diabetes mellitus

Summary
Synonym
  • diabetes
Definition
A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.
Super Class
glucose metabolism disease
Disease Ontology
DOID:9351
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 84 in total
Gene ID Gene Symbol Description Source
177 AGER advanced glycosylation end-product specific receptor
338 APOB apolipoprotein B
344 APOC2 apolipoprotein C2
345 APOC3 apolipoprotein C3
348 APOE apolipoprotein E
350 APOH apolipoprotein H
358 AQP1 aquaporin 1 (Colton blood group)
361 AQP4 aquaporin 4
406 BMAL1 basic helix-loop-helix ARNT like 1
653 BMP5 bone morphogenetic protein 5
Displaying entries 1 - 10 of 72 in total
Gene ID Gene Symbol Description Source
11596 Ager advanced glycosylation end product-specific receptor
11814 Apoc3 apolipoprotein C-III
11818 Apoh apolipoprotein H
11826 Aqp1 aquaporin 1
11829 Aqp4 aquaporin 4
12160 Bmp5 bone morphogenetic protein 5
12161 Bmp6 bone morphogenetic protein 6
12162 Bmp7 bone morphogenetic protein 7
12163 Bmp8a bone morphogenetic protein 8a
12164 Bmp8b bone morphogenetic protein 8b
Displaying entries 21 - 30 of 46 in total
Gene ID Gene Symbol Description Source
25675 Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase
25704 Il2ra interleukin 2 receptor subunit alpha
25718 Igf1r insulin-like growth factor 1 receptor
25747 Ppara peroxisome proliferator activated receptor alpha
26295 Ogt O-linked N-acetylglucosamine (GlcNAc) transferase
29199 Hfe homeostatic iron regulator
29260 Tlr4 toll-like receptor 4
29436 Tfpi tissue factor pathway inhibitor
29535 Pdx1 pancreatic and duodenal homeobox 1
29714 Ptprn2 protein tyrosine phosphatase, receptor type N2
Displaying entry 21 - 21 of 21 in total
Gene ID Gene Symbol Description Source
3772574 Fuca alpha-L-fucosidase
Displaying all 6 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
64274 csf1ra colony stimulating factor 1 receptor, a
114424 cdh1 cadherin 1, type 1, E-cadherin (epithelial)
322857 prom1a prominin 1a
337685 ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
559080 cftr CF transmembrane conductance regulator
Displaying all 8 entries
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
398006 insr.L insulin receptor L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
553157 ogt O-linked N-acetylglucosamine (GlcNAc) transferase Xenopus tropicalis (tropical clawed frog)
100337618 cdh1.S cadherin 1, type 1 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 17 in total
Gene ID Gene Symbol Description Source
171619 C53D5.5 Gamma-glutamyltranspeptidase 1
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
174685 ptp-3 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176000 ogt-1 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase;protein O-GlcNAc transferase
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
178748 zmp-3 Matrix metalloproteinase-C
179053 cpr-4 Cathepsin B-like cysteine proteinase 4
179197 cri-2 Putative metalloproteinase inhibitor tag-225
Displaying entries 11 - 14 of 14 in total
Gene ID Gene Symbol Description Source
854900 HMG1 hydroxymethylglutaryl-CoA reductase (NADPH) HMG1
855480 ZWF1 glucose-6-phosphate dehydrogenase
856014 GLR1 glutathione-disulfide reductase GLR1
856533 ECM14 putative metallocarboxypeptidase

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