toxic shock syndrome

Summary
Synonym
  • TSS
  • toxic shock
Definition
A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus, which produce toxins that are absorbed systemically and produce the systemic manifestations. The infection has_symptom fever, has_symptom rash, has_symptom hypotension, has_symptom multiorgan failure, has_symptom desquamation, has_symptom vomiting, has_symptom diarrhea, has_symptom headache, and has_symptom nonfocal neurologic abnormalities.
Super Class
commensal bacterial infectious disease
Disease Ontology
DOID:14115
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
WikiPathways (from TogoID)
Related Genes
Displaying entries 11 - 12 of 12 in total
Gene ID Gene Symbol Description Source
6439 SFTPB surfactant protein B
7035 TFPI tissue factor pathway inhibitor
Displaying all 2 entries
Gene ID Gene Symbol Description Source
24153 A2m alpha-2-macroglobulin
24816 Tbxa2r thromboxane A2 receptor

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025