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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
glioblastoma
Summary
- Synonym
-
- GBM
- adult glioblastoma multiforme
- glioblastoma multiforme
- grade IV adult Astrocytic tumor
- primary glioblastoma multiforme
- spongioblastoma multiforme
- Definition
- A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.
- Super Class
- malignant astrocytoma
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 4193 | MDM2 | MDM2 proto-oncogene | |
| 4255 | MGMT | O-6-methylguanine-DNA methyltransferase | |
| 4313 | MMP2 | matrix metallopeptidase 2 | |
| 4318 | MMP9 | matrix metallopeptidase 9 | |
| 4893 | NRAS | NRAS proto-oncogene, GTPase | |
| 5155 | PDGFB | platelet derived growth factor subunit B | |
| 5159 | PDGFRB | platelet derived growth factor receptor beta | |
| 5167 | ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | |
| 5228 | PGF | placental growth factor | |
| 5291 | PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 12258 | Serping1 | serine (or cysteine) peptidase inhibitor, clade G, member 1 | |
| 12654 | Chi3l1 | chitinase 3 like 1 | |
| 12876 | Cpe | carboxypeptidase E | |
| 12945 | Dmbt1 | deleted in malignant brain tumors 1 | |
| 13030 | Ctsb | cathepsin B | |
| 13036 | Ctsh | cathepsin H | |
| 13645 | Egf | epidermal growth factor | |
| 14056 | Ezh2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | |
| 14256 | Flt3l | FMS-like tyrosine kinase 3 ligand | |
| 14726 | Pdpn | podoplanin |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24479 | Idh1 | isocitrate dehydrogenase (NADP(+)) 1 | |
| 24628 | Pdgfb | platelet derived growth factor subunit B | |
| 24629 | Pdgfrb | platelet derived growth factor receptor beta | |
| 24842 | Tp53 | tumor protein p53 | |
| 25313 | Egf | epidermal growth factor | |
| 25425 | Ctsh | cathepsin H | |
| 25589 | Kdr | kinase insert domain receptor | |
| 25669 | Cpe | carboxypeptidase E | |
| 29414 | Akt3 | AKT serine/threonine kinase 3 | |
| 29527 | Ptgs2 | prostaglandin-endoperoxide synthase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850391 | NPP1 | nucleotide diphosphatase/phosphodiesterase NPP1 | |
| 850871 | IDP2 | isocitrate dehydrogenase (NADP(+)) IDP2 | |
| 851493 | IDP1 | isocitrate dehydrogenase (NADP(+)) IDP1 | |
| 851977 | CTS2 | putative chitinase | |
| 853313 | PBS2 | mitogen-activated protein kinase kinase PBS2 | |
| 855723 | IDP3 | isocitrate dehydrogenase (NADP(+)) IDP3 | |
| 856699 | NPP2 | nucleotide diphosphatase/phosphodiesterase NPP2 |
