Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB) June 1, 2016
Species Pathogen Adherence Molecule Ligand Name Ligand Feature Target Source Glycan Sequence Binding PubMed ID
"Extracellular polymeric material, acid proteinase, chitin"
Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)
Oligoglycosylceramides
Human buccal epihelial cells (BECs)
Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
PsaA/B (pH-6 antigen)
Glucosylceramide
Monoglycosylceramides
Glc(b1-1)Cer
Not Binding
Membrane-associated lectins (heavy(170-kDa)/light(35-or31-kDa) subunits)
Galactose
Monosaccharides
Gal
Binding
Capsid proteins
Blood group H1 antigen
Oligosaccharides
Fuc(a1-2)Gal(b1-3)GlcNAc
Binding
Unknown
Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)
Oligoglycosylceramides
Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
Capsid protein VP1
Sialylated oligosaccharides
Oligosaccharides
Cell surface
NeuAc(a2-3)Gal(b1-3)GalNAc
Binding
Heat-labile enterotoxin (type II(LT-Iia))
GT1b
Trisialoglycosphingolipids
NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
Binding
Unknown
Asialo-GM2 (Gangliotriosylceramide; GgO3)
Oligoglycosylceramides
GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
Not Binding
Unknown
Heparan sulfate
Glycosaminoglycans
Mammalian cell surface
Binding
Adhesins
Gb4 (Globoside; Globotetraose; P antigen)
Oligoglycosylceramides
Erythrocytes
GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
Displaying entries 1 - 10 of 1840 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01