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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
multiple sclerosis
Summary
- Synonym
-
- Generalized multiple sclerosis
- insular sclerosis
- Definition
- A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.
- Super Class
- autoimmune disease of central nervous system demyelinating disease
External Links
- Disease Ontology
- DOID:2377
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- GARD
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 1508 | CTSB | cathepsin B | |
| 1906 | EDN1 | endothelin 1 | |
| 2212 | FCGR2A | Fc gamma receptor IIa | |
| 2214 | FCGR3A | Fc gamma receptor IIIa | |
| 2556 | GABRA3 | gamma-aminobutyric acid type A receptor subunit alpha3 | |
| 2638 | GC | GC vitamin D binding protein | |
| 2735 | GLI1 | GLI family zinc finger 1 | |
| 2896 | GRN | granulin precursor | |
| 2918 | GRM8 | glutamate metabotropic receptor 8 | |
| 3065 | HDAC1 | histone deacetylase 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 20296 | Ccl2 | C-C motif chemokine ligand 2 | |
| 20306 | Ccl7 | C-C motif chemokine ligand 7 | |
| 20423 | Shh | sonic hedgehog | |
| 20750 | Spp1 | secreted phosphoprotein 1 | |
| 21898 | Tlr4 | toll-like receptor 4 | |
| 21926 | Tnf | tumor necrosis factor | |
| 21937 | Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | |
| 21939 | Cd40 | CD40 antigen | |
| 21950 | Tnfsf9 | tumor necrosis factor (ligand) superfamily, member 9 | |
| 27056 | Irf5 | interferon regulatory factor 5 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24153 | A2m | alpha-2-macroglobulin | |
| 24179 | Agt | angiotensinogen | |
| 24225 | Bdnf | brain-derived neurotrophic factor | |
| 24481 | Ifnb1 | interferon beta 1 | |
| 24483 | Igf2 | insulin-like growth factor 2 | |
| 24596 | Ngfr | nerve growth factor receptor | |
| 24699 | Ptprc | protein tyrosine phosphatase, receptor type, C | |
| 24770 | Ccl2 | C-C motif chemokine ligand 2 | |
| 24835 | Tnf | tumor necrosis factor | |
| 24947 | Gabra3 | gamma-aminobutyric acid type A receptor subunit alpha 3 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 32158 | cac | cacophony | |
| 36585 | beta4GalNAcTA | beta1,4-N-acetylgalactosaminyltransferase A | |
| 39443 | Ptp69D | Protein tyrosine phosphatase 69D | |
| 39984 | Grd | Glycine receptor | |
| 41625 | Ace | Acetylcholine esterase | |
| 41840 | Hsc70-4 | Heat shock protein 70 cognate 4 | |
| 42490 | Mvl | Malvolio | |
| 43222 | Tl | Toll | |
| 43275 | Ser | Serrate | |
| 43425 | beta4GalNAcTB | beta1,4-N-acetylgalactosaminyltransferase B |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 114549 | ache | acetylcholinesterase (Yt blood group) | |
| 140421 | jag1a | jagged canonical Notch ligand 1a | |
| 393912 | b4galt6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | |
| 406411 | rhoaa | ras homolog gene family, member Aa | |
| 406659 | rhoac | ras homolog gene family, member Ac | |
| 555941 | cacna1ba | calcium channel, voltage-dependent, N type, alpha 1B subunit, a | |
| 724080 | b4galt5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | |
| 100006041 | rhoab | ras homolog gene family, member Ab |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 446703 | b4galt5.L | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 L homeolog | Xenopus laevis (African clawed frog) | |
| 548965 | b4galt6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | Xenopus tropicalis (tropical clawed frog) | |
| 549139 | b4galt5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | Xenopus tropicalis (tropical clawed frog) | |
| 779435 | b4galt6.L | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 L homeolog | Xenopus laevis (African clawed frog) | |
| 108695277 | b4galt6.S | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 S homeolog | Xenopus laevis (African clawed frog) | |
| 108702589 | b4galt5.S | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 180351 | W01F3.2 | Uncharacterized protein | |
| 180638 | wrt-6 | Warthog protein 6 N-product | |
| 180931 | cpr-6 | Cathepsin B-like cysteine proteinase 6 | |
| 180939 | smf-1 | NRAMP-like transporter smf-1 | |
| 181706 | ace-1 | Acetylcholinesterase 1 | |
| 190602 | drag-1 | Repulsive guidance molecule B homolog drag-1 | |
| 190668 | bre-4 | Beta-1,4-N-acetylgalactosaminyltransferase bre-4 | |
| 191707 | mgl-1 | G-protein coupled receptors family 3 profile domain-containing protein;putative metabotropic glutamate receptor mgl-1 | |
| 191766 | smf-2 | NRAMP-like transporter smf-2 | |
| 3565419 | clr-1 | Receptor-type tyrosine-protein phosphatase;protein-tyrosine-phosphatase |
