2 member 2
2645 GCK glucokinase
5506 PPP1R3A protein phosphatase 1 regulatory subunit 3A
3990 LIPC lipase C, hepatic type
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025