Sjogren's syndrome

Summary
Synonym
  • Sicca syndrome
  • Sjogren syndrome
  • xerodermosteosis
Definition
An autoimmune disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva.
Super Class
autoimmune disease of exocrine system
Disease Ontology
DOID:12894
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
Related Genes
Displaying entries 31 - 40 of 46 in total
Gene ID Gene Symbol Description Source
4747 NEFL neurofilament light chain
5444 PON1 paraoxonase 1
5967 REG1A regenerating family member 1 alpha
6304 SATB1 SATB homeobox 1
6403 SELP selectin P
6768 ST14 ST14 transmembrane serine protease matriptase
6775 STAT4 signal transducer and activator of transcription 4
7040 TGFB1 transforming growth factor beta 1
7057 THBS1 thrombospondin 1
7124 TNF tumor necrosis factor
Displaying entries 31 - 37 of 37 in total
Gene ID Gene Symbol Description Source
21947 Cd40lg CD40 ligand
22352 Vim vimentin
24099 Tnfsf13b tumor necrosis factor (ligand) superfamily, member 13b
59013 Hnrnph1 heterogeneous nuclear ribonucleoprotein H1
69550 Bst2 bone marrow stromal cell antigen 2
209590 Il23r interleukin 23 receptor
239611 Muc19 mucin 19
Displaying entries 11 - 20 of 25 in total
Gene ID Gene Symbol Description Source
25704 Il2ra interleukin 2 receptor subunit alpha
25712 Ifng interferon gamma
59086 Tgfb1 transforming growth factor, beta 1
60582 Il1rn interleukin 1 receptor antagonist
81687 Mmp9 matrix metallopeptidase 9
81818 Vim vimentin
83613 Nefl neurofilament light chain
84024 Pon1 paraoxonase 1
84349 Cd40lg CD40 ligand
116553 Il13 interleukin 13
Displaying 1 entry
Gene ID Gene Symbol Description Source
447803 pon1 paraoxonase 1
Displaying all 2 entries
Gene ID Gene Symbol Description Source Organism
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
Displaying all 6 entries
Gene ID Gene Symbol Description Source
171999 poml-2 Arylesterase
178748 zmp-3 Matrix metalloproteinase-C
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
187297 poml-1 PON (paraoxonase) and MEC-6 Like
188252 lev-9 Protein lev-9

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Acknowledgements

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Last updated: December 9, 2024