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Standards Ontologies Notations
Parkinson's disease

Summary
Synonym
  • Parkinson disease
  • paralysis agitans
Definition
A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.
Super Class
synucleinopathy
Disease Ontology
DOID:14330
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
OMIM
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 180 in total
Gene ID Gene Symbol Description Source
2 A2M alpha-2-macroglobulin
25 ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
43 ACHE acetylcholinesterase (Yt blood group)
50 ACO2 aconitase 2
111 ADCY5 adenylate cyclase 5
131 ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
142 PARP1 poly(ADP-ribose) polymerase 1
157 GRK3 G protein-coupled receptor kinase 3
185 AGTR1 angiotensin II receptor type 1
207 AKT1 AKT serine/threonine kinase 1
Displaying entries 51 - 60 of 146 in total
Gene ID Gene Symbol Description Source
16337 Insr insulin receptor
16846 Lep leptin
17762 Mapt microtubule-associated protein tau
18039 Nefl neurofilament, light polypeptide
18053 Ngfr nerve growth factor receptor (TNFR superfamily, member 16)
18174 Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
18195 Nsf N-ethylmaleimide sensitive fusion protein
18216 Ntsr1 neurotensin receptor 1
18294 Ogg1 8-oxoguanine DNA-glycosylase 1
18386 Oprd1 opioid receptor, delta 1
Displaying entries 1 - 10 of 82 in total
Gene ID Gene Symbol Description Source
24153 A2m alpha-2-macroglobulin
24180 Agtr1a angiotensin II receptor, type 1a
24185 Akt1 AKT serine/threonine kinase 1
24225 Bdnf brain-derived neurotrophic factor
24296 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
24318 Drd2 dopamine receptor D2
24335 Epo erythropoietin
24473 Htr1a 5-hydroxytryptamine receptor 1A
24483 Igf2 insulin-like growth factor 2
24596 Ngfr nerve growth factor receptor
Displaying entries 21 - 25 of 25 in total
Gene ID Gene Symbol Description Source
42803 Hmgcr HMG Coenzyme A reductase
42918 nAChRalpha1 nicotinic Acetylcholine Receptor alpha1
42920 nAChRbeta2 nicotinic Acetylcholine Receptor beta2
43565 Axn Axin
3355109 Parp1 Poly-(ADP-ribose) polymerase 1
Displaying all 9 entries
Gene ID Gene Symbol Description Source
114549 ache acetylcholinesterase (Yt blood group)
436629 nus1 NUS1 dehydrodolichyl diphosphate synthase subunit
437021 tspan36 tetraspanin 36
494492 slc17a6a solute carrier family 17 member 6a
560788 parp1 poly (ADP-ribose) polymerase 1
563467 slc17a8 solute carrier family 17 member 8
768121 foxo1a forkhead box O1 a
100004455 epoa erythropoietin a
100149756 slc17a6b solute carrier family 17 member 6b
Displaying all 7 entries
Gene ID Gene Symbol Description Source Organism
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
398763 agtr1.L angiotensin II receptor type 1 L homeolog Xenopus laevis (African clawed frog)
399170 akt1.S AKT serine/threonine kinase 1 S homeolog Xenopus laevis (African clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
108705891 drd5.S dopamine receptor D5 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 26 in total
Gene ID Gene Symbol Description Source
171965 pgk-1 putative phosphoglycerate kinase
172105 unc-38 Acetylcholine receptor subunit alpha-type unc-38
172150 unc-63 Acetylcholine receptor subunit alpha-type unc-63
173574 gba-1 Putative glucosylceramidase 1
174274 ptc-1 Protein patched homolog 1;SSD domain-containing protein
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175076 ace-3 Carboxylic ester hydrolase
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176291 eat-4 Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4
Displaying entries 11 - 19 of 19 in total
Gene ID Gene Symbol Description Source
853313 PBS2 mitogen-activated protein kinase kinase PBS2
853734 RRN3 rDNA-binding RNA polymerase I transcriptional factor
854276 INP53 phosphatidylinositol-3-/phosphoinositide 5-phosphatase INP53
854713 PRK1 serine/threonine protein kinase PRK1
854900 HMG1 hydroxymethylglutaryl-CoA reductase (NADPH) HMG1
854942 OGG1 8-oxoguanine glycosylase OGG1
855552 PSD1 phosphatidylserine decarboxylase 1
855711 ARK1 serine/threonine protein kinase ARK1
855999 SYH1 Syh1p
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Last updated: December 9, 2024