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Sjogren's syndrome
Summary
- Synonym
-
- Sicca syndrome
- Sjogren syndrome
- xerodermosteosis
- Definition
- An autoimmune disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva.
- Super Class
- autoimmune disease of exocrine system
External Links
- Disease Ontology
- DOID:12894
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- GARD
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 4747 | NEFL | neurofilament light chain | |
| 5444 | PON1 | paraoxonase 1 | |
| 5967 | REG1A | regenerating family member 1 alpha | |
| 6304 | SATB1 | SATB homeobox 1 | |
| 6403 | SELP | selectin P | |
| 6768 | ST14 | ST14 transmembrane serine protease matriptase | |
| 6775 | STAT4 | signal transducer and activator of transcription 4 | |
| 7040 | TGFB1 | transforming growth factor beta 1 | |
| 7057 | THBS1 | thrombospondin 1 | |
| 7124 | TNF | tumor necrosis factor |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 12064 | Bdnf | brain derived neurotrophic factor | |
| 12380 | Cast | calpastatin | |
| 12477 | Ctla4 | cytotoxic T-lymphocyte-associated protein 4 | |
| 12774 | Ccr5 | C-C motif chemokine receptor 5 | |
| 12775 | Ccr7 | C-C motif chemokine receptor 7 | |
| 13076 | Cyp1a1 | cytochrome P450, family 1, subfamily a, polypeptide 1 | |
| 14102 | Fas | Fas cell surface death receptor | |
| 14573 | Gdnf | glial cell line derived neurotrophic factor | |
| 14960 | H2-Aa | histocompatibility 2, class II antigen A, alpha | |
| 14961 | H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 171999 | poml-2 | Arylesterase | |
| 178748 | zmp-3 | Matrix metalloproteinase-C | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180351 | W01F3.2 | Uncharacterized protein | |
| 187297 | poml-1 | PON (paraoxonase) and MEC-6 Like | |
| 188252 | lev-9 | Protein lev-9 |
