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MIRAGE
asthma

Summary
Synonym
  • bronchial hyperreactivity
  • chronic obstructive asthma
  • chronic obstructive asthma with acute exacerbation
  • chronic obstructive asthma with status asthmaticus
Definition
A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
Super Class
bronchial disease
Disease Ontology
DOID:2841
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 41 - 50 of 130 in total
Gene ID Gene Symbol Description Source
2908 NR3C1 nuclear receptor subfamily 3 group C member 1
3106 HLA-B major histocompatibility complex, class I, B
3113 HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
3115 HLA-DPB1 major histocompatibility complex, class II, DP beta 1
3117 HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
3118 HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
3119 HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
3122 HLA-DRA major histocompatibility complex, class II, DR alpha
3123 HLA-DRB1 major histocompatibility complex, class II, DR beta 1
3125 HLA-DRB3 major histocompatibility complex, class II, DR beta 3
Displaying all 2 entries
Gene ID Gene Symbol Description Source
16190 Il4ra interleukin 4 receptor, alpha
16420 Itgb6 integrin beta 6
Displaying entries 11 - 12 of 12 in total
Gene ID Gene Symbol Description Source
260320 F7 coagulation factor VII
312896 Trpa1 transient receptor potential cation channel, subfamily A, member 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
40404 ORMDL Orosomucoid 1-like
Related Glycoprotein
Displaying 1 entry
UniProt ID Protein Name Source
Q9VP04 ORM1-like protein
The Human Phenotype Ontology
Displaying all 3 entries
HPO ID HPO Term
HP:0000006 Autosomal dominant inheritance
HP:0001426 Non-Mendelian inheritance
HP:0002099 Asthma
Displaying 1 entry
Gene ID Gene Symbol Description
240 ALOX5 arachidonate 5-lipoxygenase
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025