multiple sclerosis

Summary
Synonym
  • Generalized multiple sclerosis
  • insular sclerosis
Definition
A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.
Super Class
autoimmune disease of central nervous system demyelinating disease
Disease Ontology
DOID:2377
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 41 - 50 of 55 in total
Gene ID Gene Symbol Description Source
6347 CCL2 C-C motif chemokine ligand 2
6354 CCL7 C-C motif chemokine ligand 7
6556 SLC11A1 solute carrier family 11 member 1
6696 SPP1 secreted phosphoprotein 1
7124 TNF tumor necrosis factor
7132 TNFRSF1A TNF receptor superfamily member 1A
9563 H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase
9749 PHACTR2 phosphatase and actin regulator 2
10198 MPHOSPH9 M-phase phosphoprotein 9
23095 KIF1B kinesin family member 1B
Displaying all 2 entries
Gene ID Gene Symbol Description Source
18646 Prf1 perforin 1 (pore forming protein)
21926 Tnf tumor necrosis factor

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Last updated: August 4, 2025