GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen, GlyConnect, GlycoProtDB and The O-GlcNAc Database. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Source	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	June 4, 2024
The O-GlcNAc Database	June 3, 2024
UniProt	June 4, 2024

Displaying entries **26 - 50** of **213** in total

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UniProt ID	Protein Name ▲	Gene Symbol	Organism	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs	GlyTouCan ID	Disease Ontology	Disease Ontology ID	Gene Ontology	Gene Ontology ID
Q09187	Alpha-galactosidase	MEL	Saccharomyces paradoxus	27291	9	0				alpha-galactosidase activity cytoplasm extracellular region glycoside catabolic process oligosaccharide metabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0009311 GO:0016139
A2BDV6	Alpha-galactosidase (Fragment)	Gla	Mus musculus (house mouse)	10090	1	0				alpha-galactosidase activity cytoplasm glycoside catabolic process oligosaccharide metabolic process	GO:0004557 GO:0005737 GO:0009311 GO:0016139
P04824	Alpha-galactosidase 1	MEL1	Saccharomyces cerevisiae (brewer's yeast)	4932	9	0				alpha-galactosidase activity cytoplasm extracellular region glycoside catabolic process oligosaccharide metabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0009311 GO:0016139
Q9FT97	Alpha-galactosidase 1	AGAL1	Arabidopsis thaliana (thale cress)	3702	2	0				alpha-galactosidase activity apoplast carbohydrate metabolic process cell wall organization plant-type cell wall secretory vesicle	GO:0004557 GO:0005975 GO:0009505 GO:0048046 GO:0071555 GO:0099503
P41945	Alpha-galactosidase 2	MEL2	Saccharomyces cerevisiae (brewer's yeast)	4932	9	0				alpha-galactosidase activity cytoplasm extracellular region glycoside catabolic process oligosaccharide metabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0009311 GO:0016139
Q92457	Alpha-galactosidase 2	agl2	Trichoderma reesei	51453	9	0				alpha-galactosidase activity carbohydrate catabolic process extracellular region	GO:0004557 GO:0005576 GO:0016052
Q8RX86	Alpha-galactosidase 2	AGAL2	Arabidopsis thaliana (thale cress)	3702	3	0				alpha-galactosidase activity apoplast cell wall organization galactomannan catabolic process leaf morphogenesis plant-type cell wall positive regulation of flower development response to fungus secretory vesicle	GO:0004557 GO:0009505 GO:0009620 GO:0009911 GO:0009965 GO:0048046 GO:0051682 GO:0071555 GO:0099503
Q92451	Alpha-galactosidase 3	agl3	Trichoderma reesei	51453	7	0				alpha-galactosidase activity cytoplasm extracellular region glycoside catabolic process oligosaccharide metabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0009311 GO:0016139
Q8VXZ7	Alpha-galactosidase 3	AGAL3	Arabidopsis thaliana (thale cress)	3702	5	0				alpha-galactosidase activity apoplast carbohydrate metabolic process cell wall organization glycoside catabolic process oligosaccharide metabolic process plant-type vacuole secretory vesicle vacuole	GO:0000325 GO:0004557 GO:0005773 GO:0005975 GO:0009311 GO:0016139 GO:0048046 GO:0071555 GO:0099503
P41946	Alpha-galactosidase 5	MEL5	Saccharomyces cerevisiae (brewer's yeast)	4932	8	0				alpha-galactosidase activity cytoplasm extracellular region glycoside catabolic process oligosaccharide metabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0009311 GO:0016139
P41947	Alpha-galactosidase 6	MEL6	Saccharomyces cerevisiae (brewer's yeast)	4932	8	0				alpha-galactosidase activity cytoplasm extracellular region glycoside catabolic process oligosaccharide metabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0009311 GO:0016139
P06280	Alpha-galactosidase A	GLA	Homo sapiens (human)	9606	3	44	G00406II G00912UN G01937VC G05724UK G06110VR G06247RL G11870QZ G12313PD G14669DU G15169WU G23294PN G23719VF G27058EU G28681TP G29184RN G31852PQ G34989PA G37412TK G39188ZX G41247ZX G43669FQ G45395BF G46503DX G47012YE G47644PP G48414YA G49108TO G50282JC G62765YT G62894KT G70101JE G70232NH G72291OX G74724QE G75983OB G76417NN G80920RR G82463GQ G83460ZZ G90382BL G90575OW G92275SC G95995BI G96091TT	Fabry disease Gaucher's disease Goodpasture syndrome Horner's syndrome Laron syndrome Meckel syndrome Moyamoya disease Niemann-Pick disease Parkinson's disease 19A Parkinson's disease 23 Parkinson's disease 4 Parkinson's disease Riley-Day syndrome Takayasu's arteritis X-linked agammaglobulinemia Zollinger-Ellison syndrome achondroplasia acquired hyperkeratosis acute myocardial infarction allergic asthma anemia angiokeratoma anhidrosis antithrombin III deficiency anxiety disorder arthritis arthropathy asthma atrial fibrillation atrioventricular block autosomal dominant polycystic kidney disease bacterial vaginosis breast cancer breast fibrocystic disease brucellosis cancer cardiomyopathy cardiovascular system disease cataract central nervous system origin vertigo cerebral infarction cerebrovascular disease chronic kidney disease chronic obstructive pulmonary disease chylomicron retention disease congenital hypogammaglobulinemia congestive heart failure corneal dystrophy coronary thrombosis cystinuria depressive disorder diabetes insipidus diabetes mellitus diabetic ketoacidosis diarrhea disease of metabolism dysthymic disorder elephantiasis endomyocardial fibrosis epilepsy erythromelalgia essential hypertension familial hyperlipidemia familial hypertrophic cardiomyopathy familial mediterranean fever familial nephrotic syndrome fibromyalgia galactosemia generalized anxiety disorder glaucoma glomerulonephritis glucosephosphate dehydrogenase deficiency glycogen storage disease II glycogen storage disease IXa glycogen storage disease IXb glycogen storage disease IXc glycogen storage disease IXd glycogen storage disease Ia glycogen storage disease granulomatosis with polyangiitis heart disease hyperinsulinism hypertension hypertrophic cardiomyopathy 1 hypertrophic cardiomyopathy hypoglycemia hypohidrosis influenza inherited metabolic disorder interstitial nephritis intrinsic asthma keratosis follicularis kidney disease kidney failure late onset Parkinson's disease lipid storage disease lipoid nephrosis lung disease lymphedema lysosomal storage disease macrocytic anemia major depressive disorder melancholic depression mevalonic aciduria microglandular adenosis mitral valve insufficiency mitral valve prolapse mongolian spot multiple sclerosis myocardial infarction myositis nephritis nephrosis nephrotic syndrome neurohypophyseal diabetes insipidus neuropathy neurotic disorder obsolete melancholia obsolete type 1 diabetes mellitus 9 obstructive lung disease optic atrophy osteoarthritis papillary adenocarcinoma papillary renal cell carcinoma peripheral nervous system disease pneumonia polyarteritis nodosa polyneuropathy priapism protein C deficiency protein S deficiency proteinuria pseudoxanthoma elasticum pyelitis pyelonephritis pyoureter recurrent corneal erosion renal infectious disease sensorineural hearing loss sick sinus syndrome silent myocardial infarction sphingolipidosis thrombophilia thyroid gland papillary carcinoma transient cerebral ischemia tuberculosis type 1 diabetes mellitus 10 type 1 diabetes mellitus 11 type 1 diabetes mellitus 12 type 1 diabetes mellitus 13 type 1 diabetes mellitus 15 type 1 diabetes mellitus 17 type 1 diabetes mellitus 18 type 1 diabetes mellitus 19 type 1 diabetes mellitus 20 type 1 diabetes mellitus 21 type 1 diabetes mellitus 22 type 1 diabetes mellitus 23 type 1 diabetes mellitus 24 type 1 diabetes mellitus 2 type 1 diabetes mellitus 3 type 1 diabetes mellitus 4 type 1 diabetes mellitus 5 type 1 diabetes mellitus 6 type 1 diabetes mellitus 7 type 1 diabetes mellitus 8 type 1 diabetes mellitus type 2 diabetes mellitus uremia vaginitis vascular disease vertebrobasilar insufficiency visual epilepsy vitamin K deficiency bleeding vulvitis vulvovaginal candidiasis vulvovaginitis	DOID:0014667 DOID:0050452 DOID:0050700 DOID:0050778 DOID:0050782 DOID:0050820 DOID:0060224 DOID:0060357 DOID:0060891 DOID:0060892 DOID:0060895 DOID:0060896 DOID:0080326 DOID:0110307 DOID:0110741 DOID:0110742 DOID:0110743 DOID:0110744 DOID:0110745 DOID:0110746 DOID:0110747 DOID:0110748 DOID:0110749 DOID:0110750 DOID:0110751 DOID:0110752 DOID:0110753 DOID:0110754 DOID:0110755 DOID:0110756 DOID:0110757 DOID:0110758 DOID:0110759 DOID:0110760 DOID:0110761 DOID:0111040 DOID:0111041 DOID:0111042 DOID:0111043 DOID:10003 DOID:10354 DOID:1063 DOID:1074 DOID:10763 DOID:10825 DOID:10952 DOID:10966 DOID:11077 DOID:11155 DOID:11156 DOID:11249 DOID:114 DOID:11400 DOID:11486 DOID:11502 DOID:11541 DOID:11589 DOID:1168 DOID:11832 DOID:1184 DOID:11847 DOID:11984 DOID:12132 DOID:12139 DOID:12388 DOID:1287 DOID:12932 DOID:13003 DOID:13072 DOID:13099 DOID:13250 DOID:13884 DOID:1389 DOID:14177 DOID:14179 DOID:1425 DOID:14320 DOID:14330 DOID:14499 DOID:14504 DOID:1470 DOID:1595 DOID:1596 DOID:1612 DOID:162 DOID:1686 DOID:178 DOID:1826 DOID:1837 DOID:1926 DOID:1927 DOID:2018 DOID:2030 DOID:2170 DOID:224 DOID:2272 DOID:2273 DOID:2320 DOID:2355 DOID:2361 DOID:2377 DOID:2451 DOID:2452 DOID:2479 DOID:2508 DOID:2527 DOID:2566 DOID:2590 DOID:2734 DOID:2738 DOID:2744 DOID:2747 DOID:2749 DOID:2752 DOID:2841 DOID:2848 DOID:2862 DOID:2921 DOID:2987 DOID:3083 DOID:3112 DOID:3211 DOID:3385 DOID:3526 DOID:3755 DOID:3756 DOID:381 DOID:3901 DOID:3969 DOID:399 DOID:4465 DOID:4480 DOID:4676 DOID:4702 DOID:479 DOID:4964 DOID:4976 DOID:4977 DOID:552 DOID:557 DOID:5723 DOID:574 DOID:576 DOID:5844 DOID:5854 DOID:5998 DOID:6000 DOID:631 DOID:633 DOID:655 DOID:6713 DOID:782 DOID:784 DOID:83 DOID:8398 DOID:8469 DOID:848 DOID:850 DOID:870 DOID:898 DOID:9240 DOID:9266 DOID:9286 DOID:9351 DOID:9352 DOID:9360 DOID:9408 DOID:9409 DOID:9415 DOID:9455 DOID:9521 DOID:9744 DOID:9808 DOID:9810 DOID:9870 DOID:988 DOID:9993	Golgi apparatus alpha-galactosidase activity azurophil granule lumen catalytic activity cytoplasm extracellular exosome extracellular region galactoside binding glycoside catabolic process glycosphingolipid catabolic process glycosylceramide catabolic process hydrolase activity lysosomal lumen lysosome negative regulation of nitric oxide biosynthetic process negative regulation of nitric-oxide synthase activity oligosaccharide metabolic process protein homodimerization activity signaling receptor binding	GO:0003824 GO:0004557 GO:0005102 GO:0005576 GO:0005737 GO:0005764 GO:0005794 GO:0009311 GO:0016139 GO:0016787 GO:0016936 GO:0035578 GO:0042803 GO:0043202 GO:0045019 GO:0046477 GO:0046479 GO:0051001 GO:0070062
P28351	Alpha-galactosidase A	aglA	Aspergillus niger	5061	7	9	G06110VR G19958IL G39188ZX G55220VL G56960KY G60230HH G65370RS G70101JE G80966KZ			alpha-galactosidase activity carbohydrate binding cytoplasm extracellular region glycoside catabolic process oligosaccharide metabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0009311 GO:0016139 GO:0030246
P51569	Alpha-galactosidase A	Gla Ags	Mus musculus (house mouse)	10090	3	0				Golgi apparatus alpha-galactosidase activity aorta development catalytic activity cytoplasm extracellular region extracellular space galactoside binding glycoside catabolic process glycosylceramide catabolic process hydrolase activity lysosome negative regulation of nitric oxide biosynthetic process negative regulation of nitric-oxide synthase activity oligosaccharide metabolic process protein homodimerization activity signaling receptor binding	GO:0003824 GO:0004557 GO:0005102 GO:0005576 GO:0005615 GO:0005737 GO:0005764 GO:0005794 GO:0009311 GO:0016139 GO:0016787 GO:0016936 GO:0035904 GO:0042803 GO:0045019 GO:0046477 GO:0051001
Q9UUZ4	Alpha-galactosidase C	aglC	Aspergillus niger	5061	10	0				alpha-galactosidase activity carbohydrate catabolic process	GO:0004557 GO:0016052
Q5AU92	Alpha-galactosidase C	aglC	Aspergillus nidulans FGSC A4	227321	8	0				alpha-galactosidase activity extracellular region glycosylation mannan catabolic process	GO:0004557 GO:0005576 GO:0046355 GO:0070085
Q5AX28	Alpha-galactosidase D	aglD	Aspergillus nidulans FGSC A4	227321	9	0				alpha-galactosidase activity cytoplasm extracellular region glycoside catabolic process mannan catabolic process oligosaccharide metabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0009311 GO:0016139 GO:0046355
Q9URZ0	Alpha-galactosidase mel1	mel1	Schizosaccharomyces pombe 972h-	284812	2	0				alpha-galactosidase activity endoplasmic reticulum lumen extracellular region glycoside catabolic process melibiose catabolic process	GO:0004557 GO:0005576 GO:0005788 GO:0005995 GO:0016139
P48842	Arabinogalactan endo-beta-1,4-galactanase	gal1	Aspergillus aculeatus	5053	1	0				arabinogalactan endo-1,4-beta-galactosidase activity glucosidase activity pectin catabolic process	GO:0015926 GO:0031218 GO:0045490
Q5B153	Arabinogalactan endo-beta-1,4-galactanase A	galA	Aspergillus nidulans FGSC A4	227321	1	0				arabinogalactan endo-1,4-beta-galactosidase activity cell wall organization extracellular region glucosidase activity pectin catabolic process	GO:0005576 GO:0015926 GO:0031218 GO:0045490 GO:0071555
Q8X168	Arabinogalactan endo-beta-1,4-galactanase A	galA	Aspergillus niger	5061	1	0				arabinogalactan endo-1,4-beta-galactosidase activity cell wall organization extracellular region glucosidase activity pectin catabolic process	GO:0005576 GO:0015926 GO:0031218 GO:0045490 GO:0071555
O81100	Beta-galactosidase	TBG4	Solanum lycopersicum (tomato)	4081	3	0				beta-galactosidase activity carbohydrate metabolic process vacuole	GO:0004565 GO:0005773 GO:0005975
Q27526	Beta-galactosidase	bgal-1	Caenorhabditis elegans	6239	2	0				beta-galactosidase activity carbohydrate metabolic process vacuole	GO:0004565 GO:0005773 GO:0005975
Q8K131	Beta-galactosidase	Glb1	Mus musculus (house mouse)	10090	1	0				beta-galactosidase activity carbohydrate metabolic process vacuole	GO:0004565 GO:0005773 GO:0005975
Q5R7P4	Beta-galactosidase	GLB1	Pongo abelii (Sumatran orangutan)	9601	6	0				beta-galactosidase activity carbohydrate metabolic process lysosome	GO:0004565 GO:0005764 GO:0005975

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