SMAC (DIABLO) binds to IAPs
|
|
|
- Aipa
- Api3
- Birc4
- Casp7
- Diablo
- Lice2
- Mch3
- Miha
- Smac
- Xiap
|
|
Regulation of PTEN localization
|
|
|
- Aipa
- Api3
- Birc4
- Hausp
- Kiaa0093
- Miha
- Mmac1
- Nedd-4
- Nedd4
- Nedd4-1
- Nedd4a
- Pml
- Pten
- Rpf1
- Rps27a
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
- Usp7
- Xiap
|
|
Purine catabolism
|
|
|
- Airp
- Dnph1
- Dnt1
- Gda
- Itpa
- Np
- Nt5
- Nt5c
- Nt5c1a
- Nt5c1b
- Nt5c2
- Nt5e
- Nte
- Pnp
- Pnp1
- Pnp2
- Xdh
|
|
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
|
|
|
- Ajuba
- Cul2
- Egln1
- Egln2
- Egln3
- Elob
- Eloc
- Epas1
- Hif1a
- Hif2a
- Hif3a
- Jub
- Kiaa0072
- Kiaa0077
- Limd1
- Lmp10
- Lmp19
- Lmp2
- Lmp3
- Lmp7
- Lmpc3
- Mc13
- Mcb1
- Mecl1
- Mmc14
- Mop7
- Mov-34
- Mov34
- Mss1
- Nepas
- P91a
- Pa28b1
- Pad1
- Psma1
- Psma2
- Psma3
- Psma4
- Psma5
- Psma6
- Psma7
- Psma7l
- Psma8
- Psmb1
- Psmb10
- Psmb11
- Psmb2
- Psmb3
- Psmb4
- Psmb5
- Psmb6
- Psmb7
- Psmb8
- Psmb9
- Psmc1
- Psmc2
- Psmc3
- Psmc4
- Psmc5
- Psmc6
- Psmd1
- Psmd10
- Psmd11
- Psmd12
- Psmd13
- Psmd14
- Psmd2
- Psmd3
- Psmd4
- Psmd5
- Psmd6
- Psmd7
- Psmd8
- Psmd9
- Psme1
- Psme2
- Psme3
- Psme4
- Psmf1
- Rbx1
- Ring12
- Rps27a
- Sug1
- Sug2
- Tbp1
- Tbp7
- Tceb1
- Tceb2
- Tstap91a
- Uba52
- Uba80
- Ubb
- Ubc
- Ubc4
- Ubcep1
- Ubcep2
- Ubch4
- Ubch5b
- Ube2d1
- Ube2d2
- Ube2d2a
- Ube2d3
- Vhl
- Vhlh
- Wtip
|
|
Interconversion of nucleotide di- and triphosphates
|
|
|
- Ak-4
- Ak1
- Ak2
- Ak3b
- Ak3l1
- Ak4
- Ak5
- Ak6
- Ak7
- Ak8
- Ak9
- Akd1
- Cinap
- Cmk
- Cmpk
- Cmpk1
- Ctps
- Ctps1
- Ctps2
- Dctd
- Dtymk
- Dut
- Dutp
- Glrx
- Glrx1
- Gmk
- Gr1
- Grx
- Grx1
- Gsr
- Guk1
- Nm23
- Nme1
- Nme2
- Nme3
- Nme4
- Nudt13
- P53r2
- Rrm1
- Rrm2
- Rrm2b
- Tmk
- Trxr1
- Txn
- Txn1
- Txnrd1
- Tyms
- Uck
- Umk
- Umpk
|
|
Factors involved in megakaryocyte development and platelet production
|
|
|
- Ak3
- Ak3l
- Ak3l1
- Akap
- Akap1
- Akap10
- Akl3l
- Aof2
- Aps
- Bhc80
- Braf35
- Cappa1
- Cappa2
- Cappb1
- Capza1
- Capza2
- Capzb
- Carmil
- Carmil1
- Cbx5
- Cdc42
- D12Wsu95e
- D14Wsu89e
- Dock1
- Dock10
- Dock11
- Dock2
- Dock3
- Dock4
- Dock5
- Dock6
- Dock7
- Dock8
- Dock9
- Ehd1
- Ehd2
- Ehd3
- Fog
- Fog1
- Fog2
- Gata-3
- Gata-4
- Gata1
- Gata2
- Gata3
- Gata4
- Gata5
- Gata6
- Gf-1
- Gm430
- H3-143
- H3-3a
- H3-3b
- H3-53
- H3-B
- H3-F
- H3.1-221
- H3.1-291
- H3.1-I
- H3.2
- H3.2-221
- H3.2-614
- H3.2-615
- H3.2-616
- H3.3a
- H3.3b
- H3a
- H3b
- H3c1
- H3c10
- H3c11
- H3c13
- H3c14
- H3c15
- H3c2
- H3c3
- H3c4
- H3c6
- H3c7
- H3c8
- H3f
- H3f3a
- H3f3b
- H3g
- H3h
- H3i
- Hdac1
- Hdac2
- Hist1h3a
- Hist1h3b
- Hist1h3c
- Hist1h3d
- Hist1h3e
- Hist1h3f
- Hist1h3g
- Hist1h3h
- Hist1h3i
- Hist2h3b
- Hist2h3c1
- Hist2h3c2
- Hist2h3ca1
- Hist2h3ca2
- Hmg20b
- Hmgx2
- Hp1a
- Itpk1
- Jak2
- Jhdm2c
- Jmjd1c
- Kdm1a
- Kiaa0071
- Kiaa0214
- Kiaa0601
- Kiaa0694
- Kiaa0716
- Kiaa1058
- Kiaa1380
- Kiaa1395
- Kiaa1696
- Kiaa1771
- Lnk
- Lr2
- Lrrc16
- Lrrc16a
- Lsd1
- Maff
- Mafg
- Mafk
- Marf
- Mfn1
- Mfn2
- Mnlt
- Moca
- Nfe2
- Nfe2u
- Past1
- Pftf1
- Phf21a
- Pkaca
- Pkacb
- Prkaca
- Prkacb
- Prkar1a
- Prkar1b
- Prkar2a
- Rab5a
- Rac1
- Rad51b
- Rad51c
- Rad51l1
- Rad51l2
- Rbsn
- Rcor1
- Rec2
- Rlc
- Sh2b1
- Sh2b2
- Sh2b3
- Sh2bpsm1
- Smarce1r
- Vps45
- Vps45a
- Yy1bp
- Zfpm1
- Zfpm2
- Zfyve20
- Ziz1
- Ziz2
- Ziz3
- nnyRab5a
|
|
Trafficking of AMPA receptors
|
|
|
- Akap150
- Akap5
- Cacng2
- Cacng3
- Cacng4
- Cacng8
- Camk2a
- Camk2b
- Camk2d
- Camk2g
- Dlg1
- Dlg4
- Dlgh1
- Dlgh4
- Epb4
- Epb4.1l1
- Epb41l1
- GluA3
- Glur1
- Glur3
- Glur4
- Gria1
- Gria3
- Gria4
- Kiaa0338
- Kiaa4163
- Kiaa4184
- Mdm2
- Myo6
- Psd95
- Stg
- Sv
|
|
Phase 2 - plateau phase
|
|
|
- Akap9
- Cach2
- Cacn2
- Cacna1c
- Cacna2d2
- Cacnb1
- Cacnb2
- Cacng4
- Cacng6
- Cacng7
- Cacng8
- Cacnl1a1
- Cacnlb1
- Cacnlb2
- Cchl1a1
- Kcna9
- Kcne1l
- Kcne2
- Kcne3
- Kcne4
- Kcne5
- Kcnq1
- Kiaa0558
- Kiaa0803
- Kvlqt1
|
|
Phase 3 - rapid repolarisation
|
|
|
- Akap9
- Erg
- Kcna5
- Kcna9
- Kcne1l
- Kcne2
- Kcne3
- Kcne4
- Kcne5
- Kcnh2
- Kcnq1
- Kiaa0803
- Kvlqt1
- Merg1
|
|
Post-translational modification: synthesis of GPI-anchored proteins
|
|
|
- Akp-2
- Akp-3
- Akp2
- Akp3
- Akp5
- Alpg
- Alpi
- Alpl
- Alppl2
- Art3
- Art4
- Bgp
- Bgp1
- Bgp2
- Bp-3
- Bp3
- Bst1
- C4.4a
- Cd109
- Cd52
- Cdw52
- Ceacam1
- Ceacam2
- Cntn3
- Cntn5
- Cpg15
- Cpg15-2
- Cpm
- Eap
- Fbp2
- Fcgr3a
- Fcgr4
- Folbp2
- Folbp3
- Folr2
- Folr4
- Gm169
- Gp2
- Gpihbp1
- Gpld1
- Hbp1
- Hnt
- Iap
- Izumo1r
- Juno
- Kiaa3001
- Lsamp
- Ly61
- Ly65
- Ly67
- Ly6d
- Ly6e
- Ly6g6c
- Ly6g6d
- Ly6h
- Ly6k
- Lypd1
- Lypd2
- Lypd3
- Lypd4
- Lypd5
- Lypd6b
- Lypd8
- Lypdc1
- Lypdc2
- Mb7
- Mdga1
- Meltf
- Mes
- Mfi2
- Mpf
- Msln
- Mtf
- Negr1
- Ng24
- Ng25
- Ngrl3
- Nrn1
- Nrn1l
- Nt
- Ntm
- Ntra
- Opcml
- Otoa
- Pang
- Pcs
- Plet1
- Prnd
- Prss21
- Prss41
- Psca
- Psg18
- Psg22
- Psg29
- Reck
- Rtn4rl2
- Sca-2
- Spaca4
- Sprn
- Tecta
- Tectb
- Tessp1
- Tex101
- Thb
- Thy-1
- Thy1
- Tsa-1
- Vnn1
- Xpnpep2
|
|
Intra-Golgi traffic
|
|
|
- Akp-3
- Akp3
- Akp5
- Alpg
- Alpi
- Alppl2
- Arf1
- Bet1l
- Cog1
- Cog2
- Cog3
- Cog4
- Cog5
- Cog6
- Cog7
- Cog8
- Cyth1
- Cyth2
- Cyth3
- Cyth4
- Eap
- Gosr1
- Gosr2
- Grp1
- Gs15
- Gs27
- Gs28
- Iap
- Kiaa0258
- Kiaa1134
- Kiaa1432
- Ldlb
- Ldlc
- Napa
- Napb
- Napg
- Nsf
- Pscd1
- Pscd2
- Pscd3
- Pscd4
- Rab30
- Rab33b
- Rab36
- Rab39
- Rab39a
- Rgp1
- Ric1
- Rsb30
- Sec7b
- Skd2
- Snap29
- Snapa
- Snapb
- Snapg
- Stx16
- Stx5
- Stx5a
- Stx6
- Trip11
- Vps45
- Vps45a
- Vti1
- Vti1a
- Vti1l2
- Ykt6
|
|
Formation of xylulose-5-phosphate
|
|
|
- Akr1a1
- Akr1a4
- Cry
- Cryl1
- Dcxr
- Sdh1
- Sord
- Xylb
|
|
Glutathione conjugation
|
|
|
- Akr1a1
- Akr1a4
- Es10
- Esd
- Fsc2
- Gm10639
- Gst2
- Gsta
- Gsta1
- Gsta13
- Gsta2
- Gsta3
- Gsta5
- Gstk1
- Gstm1
- Gstm2
- Gstm3
- Gstm4
- Gstm5
- Gstm6
- Gstm7
- Gstm7-7
- Gsto1
- Gsto2
- Gstp1
- Gstp2
- Gstpia
- Gstpib
- Gsts
- Gstt1
- Gstt2
- Gstx
- Gstya
- Gstyc
- Gstz1
- Gtsttl
- Hpgds
- Maai
- Mgst1
- Mgst2
- Mgst3
- Pgds
- Ptgds2
- Sid478
|
|
Pregnenolone biosynthesis
|
|
|
- Akr1b1
- Akr1b3
- Aldor1
- Aldr1
- Alr2
- Bzrap1
- Bzrp
- Cyp11a
- Cyp11a1
- Es64
- Fdx1
- Fdx1l
- Fdx2
- Fdxr
- Kiaa0612
- Mbr
- Mentho
- Mln64
- Rbp1
- Star
- Stard3
- Stard3nl
- Stard4
- Stard6
- Tspo
- Tspoap1
|
|
Fructose biosynthesis
|
|
|
- Akr1b1
- Akr1b3
- Aldor1
- Aldr1
- Alr2
- Sdh1
- Sord
|
|
Estrogen biosynthesis
|
|
|
- Akr1b10
- Akr1b7
- Akr1b8
- Arom
- Avdp
- Cyp19
- Cyp19a1
- Dhrs8
- Edh17b1
- Edh17b2
- Fgfrp
- Hsd17b1
- Hsd17b11
- Hsd17b14
- Hsd17b2
- Pan1b
|
|
Synthesis of bile acids and bile salts via 27-hydroxycholesterol
|
|
|
- Akr1c20
- Akr1c21
- Akr1c6
- Akr1d1
- Bar
- Cyp12
- Cyp27a1
- Cyp7
- Cyp7a1
- Cyp7b1
- Cyp8
- Cyp8b1
- Fxr
- Grip1
- Hsd17b5
- Hsd3b7
- Ncoa1
- Ncoa2
- Nr1h4
- Nr2b1
- Ptgis
- Rip14
- Rxra
- Src1
- Src2
- Tif2
|
|
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
|
|
|
- Akr1c20
- Akr1c21
- Akr1c6
- Cbr
- Cbr1
- Cox-1
- Cox-2
- Cox1
- Cox2
- Cyp12
- Cyp5
- Cyp5a1
- Cyp8
- Cyp8b1
- Gbf1
- Gsts
- Hpgds
- Hsd17b5
- Pgds
- Pges
- Pges2
- Pghs-b
- Ptgds
- Ptgds2
- Ptges
- Ptges2
- Ptges3
- Ptgis
- Ptgs1
- Ptgs2
- Sid3177
- Tbxas1
- Tebp
- Tis10
|
|
AKT phosphorylates targets in the cytosol
|
|
|
- Akt
- Akt1
- Akt1s1
- Akt2
- Akt3
- Casp9
- Cdkn1a
- Cdkn1b
- Chuk
- Cip1
- Ikka
- Mch6
- Mdm2
- Mkrn1
- Pras
- Rac
- Tsc2
- Waf1
|
|
MTOR signalling
|
|
|
- Akt
- Akt1
- Akt1s1
- Frap
- Frap1
- Gbl
- Hbxip
- Lamtor1
- Lamtor2
- Lamtor3
- Lamtor4
- Lamtor5
- Lst8
- Map2k1ip1
- Mapbp
- Mapbpip
- Mapksp1
- Mlst8
- Mtor
- Pras
- Rac
- Ragd
- Raptor
- Rheb
- Robld3
- Rptor
- Rraga
- Rragb
- Rragc
- Rragd
- Slc38a9
- Xip
- Ywhab
|
|
RAB GEFs exchange GTP for GDP on RABs
|
|
|
- Akt
- Akt1
- Akt2
- Akt3
- Als2
- Als2cl
- Ankrd27
- Bet3
- Bsg4
- Bsp4
- Ccz1
- Chm
- Chml
- D9Bwg0185e
- Denn2b
- Dennd1a
- Dennd1b
- Dennd1c
- Dennd2a
- Dennd2b
- Dennd2c
- Dennd2d
- Dennd3
- Dennd4a
- Dennd4b
- Dennd4c
- Dennd5a
- Dennd5b
- Dennd6a
- Dennd6b
- Ep
- Gapex5
- Gapvd1
- Gdi1
- Gdi2
- Gdi3
- Hps
- Hps1
- Hps4
- Kiaa0066
- Kiaa0258
- Kiaa0358
- Kiaa0476
- Kiaa0839
- Kiaa0870
- Kiaa0872
- Kiaa1432
- Kiaa1521
- Kiaa1882
- Kiaa3020
- Le
- Madd
- Mel
- Mon1a
- Mon1b
- Mtmr5
- Nibp
- Rab1
- Rab10
- Rab12
- Rab13
- Rab14
- Rab18
- Rab1A
- Rab1b
- Rab21
- Rab27a
- Rab27b
- Rab31
- Rab32
- Rab35
- Rab38
- Rab39
- Rab39a
- Rab39b
- Rab3a
- Rab3gap
- Rab3gap1
- Rab3gap2
- Rab3il1
- Rab3ip
- Rab5a
- Rab5b
- Rab5c
- Rab6
- Rab6a
- Rab6b
- Rab6ip1
- Rab7
- Rab7a
- Rab7b
- Rab8
- Rab8a
- Rab8b
- Rab9
- Rab9a
- Rab9b
- Rabex5
- Rabgdia
- Rabgef1
- Rabin8
- Rac
- Rep1
- Rep2
- Rgp1
- Ric1
- Rin1
- Rin2
- Rin3
- Rinl
- Sbdn
- Sbf1
- Sbf2
- Sedl
- Sid99
- St5
- Tmem1
- Trappc1
- Trappc10
- Trappc11
- Trappc12
- Trappc13
- Trappc2
- Trappc2l
- Trappc3
- Trappc4
- Trappc5
- Trappc6a
- Trappc6b
- Trappc8
- Trappc9
- Ttc15
- Ulk1
- Varp
- Ywhae
- nnyRab5a
|
|
G beta:gamma signalling through PI3Kgamma
|
|
|
- Akt
- Akt1
- Akt2
- Akt3
- Arha
- Arha2
- Gnb1
- Gnb2
- Gnb3
- Gnb4
- Gnb5
- Gng1
- Gng10
- Gng11
- Gng12
- Gng13
- Gng2
- Gng3
- Gng4
- Gng5
- Gng7
- Gng8
- Gng9
- Gngt1
- Gngt11
- Gngt2
- Gngt3
- Gngt4
- Gngt5
- Gngt7
- Gngt8
- Gngt9
- Pdk1
- Pdpk1
- Pi3kg1
- Pik3cg
- Pik3r5
- Pik3r6
- Rac
- Rhoa
|
|
Regulation of TP53 Activity through Association with Co-factors
|
|
|
- Akt
- Akt1
- Akt2
- Akt3
- Aspp1
- Aspp2
- Banp
- Brn-3
- Brn-3.2
- Brn3
- Brn3a
- Brn3b
- Hca58
- Hzf
- Nkip1
- P53
- P63
- P73
- P73l
- Phf20
- Pou4f1
- Pou4f2
- Ppp1r13b
- Ppp1r13l
- Rac
- Smar1
- Tp53
- Tp53bp2
- Tp63
- Tp73
- Tp73l
- Trp53
- Trp53bp2
- Trp63
- Trp73
- Zfp385a
- Znf385a
|
|
Regulation of TP53 Degradation
|
|
|
- Akt
- Akt1
- Akt2
- Akt3
- Atm
- Ccna
- Ccna1
- Ccna2
- Ccng
- Ccng1
- Cdc2
- Cdc2a
- Cdk1
- Cdk2
- Cdkn1
- Cdkn2
- Chek2
- Chk2
- Cyca
- Cyca2
- Daxx
- Frap
- Frap1
- Gbl
- Hausp
- Hca58
- Kiaa1999
- Lst8
- Mapkap1
- Mdm2
- Mdm4
- Mdmx
- Mip1
- Mlst8
- Mtor
- P53
- Pdk1
- Pdpk1
- Phf20
- Ppp2ca
- Ppp2cb
- Ppp2r1a
- Ppp2r1b
- Ppp2r5c
- Protor1
- Prr5
- Rac
- Rad53
- Rffl
- Rictor
- Rnf34
- Rps27a
- Sgk
- Sgk1
- Sin1
- Tp53
- Trp53
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
- Ubp41
- Usp2
- Usp7
|
|
CTLA4 inhibitory signaling
|
|
|
- Akt
- Akt1
- Akt2
- Akt3
- B7
- Cd152
- Cd80
- Cd86
- Ctla4
- Fyn
- Kiaa4006
- Lck
- Lsk-t
- Lyn
- Ppp2ca
- Ppp2cb
- Ppp2r1a
- Ppp2r1b
- Ppp2r5a
- Ppp2r5b
- Ppp2r5c
- Ppp2r5d
- Ppp2r5e
- Ptpn11
- Rac
- Src
- Yes
- Yes1
|
|