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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
multiple sclerosis
Summary
- Synonym
-
- Generalized multiple sclerosis
- insular sclerosis
- Definition
- A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.
- Super Class
- autoimmune disease of central nervous system demyelinating disease
External Links
- Disease Ontology
- DOID:2377
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- GARD
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 7099 | TLR4 | toll like receptor 4 | |
| 7124 | TNF | tumor necrosis factor | |
| 7132 | TNFRSF1A | TNF receptor superfamily member 1A | |
| 7941 | PLA2G7 | phospholipase A2 group VII | |
| 9331 | B4GALT6 | beta-1,4-galactosyltransferase 6 | |
| 9334 | B4GALT5 | beta-1,4-galactosyltransferase 5 | |
| 9370 | ADIPOQ | adiponectin, C1Q and collagen domain containing | |
| 9563 | H6PD | hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase | |
| 9749 | PHACTR2 | phosphatase and actin regulator 2 | |
| 10198 | MPHOSPH9 | M-phase phosphoprotein 9 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11423 | Ache | acetylcholinesterase | |
| 11450 | Adipoq | adiponectin, C1Q and collagen domain containing | |
| 11595 | Acan | aggrecan | |
| 11596 | Ager | advanced glycosylation end product-specific receptor | |
| 12064 | Bdnf | brain derived neurotrophic factor | |
| 12287 | Cacna1b | calcium channel, voltage-dependent, N type, alpha 1B subunit | |
| 12477 | Ctla4 | cytotoxic T-lymphocyte-associated protein 4 | |
| 12484 | Cd24a | CD24a antigen | |
| 12487 | Cd28 | CD28 antigen | |
| 12524 | Cd86 | CD86 antigen |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 29146 | Jag1 | jagged canonical Notch ligand 1 | |
| 29260 | Tlr4 | toll-like receptor 4 | |
| 29333 | Cd46 | CD46 molecule | |
| 29393 | Col1a1 | collagen type I alpha 1 chain | |
| 29409 | Mag | myelin-associated glycoprotein | |
| 29499 | Shh | sonic hedgehog signaling molecule | |
| 58968 | Acan | aggrecan | |
| 60590 | Grm8 | glutamate metabotropic receptor 8 | |
| 65196 | B4galt6 | beta-1,4-galactosyltransferase 6 | |
| 81687 | Mmp9 | matrix metallopeptidase 9 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 32158 | cac | cacophony | |
| 36585 | beta4GalNAcTA | beta1,4-N-acetylgalactosaminyltransferase A | |
| 39443 | Ptp69D | Protein tyrosine phosphatase 69D | |
| 39984 | Grd | Glycine receptor | |
| 41625 | Ace | Acetylcholine esterase | |
| 41840 | Hsc70-4 | Heat shock protein 70 cognate 4 | |
| 42490 | Mvl | Malvolio | |
| 43222 | Tl | Toll | |
| 43275 | Ser | Serrate | |
| 43425 | beta4GalNAcTB | beta1,4-N-acetylgalactosaminyltransferase B |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 114549 | ache | acetylcholinesterase (Yt blood group) | |
| 140421 | jag1a | jagged canonical Notch ligand 1a | |
| 393912 | b4galt6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | |
| 406411 | rhoaa | ras homolog gene family, member Aa | |
| 406659 | rhoac | ras homolog gene family, member Ac | |
| 555941 | cacna1ba | calcium channel, voltage-dependent, N type, alpha 1B subunit, a | |
| 724080 | b4galt5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | |
| 100006041 | rhoab | ras homolog gene family, member Ab |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 446703 | b4galt5.L | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 L homeolog | Xenopus laevis (African clawed frog) | |
| 548965 | b4galt6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | Xenopus tropicalis (tropical clawed frog) | |
| 549139 | b4galt5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | Xenopus tropicalis (tropical clawed frog) | |
| 779435 | b4galt6.L | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 L homeolog | Xenopus laevis (African clawed frog) | |
| 108695277 | b4galt6.S | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 S homeolog | Xenopus laevis (African clawed frog) | |
| 108702589 | b4galt5.S | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 180351 | W01F3.2 | Uncharacterized protein | |
| 180638 | wrt-6 | Warthog protein 6 N-product | |
| 180931 | cpr-6 | Cathepsin B-like cysteine proteinase 6 | |
| 180939 | smf-1 | NRAMP-like transporter smf-1 | |
| 181706 | ace-1 | Acetylcholinesterase 1 | |
| 190602 | drag-1 | Repulsive guidance molecule B homolog drag-1 | |
| 190668 | bre-4 | Beta-1,4-N-acetylgalactosaminyltransferase bre-4 | |
| 191707 | mgl-1 | G-protein coupled receptors family 3 profile domain-containing protein;putative metabotropic glutamate receptor mgl-1 | |
| 191766 | smf-2 | NRAMP-like transporter smf-2 | |
| 3565419 | clr-1 | Receptor-type tyrosine-protein phosphatase;protein-tyrosine-phosphatase |
