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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
lung disease
Summary
- Definition
- A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.
- Super Class
- lower respiratory tract disease
External Links
- Disease Ontology
- DOID:850
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 6441 | SFTPD | surfactant protein D | |
| 6900 | CNTN2 | contactin 2 | |
| 7040 | TGFB1 | transforming growth factor beta 1 | |
| 7097 | TLR2 | toll like receptor 2 | |
| 7099 | TLR4 | toll like receptor 4 | |
| 7124 | TNF | tumor necrosis factor | |
| 8809 | IL18R1 | interleukin 18 receptor 1 | |
| 10097 | ACTR2 | actin related protein 2 | |
| 59272 | ACE2 | angiotensin converting enzyme 2 | |
| 653509 | SFTPA1 | surfactant protein A1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 16183 | Il2 | interleukin 2 | |
| 17395 | Mmp9 | matrix metallopeptidase 9 | |
| 17523 | Mpo | myeloperoxidase | |
| 17829 | Muc1 | mucin 1, transmembrane | |
| 18127 | Nos3 | nitric oxide synthase 3, endothelial cell | |
| 20296 | Ccl2 | C-C motif chemokine ligand 2 | |
| 20388 | Sftpb | surfactant associated protein B | |
| 20390 | Sftpd | surfactant associated protein D | |
| 21367 | Cntn2 | contactin 2 | |
| 21803 | Tgfb1 | transforming growth factor, beta 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24255 | Cftr | CF transmembrane conductance regulator | |
| 24310 | Ace | angiotensin I converting enzyme | |
| 24326 | Ednra | endothelin receptor type A | |
| 24493 | Il1a | interleukin 1 alpha | |
| 24600 | Nos3 | nitric oxide synthase 3 | |
| 24617 | Serpine1 | serpin family E member 1 | |
| 24770 | Ccl2 | C-C motif chemokine ligand 2 | |
| 24773 | Sftpa1 | surfactant protein A1 | |
| 24835 | Tnf | tumor necrosis factor | |
| 25245 | Bdkrb2 | bradykinin receptor B2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 173828 | rig-6 | Contactin rig-6 | |
| 174462 | let-23 | Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase | |
| 175383 | zmp-2 | Matrix metalloproteinase-B | |
| 178672 | srp-3 | Serpin domain-containing protein | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180351 | W01F3.2 | Uncharacterized protein | |
| 180780 | acn-1 | Inactive angiotensin-converting enzyme-related protein | |
| 180841 | gnrr-4 | G-protein coupled receptors family 1 profile domain-containing protein | |
| 181178 | gpx-5 | Glutathione peroxidase | |
| 181288 | pxn-2 | Peroxidasin homolog pxn-2 |
