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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
diabetes mellitus
Summary
- Synonym
-
- diabetes
- Definition
- A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.
- Super Class
- glucose metabolism disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 4314 | MMP3 | matrix metallopeptidase 3 | |
| 4879 | NPPB | natriuretic peptide B | |
| 5054 | SERPINE1 | serpin family E member 1 | |
| 5465 | PPARA | peroxisome proliferator activated receptor alpha | |
| 5728 | PTEN | phosphatase and tensin homolog | |
| 5770 | PTPN1 | protein tyrosine phosphatase non-receptor type 1 | |
| 5789 | PTPRD | protein tyrosine phosphatase receptor type D | |
| 5798 | PTPRN | protein tyrosine phosphatase receptor type N | |
| 5799 | PTPRN2 | protein tyrosine phosphatase receptor type N2 | |
| 6352 | CCL5 | C-C motif chemokine ligand 5 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 16971 | Lrp1 | low density lipoprotein receptor-related protein 1 | |
| 17187 | Max | Max protein | |
| 18609 | Pdx1 | pancreatic and duodenal homeobox 1 | |
| 19013 | Ppara | peroxisome proliferator activated receptor alpha | |
| 19126 | Prom1 | prominin 1 | |
| 19266 | Ptprd | protein tyrosine phosphatase receptor type D | |
| 19276 | Ptprn2 | protein tyrosine phosphatase receptor type N polypeptide 2 | |
| 20415 | Shbg | sex hormone binding globulin | |
| 20521 | Slc22a12 | solute carrier family 22 (organic anion/cation transporter), member 12 | |
| 20525 | Slc2a1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24255 | Cftr | CF transmembrane conductance regulator | |
| 24296 | Cyp1a1 | cytochrome P450, family 1, subfamily a, polypeptide 1 | |
| 24375 | Fuca1 | alpha-L-fucosidase 1 | |
| 24377 | G6pd | glucose-6-phosphate dehydrogenase | |
| 24385 | Gck | glucokinase | |
| 24446 | Hgf | hepatocyte growth factor | |
| 24464 | Hp | haptoglobin | |
| 24505 | Ins1 | insulin 1 | |
| 24506 | Ins2 | insulin 2 | |
| 24617 | Serpine1 | serpin family E member 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30262 | ins | preproinsulin | |
| 64274 | csf1ra | colony stimulating factor 1 receptor, a | |
| 114424 | cdh1 | cadherin 1, type 1, E-cadherin (epithelial) | |
| 322857 | prom1a | prominin 1a | |
| 337685 | ogt.1 | O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1 | |
| 559080 | cftr | CF transmembrane conductance regulator |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 378695 | ins.L | insulin L homeolog | Xenopus laevis (African clawed frog) | |
| 378696 | ins.S | insulin S homeolog | Xenopus laevis (African clawed frog) | |
| 397750 | hmgcr.L | 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog | Xenopus laevis (African clawed frog) | |
| 397778 | tgfb1.L | transforming growth factor beta 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 398006 | insr.L | insulin receptor L homeolog | Xenopus laevis (African clawed frog) | |
| 398022 | igf1r.S | insulin like growth factor 1 receptor S homeolog | Xenopus laevis (African clawed frog) | |
| 553157 | ogt | O-linked N-acetylglucosamine (GlcNAc) transferase | Xenopus tropicalis (tropical clawed frog) | |
| 100337618 | cdh1.S | cadherin 1, type 1 S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 171619 | C53D5.5 | Gamma-glutamyltranspeptidase 1 | |
| 174462 | let-23 | Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase | |
| 174685 | ptp-3 | Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase | |
| 175410 | daf-2 | Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase | |
| 175807 | ida-1 | Receptor-type tyrosine-protein phosphatase-like ida-1 | |
| 176000 | ogt-1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase;protein O-GlcNAc transferase | |
| 178046 | gspd-1 | Glucose-6-phosphate 1-dehydrogenase | |
| 178748 | zmp-3 | Matrix metalloproteinase-C | |
| 179053 | cpr-4 | Cathepsin B-like cysteine proteinase 4 | |
| 179197 | cri-2 | Putative metalloproteinase inhibitor tag-225 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850317 | GLK1 | glucokinase | |
| 850369 | ADP1 | putative ATP-dependent permease ADP1 | |
| 850462 | GIT1 | Git1p | |
| 850614 | HXK1 | hexokinase 1 | |
| 851006 | ECM38 | gamma-glutamyltransferase | |
| 851171 | HMG2 | hydroxymethylglutaryl-CoA reductase (NADPH) HMG2 | |
| 852128 | EMI2 | putative glucokinase | |
| 852543 | VVS1 | Vvs1p | |
| 852639 | HXK2 | hexokinase 2 | |
| 853978 | NFT1 | putative multidrug transporter NFT1 |
