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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
steatotic liver disease
Summary
- Synonym
-
- Fatty change of liver
- SLD
- Steatosis of liver
- alcoholic fatty liver
- fatty liver disease
- hepatic lipidosis
- hepatic steatosis
- Definition
- A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.
- Super Class
- lipid storage disease liver disease
External Links
- Disease Ontology
- DOID:9452
- Mondo Disease Ontology
- MeSH
- UMLS
- OMIM
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 3630 | INS | insulin | |
| 3643 | INSR | insulin receptor | |
| 3949 | LDLR | low density lipoprotein receptor | |
| 3952 | LEP | leptin | |
| 3958 | LGALS3 | galectin 3 | |
| 4040 | LRP6 | LDL receptor related protein 6 | |
| 4160 | MC4R | melanocortin 4 receptor | |
| 4306 | NR3C2 | nuclear receptor subfamily 3 group C member 2 | |
| 4790 | NFKB1 | nuclear factor kappa B subunit 1 | |
| 4976 | OPA1 | OPA1 mitochondrial dynamin like GTPase |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 22228 | Ucp2 | uncoupling protein 2 (mitochondrial, proton carrier) | |
| 28250 | Slco1a4 | solute carrier organic anion transporter family, member 1a4 | |
| 50490 | Nox4 | NADPH oxidase 4 | |
| 67800 | Dgat2 | diacylglycerol O-acyltransferase 2 | |
| 76282 | Gpt | glutamic pyruvic transaminase, soluble | |
| 76408 | Abcc3 | ATP-binding cassette, sub-family C member 3 | |
| 93671 | Cd163 | CD163 antigen | |
| 97212 | Hadha | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha | |
| 100705 | Acacb | acetyl-Coenzyme A carboxylase beta | |
| 103988 | Gck | glucokinase |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24385 | Gck | glucokinase | |
| 24505 | Ins1 | insulin 1 | |
| 24506 | Ins2 | insulin 2 | |
| 25303 | Abcc2 | ATP binding cassette subfamily C member 2 | |
| 25325 | Il10 | interleukin 10 | |
| 25586 | Alpl | alkaline phosphatase, biomineralization associated | |
| 25608 | Lep | leptin | |
| 25634 | G6pc1 | glucose-6-phosphatase catalytic subunit 1 | |
| 25635 | Mc4r | melanocortin 4 receptor | |
| 25664 | Pparg | peroxisome proliferator-activated receptor gamma |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 35362 | Mtp | Microsomal triacylglycerol transfer protein | |
| 37028 | ACOX1 | acyl-CoA oxidase 1 | |
| 39954 | Oatp74D | Organic anion transporting polypeptide 74D | |
| 41549 | Octbeta2R | Octopamine beta2 receptor | |
| 42160 | htl | heartless | |
| 42549 | InR | Insulin-like receptor | |
| 43191 | Hex-t2 | Hexokinase testis 2 | |
| 117364 | Hex-t1 | Hexokinase testis 1 |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 378695 | ins.L | insulin L homeolog | Xenopus laevis (African clawed frog) | |
| 378696 | ins.S | insulin S homeolog | Xenopus laevis (African clawed frog) | |
| 395003 | dgat2 | diacylglycerol O-acyltransferase 2 | Xenopus tropicalis (tropical clawed frog) | |
| 397782 | fgfr1.S | fibroblast growth factor receptor 1 S homeolog | Xenopus laevis (African clawed frog) | |
| 399444 | fgfr1.L | fibroblast growth factor receptor 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 548648 | fgfr1 | fibroblast growth factor receptor 1 | Xenopus tropicalis (tropical clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 171619 | C53D5.5 | Gamma-glutamyltranspeptidase 1 | |
| 171782 | abt-2 | ABC transporter domain-containing protein | |
| 174116 | gldi-2 | EGF-like domain-containing protein | |
| 175410 | daf-2 | Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase | |
| 176852 | dsc-4 | Microsomal triglyceride transfer protein homolog | |
| 177940 | egl-21 | Carboxypeptidase E | |
| 179053 | cpr-4 | Cathepsin B-like cysteine proteinase 4 | |
| 180033 | cpr-3 | Cathepsin B-like cysteine proteinase 3 | |
| 180289 | mrp-7 | Multidrug resistance protein mrp-7 | |
| 180364 | T03D8.6 | Gamma-glutamyltransferase;Gamma-glutamyltranspeptidase 1 |
