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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Sjogren's syndrome
Summary
- Synonym
-
- Sicca syndrome
- Sjogren syndrome
- xerodermosteosis
- Definition
- An autoimmune disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva.
- Super Class
- autoimmune disease of exocrine system
External Links
- Disease Ontology
- DOID:12894
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- GARD
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 1588 | CYP19A1 | cytochrome P450 family 19 subfamily A member 1 | |
| 1869 | E2F1 | E2F transcription factor 1 | |
| 2668 | GDNF | glial cell derived neurotrophic factor | |
| 3117 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | |
| 3119 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 | |
| 3123 | HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | |
| 3187 | HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 | |
| 3383 | ICAM1 | intercellular adhesion molecule 1 | |
| 3458 | IFNG | interferon gamma | |
| 3557 | IL1RN | interleukin 1 receptor antagonist |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 12064 | Bdnf | brain derived neurotrophic factor | |
| 12380 | Cast | calpastatin | |
| 12477 | Ctla4 | cytotoxic T-lymphocyte-associated protein 4 | |
| 12774 | Ccr5 | C-C motif chemokine receptor 5 | |
| 12775 | Ccr7 | C-C motif chemokine receptor 7 | |
| 13076 | Cyp1a1 | cytochrome P450, family 1, subfamily a, polypeptide 1 | |
| 14102 | Fas | Fas cell surface death receptor | |
| 14573 | Gdnf | glial cell line derived neurotrophic factor | |
| 14960 | H2-Aa | histocompatibility 2, class II antigen A, alpha | |
| 14961 | H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 25704 | Il2ra | interleukin 2 receptor subunit alpha | |
| 25712 | Ifng | interferon gamma | |
| 59086 | Tgfb1 | transforming growth factor, beta 1 | |
| 60582 | Il1rn | interleukin 1 receptor antagonist | |
| 81687 | Mmp9 | matrix metallopeptidase 9 | |
| 81818 | Vim | vimentin | |
| 83613 | Nefl | neurofilament light chain | |
| 84024 | Pon1 | paraoxonase 1 | |
| 84349 | Cd40lg | CD40 ligand | |
| 116553 | Il13 | interleukin 13 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 171999 | poml-2 | Arylesterase | |
| 178748 | zmp-3 | Matrix metalloproteinase-C | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180351 | W01F3.2 | Uncharacterized protein | |
| 187297 | poml-1 | PON (paraoxonase) and MEC-6 Like | |
| 188252 | lev-9 | Protein lev-9 |
