major depressive disorder

Summary
Synonym
  • clinical depression
  • major depression
  • recurrent major depression
  • single major depressive episode
  • unipolar depression
Definition
A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.
Super Class
depressive disorder
External Links
Disease Ontology
DOID:1470
Mondo Disease Ontology
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 31 - 40 of 217 in total
Gene ID Gene Symbol Description Source
1116 CHI3L1 chitinase 3 like 1
1298 COL9A2 collagen type IX alpha 2 chain
1312 COMT catechol-O-methyltransferase
1374 CPT1A carnitine palmitoyltransferase 1A
1431 CS citrate synthase
1463 NCAN neurocan
1464 CSPG4 chondroitin sulfate proteoglycan 4
1544 CYP1A2 cytochrome P450 family 1 subfamily A member 2
1555 CYP2B6 cytochrome P450 family 2 subfamily B member 6
1557 CYP2C19 cytochrome P450 family 2 subfamily C member 19
Displaying 1 entry
Gene ID Gene Symbol Description Source
15558 Htr2a 5-hydroxytryptamine (serotonin) receptor 2A
Displaying 1 entry
Gene ID Gene Symbol Description Source
29595 Htr2a 5-hydroxytryptamine receptor 2A

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Last updated: August 19, 2024