GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **976 - 1000** of **2074** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism
Signalling to p38 via RIT and RIN	Beta-nerve growth factor GTP-binding protein Rit1 GTP-binding protein Rit2 High affinity nerve growth factor receptor Serine/threonine-protein kinase B-raf	P01138 P04629 P15056 Q92963 Q99578	BRAF BRAF1 MTC NGF NGFB NTRK1 RAFB1 RIBB RIN RIT RIT1 RIT2 ROC1 ROC2 TRK TRKA	Homo sapiens (human)
Signalling to RAS	Beta-nerve growth factor GTPase HRas GTPase NRas High affinity nerve growth factor receptor SHC-transforming protein 1 SHC-transforming protein 2 SHC-transforming protein 3 Son of sevenless homolog 1	P01111 P01112 P01138 P04629 P29353 P98077 Q07889 Q92529	HRAS HRAS1 MTC NGF NGFB NRAS NSHC NTRK1 SCK SHC SHC1 SHC2 SHC3 SHCA SHCB SHCC SOS1 TRK TRKA	Homo sapiens (human)
PI3K/AKT activation	Beta-nerve growth factor High affinity nerve growth factor receptor Insulin receptor substrate 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Transforming protein RhoA	O00459 P01138 P04629 P27986 P35568 P42336 P42338 P61586 Q9Y4H2	ARH12 ARHA GRB1 IRS1 IRS2 MTC NGF NGFB NTRK1 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 RHO12 RHOA TRK TRKA	Homo sapiens (human)
Signalling to STAT3	Beta-nerve growth factor High affinity nerve growth factor receptor Signal transducer and activator of transcription 3	P01138 P04629 P40763	APRF MTC NGF NGFB NTRK1 STAT3 TRK TRKA	Homo sapiens (human)
TRKA activation by NGF	Beta-nerve growth factor High affinity nerve growth factor receptor	P01138 P04629	MTC NGF NGFB NTRK1 TRK TRKA	Homo sapiens (human)
p75NTR negatively regulates cell cycle via SC1	Beta-nerve growth factor Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 PR domain zinc finger protein 4 Tumor necrosis factor receptor superfamily member 16	O15379 P01138 P08138 Q13547 Q92769 Q9UKN5	HDAC1 HDAC2 HDAC3 NGF NGFB NGFR PFM1 PRDM4 RPD3L1 TNFRSF16	Homo sapiens (human)
p75NTR recruits signalling complexes	Beta-nerve growth factor Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 Myeloid differentiation primary response protein MyD88 Polyubiquitin-B Polyubiquitin-C Protein kinase C iota type Receptor-interacting serine/threonine-protein kinase 2 Sequestosome-1 TNF receptor-associated factor 6 Tumor necrosis factor receptor superfamily member 16 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14920 O43353 P01138 P08138 P0CG47 P0CG48 P41743 P51617 P62979 P62987 Q13501 Q99836 Q9Y4K3	CARDIAK DXS1179E IKBKB IKKB IRAK IRAK1 MYD88 NGF NGFB NGFR ORCA OSIL PRKCI RICK RIP2 RIPK2 RNF85 RPS27A SQSTM1 TNFRSF16 TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
NF-kB is activated and signals survival	Beta-nerve growth factor Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Sequestosome-1 TNF receptor-associated factor 6 Transcription factor p65 Tumor necrosis factor receptor superfamily member 16 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14920 P01138 P08138 P0CG47 P0CG48 P19838 P25963 P51617 P62979 P62987 Q04206 Q13501 Q9Y4K3	IKBA IKBKB IKKB IRAK IRAK1 MAD3 NFKB1 NFKB3 NFKBI NFKBIA NGF NGFB NGFR ORCA OSIL RELA RNF85 RPS27A SQSTM1 TNFRSF16 TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Axonal growth stimulation	Beta-nerve growth factor Rho GDP-dissociation inhibitor 1 Transforming protein RhoA Tumor necrosis factor receptor superfamily member 16	P01138 P08138 P52565 P61586	ARH12 ARHA ARHGDIA GDIA1 NGF NGFB NGFR RHO12 RHOA TNFRSF16	Homo sapiens (human)
NFG and proNGF binds to p75NTR	Beta-nerve growth factor Sortilin-related VPS10 domain containing receptor 3 Tumor necrosis factor receptor superfamily member 16	P01138 P08138 Q17R88	NGF NGFB NGFR SORCS3 TNFRSF16	Homo sapiens (human)
Ceramide signalling	Beta-nerve growth factor Sphingomyelin phosphodiesterase 2 Tumor necrosis factor receptor superfamily member 16	O60906 P01138 P08138	NGF NGFB NGFR SMPD2 TNFRSF16	Homo sapiens (human)
MTF1 activates gene expression	Beta-synuclein Cysteine and glycine-rich protein 1 Metal regulatory transcription factor 1	P21291 Q14872 Q16143	CSRP CSRP1 CYRP MTF1 SNCB	Homo sapiens (human)
Coenzyme A biosynthesis	Bifunctional coenzyme A synthase Dephospho-CoA kinase domain-containing protein Pantothenate kinase 1 Pantothenate kinase 2, mitochondrial Pantothenate kinase 3 Phosphopantothenate--cysteine ligase Phosphopantothenoylcysteine decarboxylase	Q13057 Q8TE04 Q8WVC6 Q96CD2 Q9BZ23 Q9H999 Q9HAB8	C20orf48 COAB COAC COASY DCAKD PANK PANK1 PANK2 PANK3 PPCDC PPCS	Homo sapiens (human)
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)	Bifunctional epoxide hydrolase 2 Cytochrome P450 1A1 Cytochrome P450 1A2 Cytochrome P450 1B1 Cytochrome P450 2C19 Cytochrome P450 2C8 Cytochrome P450 2C9 Cytochrome P450 2J2	P04798 P05177 P10632 P11712 P33261 P34913 P51589 Q16678	CYP1A1 CYP1A2 CYP1B1 CYP2C10 CYP2C19 CYP2C8 CYP2C9 CYP2J2 EPHX2	Homo sapiens (human)
Biosynthesis of maresins	Bifunctional epoxide hydrolase 2 Polyunsaturated fatty acid 5-lipoxygenase	P09917 P34913	ALOX5 EPHX2 LOG5	Homo sapiens (human)
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway	Bifunctional polynucleotide phosphatase/kinase DNA ligase 3 DNA polymerase beta DNA repair protein XRCC1 Endonuclease 8-like 1 Endonuclease 8-like 2 N-glycosylase/DNA lyase	O15527 P06746 P18887 P49916 Q969S2 Q96FI4 Q96T60	LIG3 MMH MUTM NEIL1 NEIL2 OGG1 OGH1 PNKP POLB XRCC1	Homo sapiens (human)
Chondroitin sulfate biosynthesis	Biglycan Brevican core protein Carbohydrate sulfotransferase 11 Carbohydrate sulfotransferase 12 Carbohydrate sulfotransferase 13 Carbohydrate sulfotransferase 15 Carbohydrate sulfotransferase 3 Carbohydrate sulfotransferase 7 Chondroitin sulfate N-acetylgalactosaminyltransferase 1 Chondroitin sulfate N-acetylgalactosaminyltransferase 2 Chondroitin sulfate glucuronyltransferase Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Chondroitin sulfate synthase 1 Chondroitin sulfate synthase 2 Chondroitin sulfate synthase 3 Decorin Neurocan core protein Versican core protein	O14594 O95196 P07585 P13611 P21810 Q6UVK1 Q70JA7 Q7LFX5 Q7LGC8 Q86X52 Q8IZ52 Q8N6G5 Q8NET6 Q8TDX6 Q96GW7 Q9NPF2 Q9NRB3 Q9NS84 Q9P2E5	BCAN BEHAB BGN BRAG CALEB CHGN CHGN2 CHPF CHPF2 CHST11 CHST12 CHST13 CHST15 CHST3 CHST7 CHSY CHSY1 CHSY2 CHSY3 CSGALNACT1 CSGALNACT2 CSGLCAT CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 CSS1 CSS2 CSS3 DCN GALNAC4S6ST GALNACT1 GALNACT2 KIAA0598 KIAA0990 KIAA1402 MCSP NCAN NEUR NGC SLRR1A SLRR1B VCAN	Homo sapiens (human)
Dermatan sulfate biosynthesis	Biglycan Brevican core protein Carbohydrate sulfotransferase 14 Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Dermatan-sulfate epimerase-like protein Dermatan-sulfate epimerase Neurocan core protein Uronyl 2-sulfotransferase Versican core protein	O14594 O95196 P07585 P13611 P21810 Q6UVK1 Q8IZU8 Q8NCH0 Q96GW7 Q9UL01 Q9Y2C2	BCAN BEHAB BGN C18orf4 CALEB CHST14 CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 D4ST1 DCN DS2ST DSE DSEL MCSP NCAG1 NCAN NEUR NGC SART2 SLRR1A SLRR1B UST VCAN	Homo sapiens (human)
Defective CHST14 causes EDS, musculocontractural type	Biglycan Brevican core protein Carbohydrate sulfotransferase 14 Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Neurocan core protein Versican core protein	O14594 O95196 P07585 P13611 P21810 Q6UVK1 Q8NCH0 Q96GW7	BCAN BEHAB BGN CALEB CHST14 CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 D4ST1 DCN MCSP NCAN NEUR NGC SLRR1A SLRR1B VCAN	Homo sapiens (human)
Defective CHST3 causes SEDCJD	Biglycan Brevican core protein Carbohydrate sulfotransferase 3 Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Neurocan core protein Versican core protein	O14594 O95196 P07585 P13611 P21810 Q6UVK1 Q7LGC8 Q96GW7	BCAN BEHAB BGN CALEB CHST3 CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 DCN MCSP NCAN NEUR NGC SLRR1A SLRR1B VCAN	Homo sapiens (human)
Defective CHSY1 causes TPBS	Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Chondroitin sulfate synthase 1 Decorin Neurocan core protein Versican core protein	O14594 O95196 P07585 P13611 P21810 Q6UVK1 Q86X52 Q96GW7	BCAN BEHAB BGN CALEB CHSY CHSY1 CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 CSS1 DCN KIAA0990 MCSP NCAN NEUR NGC SLRR1A SLRR1B VCAN	Homo sapiens (human)
Synthesis of bile acids and bile salts	Bile acid receptor Cholesterol 25-hydroxylase Cytochrome P450 7A1 Cytochrome P450 7B1 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Oxysterol-binding protein 1 Oxysterol-binding protein-related protein 1 Oxysterol-binding protein-related protein 2 Oxysterol-binding protein-related protein 3 Oxysterol-binding protein-related protein 6 Oxysterol-binding protein-related protein 7 Oxysterol-binding protein-related protein 9 Retinoic acid receptor RXR-alpha	O75881 O95992 P19793 P22059 P22680 Q15596 Q15788 Q96RI1 Q96SU4 Q9BXW6 Q9BZF2 Q9BZF3 Q9H1P3 Q9H4L5	BAR BHLHE74 BHLHE75 CH25H CYP7 CYP7A1 CYP7B1 FXR HRR1 KIAA0704 KIAA0772 NCOA1 NCOA2 NR1H4 NR2B1 ORP1 ORP2 ORP3 ORP6 ORP7 ORP9 OSBP OSBP1 OSBP3 OSBP4 OSBP8 OSBPL1 OSBPL1A OSBPL1B OSBPL2 OSBPL3 OSBPL6 OSBPL7 OSBPL9 RIP14 RXRA SRC1 SRC2 TIF2	Homo sapiens (human)
Defective ABCB11 causes PFIC2 and BRIC2	Bile salt export pump	O95342	ABCB11 BSEP	Homo sapiens (human)
Digestion of dietary lipid	Bile salt-activated lipase Colipase Gastric triacylglycerol lipase Inactive pancreatic lipase-related protein 1 Pancreatic lipase-related protein 2 Pancreatic lipase-related protein 3 Pancreatic triacylglycerol lipase	P04118 P07098 P16233 P19835 P54315 P54317 Q17RR3	BAL CEL CLPS LIPF PLRP1 PLRP2 PNLIP PNLIPRP1 PNLIPRP2 PNLIPRP3	Homo sapiens (human)
Defective BTD causes biotidinase deficiency	Biotinidase	P43251	BTD	Homo sapiens (human)

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