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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
lung disease
Summary
- Definition
- A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.
- Super Class
- lower respiratory tract disease
External Links
- Disease Ontology
- DOID:850
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 1636 | ACE | angiotensin I converting enzyme | |
| 1672 | DEFB1 | defensin beta 1 | |
| 1909 | EDNRA | endothelin receptor type A | |
| 1956 | EGFR | epidermal growth factor receptor | |
| 1958 | EGR1 | early growth response 1 | |
| 2150 | F2RL1 | F2R like trypsin receptor 1 | |
| 2878 | GPX3 | glutathione peroxidase 3 | |
| 2908 | NR3C1 | nuclear receptor subfamily 3 group C member 1 | |
| 2934 | GSN | gelsolin | |
| 3115 | HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 16183 | Il2 | interleukin 2 | |
| 17395 | Mmp9 | matrix metallopeptidase 9 | |
| 17523 | Mpo | myeloperoxidase | |
| 17829 | Muc1 | mucin 1, transmembrane | |
| 18127 | Nos3 | nitric oxide synthase 3, endothelial cell | |
| 20296 | Ccl2 | C-C motif chemokine ligand 2 | |
| 20388 | Sftpb | surfactant associated protein B | |
| 20390 | Sftpd | surfactant associated protein D | |
| 21367 | Cntn2 | contactin 2 | |
| 21803 | Tgfb1 | transforming growth factor, beta 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 84007 | C3ar1 | complement C3a receptor 1 | |
| 89808 | Cx3cl1 | C-X3-C motif chemokine ligand 1 | |
| 113959 | C5ar1 | complement C5a receptor 1 | |
| 116553 | Il13 | interleukin 13 | |
| 116562 | Il2 | interleukin 2 | |
| 116677 | F2rl1 | F2R like trypsin receptor 1 | |
| 192155 | Sftpb | surfactant protein B | |
| 302668 | Ace2 | angiotensin converting enzyme 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 173828 | rig-6 | Contactin rig-6 | |
| 174462 | let-23 | Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase | |
| 175383 | zmp-2 | Matrix metalloproteinase-B | |
| 178672 | srp-3 | Serpin domain-containing protein | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180351 | W01F3.2 | Uncharacterized protein | |
| 180780 | acn-1 | Inactive angiotensin-converting enzyme-related protein | |
| 180841 | gnrr-4 | G-protein coupled receptors family 1 profile domain-containing protein | |
| 181178 | gpx-5 | Glutathione peroxidase | |
| 181288 | pxn-2 | Peroxidasin homolog pxn-2 |
