human immunodeficiency virus infectious disease

Summary
Synonym
  • HIV infection
Definition
A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.
Super Class
viral infectious disease
Disease Ontology
DOID:526
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
WikiPathways (from TogoID)
Related Genes
Displaying entries 51 - 56 of 56 in total
Gene ID Gene Symbol Description Source
50615 IL21R interleukin 21 receptor
54210 TREM1 triggering receptor expressed on myeloid cells 1
55904 KMT2E lysine methyltransferase 2E (inactive)
59067 IL21 interleukin 21
340061 STING1 stimulator of interferon response cGAMP interactor 1
729230 CCR2 C-C motif chemokine receptor 2
Displaying entries 21 - 30 of 62 in total
Gene ID Gene Symbol Description Source
16168 Il15 interleukin 15
16847 Lepr leptin receptor
17195 Mbl2 mannose-binding lectin (protein C) 2
17345 Mki67 antigen identified by monoclonal antibody Ki 67
18039 Nefl neurofilament, light polypeptide
18040 Nefm neurofilament, medium polypeptide
18390 Oprm1 opioid receptor, mu 1
18566 Pdcd1 programmed cell death 1
18646 Prf1 perforin 1 (pore forming protein)
18669 Abcb1b ATP-binding cassette, sub-family B member 1B
Displaying entries 11 - 20 of 25 in total
Gene ID Gene Symbol Description Source
25651 Selp selectin P
25670 Il15 interleukin 15
25712 Ifng interferon gamma
29397 Ccl11 C-C motif chemokine ligand 11
29527 Ptgs2 prostaglandin-endoperoxide synthase 2
50692 Plaur plasminogen activator, urokinase receptor
54258 Cxcr1 C-X-C motif chemokine receptor 1
83613 Nefl neurofilament light chain
84349 Cd40lg CD40 ligand
117029 Ccr5 C-C motif chemokine receptor 5
Displaying all 4 entries
Gene ID Gene Symbol Description Source
34091 Spn28Dc Serpin 28Dc
36016 Sting sting
36428 Mdr49 Multi drug resistance 49
38726 Mdr65 Multi drug resistance 65
Displaying all 4 entries
Gene ID Gene Symbol Description Source
173794 vab-1 Ephrin receptor 1
178215 pgp-1 Multidrug resistance protein pgp-1
181326 pgp-3 Multidrug resistance protein pgp-3
188252 lev-9 Protein lev-9
Displaying all 2 entries
Gene ID Gene Symbol Description Source
851665 RLI1 Fe-S cluster-binding ribosome biosynthesis protein
853671 STE6 ATP-binding cassette a-factor transporter STE6

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Last updated: December 9, 2024