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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
asthma
Summary
- Synonym
-
- bronchial hyperreactivity
- chronic obstructive asthma
- chronic obstructive asthma with acute exacerbation
- chronic obstructive asthma with status asthmaticus
- Definition
- A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
- Super Class
- bronchial disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 4586 | MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | |
| 4589 | MUC7 | mucin 7, secreted | |
| 4638 | MYLK | myosin light chain kinase | |
| 4780 | NFE2L2 | NFE2 like bZIP transcription factor 2 | |
| 4803 | NGF | nerve growth factor | |
| 4842 | NOS1 | nitric oxide synthase 1 | |
| 4843 | NOS2 | nitric oxide synthase 2 | |
| 4846 | NOS3 | nitric oxide synthase 3 | |
| 4908 | NTF3 | neurotrophin 3 | |
| 4914 | NTRK1 | neurotrophic receptor tyrosine kinase 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 16190 | Il4ra | interleukin 4 receptor, alpha | |
| 16191 | Il5 | interleukin 5 | |
| 16192 | Il5ra | interleukin 5 receptor, alpha | |
| 16198 | Il9 | interleukin 9 | |
| 16199 | Il9r | interleukin 9 receptor | |
| 16416 | Itgb3 | integrin beta 3 | |
| 16420 | Itgb6 | integrin beta 6 | |
| 16438 | Itpr1 | inositol 1,4,5-trisphosphate receptor 1 | |
| 16542 | Kdr | kinase insert domain protein receptor | |
| 16846 | Lep | leptin |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24180 | Agtr1a | angiotensin II receptor, type 1a | |
| 24182 | Agtr2 | angiotensin II receptor, type 2 | |
| 24225 | Bdnf | brain-derived neurotrophic factor | |
| 24232 | C3 | complement C3 | |
| 24255 | Cftr | CF transmembrane conductance regulator | |
| 24260 | Chrm3 | cholinergic receptor, muscarinic 3 | |
| 24310 | Ace | angiotensin I converting enzyme | |
| 24464 | Hp | haptoglobin | |
| 24493 | Il1a | interleukin 1 alpha | |
| 24598 | Nos1 | nitric oxide synthase 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31926 | Idgf4 | Imaginal disc growth factor 4 | |
| 34091 | Spn28Dc | Serpin 28Dc | |
| 34189 | Acer | Angiotensin-converting enzyme-related | |
| 34805 | Ance | Angiotensin converting enzyme | |
| 34978 | Idgf1 | Imaginal disc growth factor 1 | |
| 34979 | Idgf2 | Imaginal disc growth factor 2 | |
| 34981 | Idgf3 | Imaginal disc growth factor 3 | |
| 35334 | CarT | Carcinine transporter | |
| 36417 | Balat | Beta-alanine transporter | |
| 36428 | Mdr49 | Multi drug resistance 49 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30682 | vegfaa | vascular endothelial growth factor Aa | |
| 58133 | ngfb | nerve growth factor b (beta polypeptide) | |
| 114424 | cdh1 | cadherin 1, type 1, E-cadherin (epithelial) | |
| 387303 | gbgt1l4 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4 | |
| 394082 | slc18a3b | solute carrier family 18 member 3b | |
| 406411 | rhoaa | ras homolog gene family, member Aa | |
| 406659 | rhoac | ras homolog gene family, member Ac | |
| 436718 | rhocb | ras homolog family member Cb | |
| 447881 | gbgt1l3 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3 | |
| 554230 | kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 100497509 | abo.4 | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 | Xenopus tropicalis (tropical clawed frog) | |
| 108698211 | abo.2.L | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 L homeolog | Xenopus laevis (African clawed frog) | |
| 108698863 | abo.4.L | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 L homeolog | Xenopus laevis (African clawed frog) | |
| 108709389 | ngf.S | nerve growth factor S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 172841 | 45566 | Organic cation transporter 1 | |
| 174044 | sma-6 | Serine/threonine-protein kinase receptor sma-6 | |
| 174462 | let-23 | Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase | |
| 175182 | ver-1 | Protein ver-1 | |
| 175383 | zmp-2 | Matrix metalloproteinase-B | |
| 175504 | pat-3 | Integrin beta pat-3 | |
| 177343 | skn-1 | BZIP domain-containing protein;Protein skinhead-1 | |
| 178118 | trpa-1 | Ion transport domain-containing protein;Transient receptor potential cation channel subfamily A member 1 homolog | |
| 178215 | pgp-1 | Multidrug resistance protein pgp-1 | |
| 178274 | cho-1 | High-affinity choline transporter 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850462 | GIT1 | Git1p | |
| 851171 | HMG2 | hydroxymethylglutaryl-CoA reductase (NADPH) HMG2 | |
| 851977 | CTS2 | putative chitinase | |
| 853671 | STE6 | ATP-binding cassette a-factor transporter STE6 | |
| 853978 | NFT1 | putative multidrug transporter NFT1 | |
| 854394 | STE13 | Ste13p | |
| 854900 | HMG1 | hydroxymethylglutaryl-CoA reductase (NADPH) HMG1 | |
| 856294 | RHO1 | Rho family GTPase RHO1 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001426 | Non-Mendelian inheritance |
| HP:0000006 | Autosomal dominant inheritance |
| HP:0002099 | Asthma |
