Homo sapiens (human)

Summary
Taxonomy ID
9606
PubChem Taxonomy
9606
Displaying entries 1651 - 1675 of 2090 in total
Pathway Name Protein Name UniProt ID Gene Symbol ▲ GlyTouCan ID
Defective SLC11A2 causes hypochromic microcytic anemia, with iron overload 1 (AHMIO1)
  • DCT1
  • DMT1
  • NRAMP2
  • SLC11A2
Essential pentosuria
  • DCXR
  • SDR20C1
Z-decay: degradation of maternal mRNAs by zygotically expressed factors
  • DDX2A
  • DDX2B
  • DDX48
  • DIS3L2
  • EIF4A
  • EIF4A1
  • EIF4A2
  • EIF4A3
  • EIF4B
  • EIF4E
  • EIF4EL1
  • EIF4F
  • EIF4G
  • EIF4G1
  • EIF4GI
  • FAM6A
  • HS2
  • KIAA0111
  • KIAA0191
  • KIAA1711
  • PAB1
  • PAB2
  • PABP
  • PABP1
  • PABP2
  • PABPC1
  • PABPC2
  • PABPN1
  • PAIP1
  • TUT4
  • TUT7
  • ZCCHC11
  • ZCCHC6
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
  • DDX2A
  • DDX2B
  • EIF4A
  • EIF4A1
  • EIF4A2
  • EIF4B
  • EIF4E
  • EIF4EBP1
  • EIF4EL1
  • EIF4F
  • EIF4G
  • EIF4G1
  • EIF4GI
  • EIF4H
  • KIAA0038
  • WBSCR1
  • WSCR1
DEx/H-box helicases activate type I IFN and inflammatory cytokines production
  • DDX36
  • DDX9
  • DHX36
  • DHX9
  • IRF7
  • KIAA1488
  • LKP
  • LYT10
  • MLEL1
  • MYD88
  • NDH2
  • NFKB1
  • NFKB2
  • NFKB3
  • RELA
  • RHAU
Replication of the SARS-CoV-2 genome
  • DDX5
  • G17P1
  • HELR
  • HLR1
  • RB1
  • VHL
  • ZCRB1
  • rep
HHAT G278V doesn't palmitoylate Hh-Np
  • DHH
  • HHAT
  • IHH
  • MART2
  • SHH
  • SKI1
Hypusinylation
  • DHPS
  • DOHH
  • DS
  • EIF5A
  • EIF5A2
  • HLRC1
Sulfide oxidation to sulfate
  • DIC
  • ETHE1
  • HSCO
  • KAT
  • SLC25A10
  • SQOR
  • SQRDL
  • SUOX
  • TST
  • TSTD1
Translesion synthesis by POLK
  • DINB1
  • MAD2B
  • MAD2L2
  • PCNA
  • POLK
  • POLZ
  • REPA1
  • REPA2
  • REPA3
  • REV1
  • REV1L
  • REV3
  • REV3L
  • REV7
  • RFC1
  • RFC140
  • RFC2
  • RFC3
  • RFC4
  • RFC5
  • RPA1
  • RPA14
  • RPA2
  • RPA3
  • RPA32
  • RPA34
  • RPA70
  • RPS27A
  • UBA52
  • UBA80
  • UBB
  • UBC
  • UBCEP1
  • UBCEP2
Negative regulation of TCF-dependent signaling by WNT ligand antagonists
  • DKK1
  • DKK2
  • DKK4
  • FRP
  • FRP1
  • FRP2
  • KREMEN
  • KREMEN1
  • KREMEN2
  • KRM1
  • KRM2
  • LR3
  • LRP5
  • LRP6
  • LRP7
  • SARP1
  • SARP2
  • SFRP1
  • SFRP2
  • SOST
  • WIF1
  • WNT14
  • WNT3A
  • WNT4
  • WNT5A
  • WNT9A
Signaling by LRP5 mutants
  • DKK1
  • DKK2
  • DKK4
  • KREMEN
  • KREMEN1
  • KREMEN2
  • KRM1
  • KRM2
  • LR3
  • LRP5
  • LRP7
Regulation of pyruvate dehydrogenase (PDH) complex
  • DLAT
  • DLD
  • DLTA
  • GCSL
  • GSTZ1
  • KIAA1348
  • KIAA1990
  • LAD
  • MAAI
  • PDHA1
  • PDHA2
  • PDHAL
  • PDHB
  • PDHK1
  • PDHK2
  • PDHK3
  • PDHK4
  • PDHX
  • PDK1
  • PDK2
  • PDK3
  • PDK4
  • PDP
  • PDP1
  • PDP2
  • PDPR
  • PDX1
  • PHE1A
  • PHE1B
  • PHE3
  • PPM2C
  • SIR2L4
  • SIRT4
PDH complex synthesizes acetyl-CoA from PYR
  • DLAT
  • DLD
  • DLTA
  • GCSL
  • LAD
  • PDHA1
  • PDHA2
  • PDHAL
  • PDHB
  • PDHX
  • PDX1
  • PHE1A
  • PHE1B
  • PHE3
Succinyl-CoA Biosynthesis
  • DLD
  • DLST
  • DLTS
  • GCSL
  • KGD4
  • LAD
  • MRPS36
  • OGDH
  • PHE3
Removal of the Flap Intermediate
  • DNA2
  • DNA2L
  • FEN1
  • KIAA0039
  • KIAA0083
  • PCNA
  • POLA
  • POLA1
  • POLA2
  • POLD
  • POLD1
  • POLD2
  • POLD3
  • POLD4
  • POLDS
  • PRIM1
  • PRIM2
  • PRIM2A
  • RAD2
  • REPA1
  • REPA2
  • REPA3
  • RPA1
  • RPA14
  • RPA2
  • RPA3
  • RPA32
  • RPA34
  • RPA70
Vitamin B1 (thiamin) metabolism
  • DNC
  • MUP1
  • SLC19A2
  • SLC19A3
  • SLC25A19
  • THT1
  • THTPA
  • TPK1
  • TRMA
Nef and signal transduction
  • DOCK2
  • ELMO1
  • FYN
  • HCK
  • KIAA0209
  • KIAA0281
  • LCK
  • PAK2
  • RAC1
  • TC25
  • nef
Activation of NOXA and translocation to mitochondria
  • DP1
  • DP2
  • E2F1
  • NOXA
  • P53
  • PMAIP1
  • RBBP3
  • TFDP1
  • TFDP2
  • TP53
Inhibition of replication initiation of damaged DNA by RB1/E2F1
  • DP1
  • DP2
  • E2F1
  • POLA
  • POLA1
  • POLA2
  • PPP2CA
  • PPP2CB
  • PPP2R1A
  • PPP2R1B
  • PPP2R3B
  • PPP2R3L
  • PRIM1
  • PRIM2
  • PRIM2A
  • RB1
  • RBBP3
  • TFDP1
  • TFDP2
Defective DPAGT1 causes CDG-1j, CMSTA2
  • DPAGT1
  • DPAGT2
SMAD4 MH2 Domain Mutants in Cancer
  • DPC4
  • MADH2
  • MADH3
  • MADH4
  • MADR2
  • SMAD2
  • SMAD3
  • SMAD4
SMAD2/3 MH2 Domain Mutants in Cancer
  • DPC4
  • MADH2
  • MADH3
  • MADH4
  • MADR2
  • SMAD2
  • SMAD3
  • SMAD4
Defective DPM1 causes CDG-1e
  • DPM1
  • DPM2
  • DPM3
Defective DPM2 causes CDG-1u
  • DPM1
  • DPM2
  • DPM3

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024