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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
osteoporosis
Summary
- Definition
- A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.
- Super Class
- bone resorption disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 1588 | CYP19A1 | cytochrome P450 family 19 subfamily A member 1 | |
| 1636 | ACE | angiotensin I converting enzyme | |
| 1834 | DSPP | dentin sialophosphoprotein | |
| 2099 | ESR1 | estrogen receptor 1 | |
| 2689 | GH2 | growth hormone 2 | |
| 2690 | GHR | growth hormone receptor | |
| 3459 | IFNGR1 | interferon gamma receptor 1 | |
| 3480 | IGF1R | insulin like growth factor 1 receptor | |
| 3481 | IGF2 | insulin like growth factor 2 | |
| 3486 | IGFBP3 | insulin like growth factor binding protein 3 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 16846 | Lep | leptin | |
| 16847 | Lepr | leptin receptor | |
| 16973 | Lrp5 | low density lipoprotein receptor-related protein 5 | |
| 17395 | Mmp9 | matrix metallopeptidase 9 | |
| 17869 | Myc | myelocytomatosis oncogene | |
| 18383 | Tnfrsf11b | tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) | |
| 18538 | Pcna | proliferating cell nuclear antigen | |
| 19219 | Ptger4 | prostaglandin E receptor 4 (subtype EP4) | |
| 20656 | Sod2 | superoxide dismutase 2, mitochondrial | |
| 21803 | Tgfb1 | transforming growth factor, beta 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 25235 | Ghr | growth hormone receptor | |
| 25341 | Tnfrsf11b | TNF receptor superfamily member 11B | |
| 25467 | Irs1 | insulin receptor substrate 1 | |
| 25608 | Lep | leptin | |
| 25718 | Igf1r | insulin-like growth factor 1 receptor | |
| 25737 | Pcna | proliferating cell nuclear antigen | |
| 29373 | Bmp2 | bone morphogenetic protein 2 | |
| 29393 | Col1a1 | collagen type I alpha 1 chain | |
| 59086 | Tgfb1 | transforming growth factor, beta 1 | |
| 60582 | Il1rn | interleukin 1 receptor antagonist |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 380373 | cxcr4.S | C-X-C motif chemokine receptor 4 S homeolog | Xenopus laevis (African clawed frog) | |
| 397873 | bmp2.L | bone morphogenetic protein 2 L homeolog | Xenopus laevis (African clawed frog) | |
| 398022 | igf1r.S | insulin like growth factor 1 receptor S homeolog | Xenopus laevis (African clawed frog) | |
| 100038176 | cxcr4 | C-X-C motif chemokine receptor 4 | Xenopus tropicalis (tropical clawed frog) | |
| 100144634 | ace | angiotensin I converting enzyme | Xenopus tropicalis (tropical clawed frog) | |
| 100192360 | cxcr4.L | C-X-C motif chemokine receptor 4 L homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 175410 | daf-2 | Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase | |
| 175942 | pdfr-1 | Calcitonin receptor-like protein 1 | |
| 179068 | dbl-1 | Protein dbl-1 | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180351 | W01F3.2 | Uncharacterized protein | |
| 180780 | acn-1 | Inactive angiotensin-converting enzyme-related protein |
