major depressive disorder

Summary
Synonym
  • clinical depression
  • major depression
  • recurrent major depression
  • single major depressive episode
  • unipolar depression
Definition
A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.
Super Class
depressive disorder
External Links
Disease Ontology
DOID:1470
Mondo Disease Ontology
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 41 - 50 of 217 in total
Gene ID Gene Symbol Description Source
1559 CYP2C9 cytochrome P450 family 2 subfamily C member 9
1571 CYP2E1 cytochrome P450 family 2 subfamily E member 1
1576 CYP3A4 cytochrome P450 family 3 subfamily A member 4
1586 CYP17A1 cytochrome P450 family 17 subfamily A member 1
1588 CYP19A1 cytochrome P450 family 19 subfamily A member 1
1589 CYP21A2 cytochrome P450 family 21 subfamily A member 2
1593 CYP27A1 cytochrome P450 family 27 subfamily A member 1
1605 DAG1 dystroglycan 1
1607 DGKB diacylglycerol kinase beta
1608 DGKG diacylglycerol kinase gamma
Displaying 1 entry
Gene ID Gene Symbol Description Source
15558 Htr2a 5-hydroxytryptamine (serotonin) receptor 2A
Displaying 1 entry
Gene ID Gene Symbol Description Source
29595 Htr2a 5-hydroxytryptamine receptor 2A

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Last updated: August 19, 2024