GlyCosmos Portal

Rattus norvegicus (Norway rat)

Summary

Taxonomy ID: 10116
PubChem Taxonomy: 10116

Genes (449) Glycans (773) Glycoproteins (2935) Lectins (166) Pathways (1070)

Displaying entries **226 - 250** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol
Breakdown of the nuclear lamina	Caspase-6 Lamin-B1 Prelamin-A/C	O35397 P48679 P70615	Casp6 Lmn1 Lmna Lmnb1 Mch2
Heme degradation	ATP-binding cassette sub-family C member 2 Albumin Biliverdin reductase A Broad substrate specificity ATP-binding cassette transporter ABCG2 Fatty acid-binding protein, liver Glutathione S-transferase A6 Glutathione S-transferase alpha-1 Glutathione S-transferase alpha-2 Glutathione S-transferase alpha-3 Glutathione S-transferase alpha-5 Heme oxygenase 1 Heme oxygenase 2 Multidrug resistance-associated protein 1 NAD(P)-binding domain-containing protein Solute carrier organic anion transporter family member 1B2 Solute carrier organic anion transporter family member 2B1 UDP-glucuronosyltransferase 1-2 UDP-glucuronosyltransferase 1A1 UDP-glucuronosyltransferase 1A3 UDP-glucuronosyltransferase 1A5	A0A8I6A3K7 P00502 P02692 P02770 P04903 P04904 P06762 P20720 P23711 P46418 P46844 Q63120 Q64550 Q64637 Q64638 Q6AXY0 Q80W57 Q8CG09 Q9JHI3 Q9QZX8	Abcc1 Abcc2 Abcg2 Alb Bcrp1 Blvr Blvra Cmoat Cmrp ENSRNOG00000064875 Fabp1 Gsta1 Gsta2 Gsta3 Gsta5 Gsta6 Gstyc1 Gstyc2 Hmox1 Hmox2 Mrp1 Mrp2 Oatp1b2 Oatp2b1 Slc21a10 Slc21a9 Slco1b2 Slco2b1 Ugt1 Ugt1a1 Ugt1a2 Ugt1a3 Ugt1a5
Pyrimidine catabolism	5', 3'-nucleotidase, cytosolic 5',3'-nucleotidase, mitochondrial 5'-nucleotidase, cytosolic IA 5'-nucleotidase 5'-nucleotidase Beta-ureidopropionase Dihydropyrimidinase Dihydropyrimidine dehydrogenase [NADP(+)] Thymidine phosphorylase Uridine phosphorylase Uridine phosphorylase	A0A8I5ZYY7 A0A8I6AHB0 D3ZWR1 D4A5J2 D4A9N9 F7F0D5 O89000 P21588 Q03248 Q5FVR2 Q63150	Bup1 DPD Dpyd Dpys Ecgf1 Nt5 Nt5c Nt5c1a Nt5c3a Nt5e Nt5m Nte Tymp Upb1 Upp1 Upp2
Beta oxidation of hexanoyl-CoA to butanoyl-CoA	Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Short-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P14604 P15651 Q60587 Q64428 Q9WVK7	Acads Echs1 Had Hadh Hadha Hadhb Hadhsc Schad
RNA Polymerase I Promoter Opening	Histone H2A type 2-A Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H3.1 Histone H3.3 Histone H3 Histone H4 Methyl-CpG binding domain protein 2 Mitogen-activated protein kinase 3 Nucleolar transcription factor 1	A0A0G2JXI9 A0A8I5ZSA8 A0A8I5ZYY0 A0A8I6A2W1 A0A8I6A7P3 A0A8I6AFW8 A0A8I6AWT3 A0A8I6G659 A9UMV8 D3ZJ08 D3ZVK7 D3ZXP3 D4A986 D4ACM0 G3V9C7 M0RBQ5 P0CC09 P21708 P25977 P62804 P84245 Q00729 Q6LED0	ENSRNOG00000062927 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 Erk1 H2ab3 H2ac10 H2ac18 H2ac4 H2afb3 H2afx H2aj H2ax H2az2 H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H3-3b H3.3b H3c13 H3f3b H4c16 H4c2 H4f16 H4ft Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist2h2aa3 Hist2h3c2 Hist4 Hist4h4 LOC100365043 LOC100910200 LOC120097726 LOC684797 Mapk3 Mbd2 Prkm3 Tcfubf Th2b Ubf-1 Ubtf
Ciprofloxacin ADME	Albumin Broad substrate specificity ATP-binding cassette transporter ABCG2 Solute carrier family 22 member 1 Solute carrier organic anion transporter family member 1A4	O35913 P02770 Q63089 Q80W57	Abcg2 Alb Bcrp1 Oatp1a4 Oatp2 Oct1 Slc21a5 Slc22a1 Slco1a4
Negative feedback regulation of MAPK pathway	Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 RAF proto-oncogene serine/threonine-protein kinase non-specific serine/threonine protein kinase	A0A8I6ATH0 P11345 P21708 P36506 P63086 Q01986	Braf Erk1 Erk2 Map2k1 Map2k2 Mapk Mapk1 Mapk3 Mek1 Mek2 Mkk2 Prkm1 Prkm3 Prkmk1 Prkmk2 Raf Raf1
FLT3 Signaling	Forkhead box O3 GRB2-associated-binding protein 2 GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 10 Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase SOS Ras/Rac guanine nucleotide exchange factor 1 receptor protein-tyrosine kinase	A0A0G2JW59 A0A0G2K344 D3ZBQ1 D4A3T0 P08644 P0CE43 P20171 P47196 P47197 P62994 Q04970 Q63484 Q63787 Q9EQH1	Akt1 Akt2 Akt3 Ash Flt3 Foxo3 Gab2 Grb10 Grb2 Hras Hras1 Kras Kras2 Nras Pik3ca Pik3r1 Sos1
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)	Dipeptidyl peptidase 4 Free fatty acid receptor 1 Gastric inhibitory polypeptide Glucose-dependent insulinotropic receptor	P14740 Q06145 Q7TQN8 Q8K3T4	Cd26 Dpp4 Ffar1 Gip Gpr119 Gpr40
RHOJ GTPase cycle	DEP domain containing 1B Dedicator of cytokinesis 8 Inositol polyphosphate 5-phosphatase OCRL Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Ras homolog family member J Rho GTPase activating protein 1 Rho GTPase activating protein 21 Rho GTPase activating protein 32 Rho GTPase activating protein 5 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 Rho GTPase-activating protein SYDE1 Triple functional domain protein	A0A0G2JYR5 A0A0G2K7N9 A0A8I6A829 A0A8I6APL5 A0A8I6GDA1 A0A8I6GLR6 D3ZGS3 D3ZZN9 D4AA32 F1M0Z1 F1MAK3 P0CAX5 P81128 Q5RJS2 Q63787 Q63788	Arhgap1 Arhgap21 Arhgap26 Arhgap32 Arhgap35 Arhgap5 Depdc1b Dock8 Grlf1 Ocrl Ophn1 P190A Pik3r1 Pik3r2 Prex1 Rhoj Syde1 Trio p190ARHOGAP
Activation of PKB	3-phosphoinositide-dependent protein kinase 1 Acyl-coenzyme A thioesterase THEM4 RAC-beta serine/threonine-protein kinase Tribbles homolog 3	O55173 P47197 Q566R0 Q9WTQ6	Akt2 Nipk Pdk1 Pdpk1 Them4 Trib3
Invadopodia formation	ADAM metallopeptidase domain 12 ADAM metallopeptidase domain 19 Disintegrin and metalloproteinase domain-containing protein 15 SH3 and PX domains 2A	A0A8I6AGQ6 A0A8I6G2U9 D3ZPM7 Q9QYV0	Adam12 Adam15 Adam19 Mdc15 Sh3pxd2a
Apoptotic cleavage of cellular proteins	Adenomatous polyposis coli protein Apoptotic chromatin condensation inducer 1 B-cell receptor-associated protein Baculoviral IAP repeat-containing 2 Caspase 7 Caspase-3 Caspase-6 Caspase-8 Claspin DNA-binding protein SATB Focal adhesion kinase 1 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Protein kinase C delta type Protein kinase C theta type Rho-associated protein kinase 1 Serine/threonine-protein kinase 24 Tyrosine-protein kinase non-specific serine/threonine protein kinase	A0A0G2JXK2 A0A0G2JYZ8 A0A8I5ZQU7 A0A8I6GBQ0 B0LT89 D3ZHC3 E9PST5 F1LVI0 O35346 O35397 P09215 P55213 P70478 Q04631 Q63644 Q6P6S1 Q9JHX4 Q9WTQ0	Acin1 Apc Bcap31 Birc2 Bmx Casp3 Casp6 Casp7 Casp8 Clspn Cpp32 Fak Fak1 Fnta Mch2 Mst3 Pkcd Pkcq Prkcd Prkcq Ptk2 Rock1 Satb1 Stk24 Stk26 Stk3
Common Pathway of Fibrin Clot Formation	Ac2-248 CD177 molecule Coagulation factor VIII Coagulation factor X Coagulation factor XIII A chain Coagulation factor XIII B chain Endothelial protein C receptor Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Glia-derived nexin Heparin cofactor 2 Platelet factor 4 Proteinase 3 Proteinase-activated receptor 1 Prothrombin Serpin family A member 5 Thrombomodulin Vitamin K-dependent protein C Vitamin K-dependent protein S	A0A8I6ARE6 B1H260 D3ZEB1 F7EMJ6 M0R8W9 O08619 O35370 P02680 P06399 P06765 P07092 P14480 P18292 P26824 P31394 P53813 Q4V8I1 Q63207 Q64268 Q7TPI9	Cd177 Cxcl4 F10 F13a F13a1 F13b F2 F2r F8 Fga Fgb Fgg Hcf2 Par1 Pf4 Pi7 Pn1 Proc Procr Pros Pros1 Prtn3 Scyb4 Serpina5 Serpinc1 Serpind1 Serpine2 Thbd
EML4 and NUDC in mitotic spindle formation	AT hook containing transcription factor 1 Aurora kinase B B9 domain-containing protein 2 BUB1 mitotic checkpoint serine/threonine kinase B BUB1 mitotic checkpoint serine/threonine kinase Baculoviral IAP repeat-containing protein 5 Borealin CAP-Gly domain-containing linker protein 1 CLIP-associating protein 2 Cell division cycle protein 20 homolog Centromere protein C Centromere protein E Centromere protein F Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein T Centromere protein U Centromere/kinetochore protein zw10 homolog Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Cytoplasmic linker associated protein 1 Cytoskeleton associated protein 5 DSN1 component of MIS12 kinetochore complex Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic EMAP like 4 ERCC excision repair 6 like, spindle assembly checkpoint helicase Exportin-1 Inner centromere protein Kinesin-like protein KIF2A Kinesin-like protein KIF2B Kinesin-like protein KIF2C Kinesin-like protein Kinetochore associated 1 Kinetochore protein NDC80 Kinetochore protein Nuf2 Kinetochore protein Spc24 Kinetochore protein Spc25 Kinetochore scaffold 1 LOC683983 protein Microtubule-associated protein RP/EB family member 1 Mitotic arrest deficient 1 like 1 Mitotic arrest deficient 2 like 1 NSL1 component of MIS12 kinetochore complex Nuclear distribution protein nudE homolog 1 Nuclear distribution protein nudE-like 1 Nuclear migration protein nudC Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup98-Nup96 Nucleoporin 133 Nucleoporin 160 Nucleoporin 37 Platelet-activating factor acetylhydrolase IB subunit alpha Polyamine-modulated factor 1 Protein MIS12 homolog Protein SEC13 homolog Protein Spindly Protein phosphatase 2 scaffold subunit A alpha Protein zwilch RAN GTPase activating protein 1 RAN binding protein 2 Regulator of chromosome condensation 2 Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase TAO1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Shugoshin 1 Shugoshin 2 Small ribosomal subunit protein eS27 Spindle and kinetochore-associated protein 1 Spindle and kinetochore-associated protein 2 Spindle and kinetochore-associated protein 2 ZW10 interactor	A0A0G2JW74 A0A0G2K160 A0A0G2K254 A0A0G2K2Z0 A0A0G2K3M4 A0A0G2K5R3 A0A1W2Q6F6 A0A8I5YC36 A0A8I5ZMG6 A0A8I5ZRC2 A0A8I5ZZ56 A0A8I6A3Y0 A0A8I6A596 A0A8I6A6K6 A0A8I6ADJ6 A0A8I6AEZ5 A0A8I6ALB1 A0A8I6G7C3 A0A8I6G9X6 B0BN28 B0BNB5 D3Z896 D3Z8B2 D3ZBL6 D3ZDI7 D3ZEH8 D3ZG58 D3ZV60 D3ZWI4 D4A0G9 D4A1C5 D4A5D3 D4A624 D4A9X9 D4AC25 D4ACM2 E9PSW8 E9PT83 F1LMI1 F1LVV4 F1M389 F1M3N2 O55099 O88664 P0C5J3 P38650 P49793 P52590 P62716 P63004 P63088 P63170 P63331 Q3KR99 Q3ZAU7 Q4QQS8 Q4QQT4 Q4V8C2 Q4V8G7 Q561R1 Q5I0J4 Q5M856 Q5U1Z7 Q5U2W4 Q5XFW8 Q5XI34 Q5XI51 Q62623 Q62673 Q62698 Q62871 Q62909 Q63100 Q63517 Q63525 Q66H02 Q66HR2 Q6AXW0 Q6AYL9 Q71TY3 Q78P75 Q78PB6 Q7TQ72 Q80U96 Q80W83 Q8VIL3 Q99JD4 Q9ES39 Q9JHY7 Q9JK25 Q9QXU8 Q9WV63	Ahctf1 Aik2 Aim1 Airk2 Ark2 Aurkb B9d2 Birc5 Bub1 Bub1b Ccdc99 Cdc20 Cdca1 Cdca8 Cenpc Cenpc1 Cenpe Cenpf Cenph Cenpi Cenpk Cenpl Cenpm Cenpn Cenpo Cenpp Cenpq Cenpr Cenpt Cenpu Ckap5 Clasp1 Clasp2 Clip1 Crm1 Cyln1 Dhc1 Dlc2 Dnch1 Dnchc1 Dnci1 Dnci2 Dncic1 Dncic2 Dncl1 Dnclc1 Dncli1 Dncli2 Dnec1 Dsn1 Dyhc Dync1h1 Dync1i1 Dync1i2 Dync1li1 Dync1li2 Dynll1 Dynll2 Eml4 Ercc6l Fam33a Fshprh1 Incenp Itgb3bp Kif18a Kif2 Kif2a Kif2b Kif2c Knl1 Kntc1 Krp2 LOC100909468 LOC102555739 LOC679342 LOC681185 LOC683983 Lis-1 Lis1 Lrpr1 Mad1l1 Mad2l1 Map1c Mapre1 Mis12 Mlf1ip Ndc80 Nde1 Ndel1 Nrif3 Nsl1 Nudc Nude Nude1 Nude2 Nudel Nuf2 Nup107 Nup133 Nup160 Nup37 Nup43 Nup85 Nup98 Pafah1b1 Pafaha Pcnt1 Pin Plk Plk1 Pmf1 Ppp1cc Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5a Ppp2r5b Ppp2r5c Ppp2r5d Ppp2r5e Ranbp2 Rangap1 Rcc2 Rps27 Rsn S27-1 Sec13 Sec13l1 Sgo1 Sgo2 Sip30 Ska1 Ska2 Ska2l1 Spbc25 Spc24 Spc24-ps1 Spc25 Spdl1 Stk1 Stk12 Stk5 Tao1 Taok1 Xpo1 Zw10 Zwilch Zwint
The NLRP3 inflammasome	Heat shock protein HSP 90-beta NACHT, LRR and PYD domains-containing protein 3 P2X purinoceptor 7 PYD and CARD domain containing Pannexin-1 Proline-serine-threonine phosphatase-interacting protein 1 Protein SGT1 homolog Pyrin Thioredoxin-interacting protein Thioredoxin	B0BN85 B0BNK4 D4A523 G3V8L1 P11232 P34058 P60570 Q5M7W1 Q64663 Q9JJ25	Hsp84 Hsp90ab1 Hspc3 Hspcb Mefv Nlrp3 P2rx7 Panx1 Pstpip1 Px1 Pycard Sugt1 Txn Txn1 Txnip Vdup1
L13a-mediated translational silencing of Ceruloplasmin expression	40S ribosomal protein S12 40S ribosomal protein S26 40S ribosomal protein S7 60S ribosomal protein L29 60S ribosomal protein L29 60S ribosomal protein L36 60S ribosomal protein L36a-like Eukaryotic initiation factor 4A-I Eukaryotic initiation factor 4A-II Eukaryotic translation initiation factor 1A Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3, X-linked Eukaryotic translation initiation factor 3 subunit A Eukaryotic translation initiation factor 3 subunit B Eukaryotic translation initiation factor 3 subunit C Eukaryotic translation initiation factor 3 subunit D Eukaryotic translation initiation factor 3 subunit E Eukaryotic translation initiation factor 3 subunit F Eukaryotic translation initiation factor 3 subunit G Eukaryotic translation initiation factor 3 subunit H Eukaryotic translation initiation factor 3 subunit I Eukaryotic translation initiation factor 3 subunit J Eukaryotic translation initiation factor 3 subunit K Eukaryotic translation initiation factor 3 subunit L Eukaryotic translation initiation factor 3 subunit M Eukaryotic translation initiation factor 4 gamma 1 Eukaryotic translation initiation factor 4E Eukaryotic translation initiation factor 4H Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL29 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL34 Large ribosomal subunit protein eL37 Large ribosomal subunit protein eL37 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 C-terminal domain-containing protein Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23 Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5 Large ribosomal subunit protein uL6 Large ribosomal subunit protein uL6 Polyadenylate-binding protein 1 Ribosomal protein L10-like Ribosomal protein L3-like Ribosomal protein L36A, pseudogene 5 Ribosomal protein L39-like Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27-like Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS4 Small ribosomal subunit protein eS4 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Ubiquitin B-like Ubiquitin-like protein FUBI Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JXD0 A0A8I5XWB0 A0A8I5ZLD0 A0A8I5ZWF3 A0A8I5ZX29 A0A8I6A1H0 A0A8I6A5Y3 A0A8I6AIB7 A0A8I6G4V0 A0A8I6G5P0 A0A8I6GEL5 A0JPM9 B0BNA7 B5DFC8 D3Z8D7 D3ZAZ0 D3ZF07 D3ZIV1 D3ZPN7 D3ZT78 D3ZTT9 D3ZX01 D3ZZ95 D4A4W9 D4A771 D4A8N3 D4A9G1 D4AC36 F1LT35 F7F7A6 F8WFR5 M0R665 M0R7E5 M0RD03 P02401 P04644 P05426 P05765 P09895 P12001 P12749 P13471 P17074 P17077 P17078 P17702 P18445 P19944 P19945 P21531 P21533 P23358 P24049 P24050 P24051 P25886 P27952 P29314 P35427 P38983 P41123 P47198 P49242 P50878 P60868 P61314 P61354 P61928 P62083 P62243 P62246 P62250 P62268 P62271 P62275 P62278 P62282 P62425 P62703 P62718 P62755 P62832 P62845 P62850 P62853 P62856 P62859 P62890 P62893 P62902 P62907 P62909 P62912 P62914 P62919 P62982 P63074 P63174 P63326 P68101 P81795 P83732 P83883 P84100 Q05474 Q1JU68 Q3ZB89 Q4G061 Q5RK09 Q5RKI1 Q5XI72 Q63507 Q641X8 Q6AYK8 Q6P9U8 Q6PDV7 Q6VV72 Q71TY3 Q9EPH8	AABR07029195.1 AABR07031505.1 AABR07060610.1 AABR07064810.1 AABR07071986.1 AABR07072260.1 Arbp EIF3EIP EIF3F EIF3K EIF3L EIF3M EIF3S12 EIF3S5 EIF3S6IP ENSRNOG00000068086 Eif1a Eif2a Eif2g Eif2s1 Eif2s2 Eif2s3 Eif2s3x Eif3a Eif3b Eif3c Eif3d Eif3e Eif3f Eif3g Eif3h Eif3i Eif3j Eif3k Eif3l Eif3m Eif3s1 Eif3s10 Eif3s2 Eif3s3 Eif3s4 Eif3s6 Eif3s7 Eif3s8 Eif3s9 Eif4a1 Eif4a2 Eif4e Eif4g1 Eif4h Fau Fte-1 Fte1 Int6 LOC100360645 LOC100361060 LOC100361854 LOC100361933 LOC100910714 LOC102550668 LOC103692829 LOC108351255 LOC120093247 LOC120094652 LOC120097744 LOC120099964 LOC120103572 Lamr1 Pabp1 Pabpc1 RGD1562402 RGD1563956 RGD1564606 Rig Rp2 Rpl1 Rpl10 Rpl10a Rpl10l Rpl10l1 Rpl11 Rpl12 Rpl12-ps2 Rpl12l2 Rpl13 Rpl13a Rpl14 Rpl15 Rpl17 Rpl18 Rpl18a Rpl19 Rpl21 Rpl21-ps26 Rpl21l2 Rpl21l3 Rpl21l5 Rpl22 Rpl23 Rpl23al1 Rpl24 Rpl26 Rpl27 Rpl27a Rpl27al3 Rpl28 Rpl29 Rpl3 Rpl30 Rpl31 Rpl32 Rpl34 Rpl34-ps1 Rpl34l1 Rpl34l2 Rpl35 Rpl35al8 Rpl36a Rpl36al-ps5 Rpl36al1 Rpl36l3 Rpl37 Rpl37l4 Rpl38 Rpl39 Rpl39l1 Rpl3l Rpl4 Rpl44 Rpl5 Rpl6 Rpl7 Rpl7a Rpl8 Rpl9 Rpl9l2 Rplp0 Rplp1 Rplp2 Rps10 Rps11 Rps12l8 Rps13 Rps14 Rps15 Rps15a Rps16 Rps17 Rps18 Rps19 Rps2 Rps20 Rps21 Rps23 Rps24 Rps25 Rps26 Rps26-ps13 Rps26l2 Rps26l4 Rps26l6 Rps27 Rps27a Rps27l Rps28 Rps29 Rps3 Rps3a Rps4 Rps4x Rps4y2 Rps5 Rps6 Rps7 Rps7-ps23 Rps8 Rps9 Rpsa S27-1 Uba80 Ubbl1 Ubcep1 Ubcl1 Wbscr1
MET activates RAS signaling	GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Mucin 20, cell surface associated RAN binding protein 10 Ran-binding protein 9 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	A0A8I5Y176 A0A8I6AAU0 D3Z7Z5 D4A3T0 P08644 P17945 P20171 P62994 P97523 Q04970 Q5M824	Ash Grb2 Hgf Hras Hras1 Kras Kras2 Met Muc20 Nras Ranbp10 Ranbp9 Shc1 Sos1
SIRT1 negatively regulates rRNA expression	Histone H2A type 2-A Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H3.1 Histone H3.3 Histone H3 Histone H4 Histone-lysine N-methyltransferase NAD-dependent protein deacetylase sirtuin-1 Ribosomal RNA-processing protein 8	A0A0G2JXI9 A0A0G2JZ79 A0A8I5ZSA8 A0A8I5ZYY0 A0A8I6A2W1 A0A8I6A3A4 A0A8I6A7P3 A0A8I6AFW8 A0A8I6AWT3 A0A8I6G659 A9UMV8 D3ZJ08 D3ZVK7 D3ZXP3 D4ACM0 G3V9C7 M0RBQ5 P0CC09 P62804 P84245 Q00729 Q5U4F0 Q6LED0	ENSRNOG00000062927 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 H2ab3 H2ac10 H2ac18 H2ac4 H2afb3 H2afx H2aj H2ax H2az2 H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H3-3b H3.3b H3c13 H3f3b H4c16 H4c2 H4f16 H4ft Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist2h2aa3 Hist2h3c2 Hist4 Hist4h4 LOC100365043 LOC100910200 LOC120097726 LOC684797 Rrp8 Sirt1 Suv39h1 Th2b
IRAK2 mediated activation of TAK1 complex	Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase kinase kinase 7 Polyubiquitin-B Polyubiquitin-C TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TNF receptor-associated factor 6 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0U1RRU5 A0A8I6A5Y3 A0A8I6ABN5 B5DF45 P0C8E4 P0CG51 P62982 Q4QQS0 Q5U303 Q63429	Irak2 LOC100360645 Map3k7 Map3k7ip2 Rps27a Tab1 Tab2 Tab3 Traf6 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1
Condensation of Prophase Chromosomes	Condensin-2 complex subunit D3 Condensin-2 complex subunit H2 Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 Histone H2A type 2-A Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H4 Microcephalin Non-SMC condensin II complex, subunit G2 PHD finger protein 8 Protein SET Retinoblastoma-associated protein Serine/threonine-protein kinase PLK1 Structural maintenance of chromosomes protein Structural maintenance of chromosomes protein [histone H4]-lysine(20) N-methyltransferase	A0A0G2JXI9 A0A140UHX3 A0A8I5ZSA8 A0A8I5ZYY0 A0A8I6A2W1 A0A8I6A7P3 A0A8I6AFW8 A0A8I6AWT3 A0A8I6G659 A0A8I6GK63 A0A8I6GKG3 A9UMV8 D3ZJM7 D3ZVK7 D3ZXP3 D4A5Q2 D4AAL2 D4ACM0 D4AD31 G3V9C7 M0RBQ5 P0CC09 P30277 P33568 P39951 P62804 Q00729 Q4V8I2 Q62673 Q63945	Ccnb1 Cdc2 Cdc2a Cdk1 Cdkn1 ENSRNOG00000062927 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 H2ab3 H2ac10 H2ac18 H2ac4 H2afb3 H2afx H2aj H2ax H2az2 H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H4c16 H4c2 H4f16 H4ft Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist2h2aa3 Hist4 Hist4h4 Kmt5a LOC100365043 LOC100910200 LOC120097726 LOC684797 Mcph1 Ncapd3 Ncapg2 Ncaph2 Phf8 Plk Plk1 Rb-1 Rb1 Set Smc2 Smc4 Th2b
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	Erythropoietin receptor Erythropoietin GRB2-associated binding protein 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphoinositide 3-kinase regulatory subunit 5 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0G2K344 A0A8I5Y949 D3ZAL7 D3ZFJ0 D4A4I3 F1MAL5 P29676 Q07014 Q07303 Q62689 Q63787 Q9Z1L0	Epo Epor Gab1 Irs2 Jak2 Lyn Pik3ca Pik3cb Pik3cd Pik3cg Pik3r1 Pik3r5
G alpha (12/13) signalling events	A-kinase anchor protein 13 Active breakpoint cluster region-related protein Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Ephexin-1 Epithelial cell transforming 2 FYVE, RhoGEF and PH domain containing 1 FYVE, RhoGEF and PH domain containing 2 FYVE, RhoGEF and PH domain containing 3 FYVE, RhoGEF and PH domain-containing protein 4 Guanine nucleotide exchange factor DBS Guanine nucleotide-binding protein subunit alpha-12 Guanine nucleotide-binding protein subunit alpha-13 Intersectin-1 Kalirin LOC687105 protein MCF.2 cell line derived transforming sequence Neuroepithelial cell transforming 1 Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Pleckstrin homology and RhoGEF domain containing G2 Pleckstrin homology domain-containing family G member 5 Plexin B1 Proto-oncogene vav Ras-specific guanine nucleotide-releasing factor 2 Rho guanine nucleotide exchange factor 10 like Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 33 Rho guanine nucleotide exchange factor 37 Rho guanine nucleotide exchange factor 38 Rho guanine nucleotide exchange factor 39 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 6 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related GTP-binding protein RhoB SOS Ras/Rac guanine nucleotide exchange factor 1 SOS Ras/Rho guanine nucleotide exchange factor 2 TIAM Rac1 associated GEF 1 TIAM Rac1 associated GEF 2 Thromboxane A2 receptor Transforming protein RhoA Triple functional domain protein Tyrosine-protein kinase Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 non-specific serine/threonine protein kinase	A0A0G2JTR4 A0A0G2JTU0 A0A0G2JUP3 A0A0G2JXT9 A0A0G2K6M9 A0A0G2K860 A0A8I5ZMG2 A0A8I5ZPB5 A0A8I5ZZX2 A0A8I6A9Q4 A0A8I6AC12 A0A8I6AL39 A0A8I6AVA8 A0A8I6G7U0 A0A8I6GLR6 A1IGU3 B0BN40 B2GUW2 D3Z9I3 D3ZDX5 D3ZMS5 D3ZUD0 D3ZYG0 D4A1D2 D4A3T0 D4A646 D4AD85 E9PT59 F1M0Z1 F1M3G7 F1MAI3 G3V9A0 M0R3X3 M0RBM9 O55043 O88387 P15823 P23944 P34978 P43140 P54100 P61589 P62747 P97924 Q5BKC9 Q5FVC2 Q5XXR3 Q62868 Q63210 Q63406 Q63644 Q6P720 Q6Q7Y5 Q6RFZ7 Q99JE4 Q9ES67 Q9QX73 Q9WVE9 Q9Z1I6	Abr Adra1a Adra1b Adra1c Adra1d Akap13 Arha Arha2 Arhb Arhgef1 Arhgef10 Arhgef10l Arhgef11 Arhgef12 Arhgef15 Arhgef16 Arhgef17 Arhgef19 Arhgef2 Arhgef25 Arhgef26 Arhgef3 Arhgef33 Arhgef37 Arhgef38 Arhgef39 Arhgef5 Arhgef6 Arhgef7 Arhgef9 Btk Duo Ect2 Ehsh1 Fgd1 Fgd2 Fgd3 Fgd4 Geft Gna12 Gna13 Grf2 Hapip Itsn Itsn1 Kalrn LOC687105 Lsc Mcf2 Mcf2l Net1 Ngef Obscn Ost Pak3bp Pixb Plekhg2 Plekhg5 Plxnb1 Prex1 RGD1565043 Rasgrf2 Rhoa Rhob Rock1 Rock2 Rt13 Sos1 Sos2 Tbxa2r Tech Tiam1 Tiam2 Trio Vav Vav1 Vav2 Vav3
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	BCL2 interacting protein 3 like Metalloreductase STEAP3 Serine-protein kinase ATM Zinc finger protein 420	A0A8I6AG85 D3Z901 D4ACL8 Q5RKL5	Atm Bnip3l Steap3 Zfp420
Signaling by Activin	Activin receptor type-1B Activin receptor type-1C Activin receptor type-2A Activin receptor type-2B Inhibin alpha chain Inhibin beta A chain Inhibin beta B chain Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Transforming growth factor beta receptor type 3	O70436 O70437 P17490 P17491 P18331 P21708 P26342 P38444 P38445 P63086 P70539 P80202 P84025	Actrii Actriib Acvr1b Acvr1c Acvr2 Acvr2a Acvr2b Acvrlk4 Alk4 Alk7 Erk1 Erk2 Inha Inhba Inhbb Madh2 Madh3 Madh4 Mapk Mapk1 Mapk3 Prkm1 Prkm3 Smad2 Smad3 Smad4 Tgfbr3

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