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Standards Ontologies Notations
Guidelines
MIRAGE
Parkinson's disease

Summary
Synonym
  • Parkinson disease
  • paralysis agitans
Definition
A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.
Super Class
synucleinopathy
Disease Ontology
DOID:14330
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 41 - 46 of 46 in total
Gene ID Gene Symbol Description Source
23435 TARDBP TAR DNA binding protein
25793 FBXO7 F-box protein 7
26058 GIGYF2 GRB10 interacting GYF protein 2
65018 PINK1 PTEN induced kinase 1
119391 GSTO2 glutathione S-transferase omega 2
120892 LRRK2 leucine rich repeat kinase 2
Displaying all 7 entries
Gene ID Gene Symbol Description Source
11529 Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
13489 Drd2 dopamine receptor D2
19017 Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
74244 Atg7 autophagy related 7
140492 Kcnn2 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
224129 Adcy5 adenylate cyclase 5
225583 Minar2 membrane integral NOTCH2 associated receptor 2
Displaying all 8 entries
Gene ID Gene Symbol Description Source
24473 Htr1a 5-hydroxytryptamine receptor 1A
25085 Th tyrosine hydroxylase
25549 Slc18a2 solute carrier family 18 member A2
25608 Lep leptin
25718 Igf1r insulin-like growth factor 1 receptor
29219 Snca synuclein alpha
84027 Gsk3b glycogen synthase kinase 3 beta
114243 Nox1 NADPH oxidase 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
33461 Pgk Phosphoglycerate kinase
Displaying all 5 entries
Gene ID Gene Symbol Description Source
174274 ptc-1 Protein patched homolog 1;SSD domain-containing protein
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
179347 dop-2 Dopamine receptor 2
180747 glit-1 Neuroligin-like protein glit-1
Displaying all 2 entries
Gene ID Gene Symbol Description Source
853071 TIF4631 translation initiation factor eIF4G
855552 PSD1 phosphatidylserine decarboxylase 1
Related Glycoprotein
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025