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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
obesity
Summary
- Definition
- An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
- Super Class
- overnutrition
External Links
- Disease Ontology
- DOID:9970
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- MGI genotype (from TogoID)
-
- 3766125
- 3821619
- 3821616
- 3817475
- 3799316
- 3784993
- 3784991
- 3773447
- 3772367
- 3822317
- 3766122
- 3721145
- 3715252
- 3694548
- 3689720
- 3664551
- 3664276
- 3655835
- 5515728
- 7545554
- 7545550
- 7545546
- 6273993
- 5828524
- 5766495
- 5763310
- 5763241
- 3655832
- 5447549
- 5300906
- 3850836
- 3847120
- 3840234
- 3832410
- 3822318
- 3033164
- 3511746
- 3055585
- 3055584
- 3053798
- 3041643
- 3036853
- 3036852
- 3033165
- 3511747
- 2681522
- 2680503
- 2669229
- 2663736
- 2654708
- 2653295
- 2651886
- 2388265
- 3589409
- 3655811
- 3639781
- 3639355
- 3639354
- 3629805
- 3623749
- 3620067
- 3611807
- 2174793
- 3586756
- 3582615
- 3580003
- 3579026
- 3577766
- 3526863
- 3511748
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 23236 | PLCB1 | phospholipase C beta 1 | |
| 23369 | PUM2 | pumilio RNA binding family member 2 | |
| 23389 | MED13L | mediator complex subunit 13L | |
| 23410 | SIRT3 | sirtuin 3 | |
| 23411 | SIRT1 | sirtuin 1 | |
| 23530 | NNT | nicotinamide nucleotide transhydrogenase | |
| 23654 | PLXNB2 | plexin B2 | |
| 24147 | FJX1 | four-jointed box kinase 1 | |
| 26003 | GORASP2 | golgi reassembly stacking protein 2 | |
| 26354 | GNL3 | G protein nucleolar 3 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11303 | Abca1 | ATP-binding cassette, sub-family A member 1 | |
| 11421 | Ace | angiotensin I converting enzyme | |
| 11450 | Adipoq | adiponectin, C1Q and collagen domain containing | |
| 11520 | Plin2 | perilipin 2 | |
| 11537 | Cfd | complement factor D | |
| 11539 | Adora1 | adenosine A1 receptor | |
| 11555 | Adrb2 | adrenergic receptor, beta 2 | |
| 11556 | Adrb3 | adrenergic receptor, beta 3 | |
| 11596 | Ager | advanced glycosylation end product-specific receptor | |
| 11625 | Ahsg | alpha-2-HS-glycoprotein |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24152 | Asip | agouti signaling protein | |
| 24179 | Agt | angiotensinogen | |
| 24217 | Atp4b | ATPase H+/K+ transporting subunit beta | |
| 24225 | Bdnf | brain-derived neurotrophic factor | |
| 24232 | C3 | complement C3 | |
| 24267 | Comt | catechol-O-methyltransferase | |
| 24310 | Ace | angiotensin I converting enzyme | |
| 24318 | Drd2 | dopamine receptor D2 | |
| 24367 | Fgg | fibrinogen gamma chain | |
| 24377 | G6pd | glucose-6-phosphate dehydrogenase |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31002 | Appl | beta amyloid protein precursor-like | |
| 31017 | sdk | sidekick | |
| 31234 | Pdfr | Pigment-dispersing factor receptor | |
| 31293 | N | Notch | |
| 32545 | Gapdh2 | Glyceraldehyde 3 phosphate dehydrogenase 2 | |
| 32556 | Stim | Stromal interaction molecule | |
| 32974 | Zw | Zwischenferment | |
| 33007 | Dop2R | Dopamine 2-like receptor | |
| 33245 | ds | dachsous | |
| 33627 | ft | fat |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30128 | wnt1 | wingless-type MMTV integration site family, member 1 | |
| 30308 | wnt10b | wingless-type MMTV integration site family, member 10b | |
| 30686 | myca | MYC proto-oncogene, bHLH transcription factor a | |
| 30705 | fgfr1a | fibroblast growth factor receptor 1a | |
| 30718 | notch1a | notch receptor 1a | |
| 266751 | adra2b | adrenoceptor alpha 2B | |
| 286833 | mc4r | melanocortin 4 receptor | |
| 317743 | gapdh | glyceraldehyde-3-phosphate dehydrogenase | |
| 393141 | mycb | MYC proto-oncogene, bHLH transcription factor b | |
| 406207 | mttp | microsomal triglyceride transfer protein |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 399444 | fgfr1.L | fibroblast growth factor receptor 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 432172 | akt2.S | v-akt murine thymoma viral oncogene homolog 2 S homeolog | Xenopus laevis (African clawed frog) | |
| 448238 | cadm2 | cell adhesion molecule 2 | Xenopus tropicalis (tropical clawed frog) | |
| 448598 | pon2 | paraoxonase 2 | Xenopus tropicalis (tropical clawed frog) | |
| 494791 | cfd.L | complement factor D L homeolog | Xenopus laevis (African clawed frog) | |
| 548648 | fgfr1 | fibroblast growth factor receptor 1 | Xenopus tropicalis (tropical clawed frog) | |
| 100037842 | notch1 | notch 1 receptor | Xenopus tropicalis (tropical clawed frog) | |
| 100144634 | ace | angiotensin I converting enzyme | Xenopus tropicalis (tropical clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 181684 | cpd-2 | Peptidase M14 carboxypeptidase A domain-containing protein | |
| 181708 | let-2 | Collagen alpha-2(IV) chain | |
| 181720 | C06G1.1 | Lipid-binding serum glycoprotein C-terminal domain-containing protein | |
| 181723 | hda-4 | Histone deacetylase 4 | |
| 182513 | gpx-3 | Glutathione peroxidase 3 | |
| 182726 | nkb-1 | Sodium/potassium-transporting ATPase subunit beta-1 | |
| 183811 | nhx-3 | putative Na(+)/H(+) antiporter nhx-3 | |
| 187297 | poml-1 | PON (paraoxonase) and MEC-6 Like | |
| 188252 | lev-9 | Protein lev-9 | |
| 191374 | dhrr-1 | G_PROTEIN_RECEP_F2_4 domain-containing protein |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850317 | GLK1 | glucokinase | |
| 850391 | NPP1 | nucleotide diphosphatase/phosphodiesterase NPP1 | |
| 850442 | SRB8 | Srb8p | |
| 850614 | HXK1 | hexokinase 1 | |
| 850647 | PUF3 | mRNA-binding protein PUF3 | |
| 851241 | CNE1 | calnexin | |
| 851888 | DPL1 | sphinganine-1-phosphate aldolase DPL1 | |
| 851974 | YPR1 | trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1 | |
| 852053 | SSN2 | Ssn2p | |
| 852102 | IZH1 | PAQR-type receptor |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0010982 | Polygenic inheritance |
| HP:0000006 | Autosomal dominant inheritance |
| HP:0012340 | Decreased resting energy expenditure |
| HP:0001513 | Obesity |
