acute myeloid leukemia

Summary
Synonym
  • AML - acute Myeloid Leukemia
  • Leukemia, Myelocytic, acute
  • acute myeloblastic leukaemia
  • acute myeloblastic leukemia
  • acute myelogenous leukaemia
  • acute myelogenous leukemia
  • acute myeloid leukaemia
Definition
A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.
Super Class
myeloid leukemia
Disease Ontology
DOID:9119
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 41 - 50 of 77 in total
Gene ID Gene Symbol Description Source
4605 MYBL2 MYB proto-oncogene like 2
4763 NF1 neurofibromin 1
4846 NOS3 nitric oxide synthase 3
4869 NPM1 nucleophosmin 1
4893 NRAS NRAS proto-oncogene, GTPase
4928 NUP98 nucleoporin 98 and 96 precursor
6347 CCL2 C-C motif chemokine ligand 2
6429 SRSF4 serine and arginine rich splicing factor 4
6455 SH3GL1 SH3 domain containing GRB2 like 1, endophilin A2
6648 SOD2 superoxide dismutase 2
Displaying entries 11 - 20 of 57 in total
Gene ID Gene Symbol Description Source
12986 Csf3r colony stimulating factor 3 receptor
13076 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
13433 Dnmt1 DNA methyltransferase 1
13849 Ephx1 epoxide hydrolase 1, microsomal
14056 Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit
14066 F3 coagulation factor III
14087 Fanca Fanconi anemia, complementation group A
14102 Fas Fas cell surface death receptor
14182 Fgfr1 fibroblast growth factor receptor 1
14255 Flt3 FMS-like tyrosine kinase 3
Displaying entries 1 - 10 of 25 in total
Gene ID Gene Symbol Description Source
24296 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
24479 Idh1 isocitrate dehydrogenase (NADP(+)) 1
24493 Il1a interleukin 1 alpha
24600 Nos3 nitric oxide synthase 3
24770 Ccl2 C-C motif chemokine ligand 2
24787 Sod2 superoxide dismutase 2
24842 Tp53 tumor protein p53
25325 Il10 interleukin 10
29302 Itgb3 integrin subunit beta 3
50662 Runx1 RUNX family transcription factor 1
Displaying entries 11 - 15 of 15 in total
Gene ID Gene Symbol Description Source
41166 Calr Calreticulin
41737 trx trithorax
42160 htl heartless
44885 mys myospheroid
46091 Nup214 Nucleoporin 214kD
Displaying all 4 entries
Gene ID Gene Symbol Description Source
30256 kita KIT proto-oncogene, receptor tyrosine kinase a
30682 vegfaa vascular endothelial growth factor Aa
30705 fgfr1a fibroblast growth factor receptor 1a
114424 cdh1 cadherin 1, type 1, E-cadherin (epithelial)
Displaying all 8 entries
Gene ID Gene Symbol Description Source Organism
373579 kit.L KIT proto-oncogene receptor tyrosine kinase L homeolog Xenopus laevis (African clawed frog)
380373 cxcr4.S C-X-C motif chemokine receptor 4 S homeolog Xenopus laevis (African clawed frog)
397782 fgfr1.S fibroblast growth factor receptor 1 S homeolog Xenopus laevis (African clawed frog)
399444 fgfr1.L fibroblast growth factor receptor 1 L homeolog Xenopus laevis (African clawed frog)
548648 fgfr1 fibroblast growth factor receptor 1 Xenopus tropicalis (tropical clawed frog)
100038176 cxcr4 C-X-C motif chemokine receptor 4 Xenopus tropicalis (tropical clawed frog)
100192360 cxcr4.L C-X-C motif chemokine receptor 4 L homeolog Xenopus laevis (African clawed frog)
100337618 cdh1.S cadherin 1, type 1 S homeolog Xenopus laevis (African clawed frog)
Displaying all 10 entries
Gene ID Gene Symbol Description Source
172813 npp-14 Nuclear pore complex protein 14
175182 ver-1 Protein ver-1
175504 pat-3 Integrin beta pat-3
176240 pat-2 Integrin alpha pat-2
180408 mrp-2 Multidrug resistance-associated protein 1
180409 mrp-1 Multidrug resistance-associated protein 1
180628 cht-1 putative endochitinase
181178 gpx-5 Glutathione peroxidase
182513 gpx-3 Glutathione peroxidase 3
186632 ver-4 Tyrosine-protein kinase receptor ver-4
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
850369 ADP1 putative ATP-dependent permease ADP1
850871 IDP2 isocitrate dehydrogenase (NADP(+)) IDP2
851493 IDP1 isocitrate dehydrogenase (NADP(+)) IDP1
851977 CTS2 putative chitinase
852495 PGI1 glucose-6-phosphate isomerase
852788 NUP145 nucleocytoplasmic transporter NUP145
853590 VPS70 putative zinc metalloprotease
854430 TRE2 putative zinc metalloprotease
855723 IDP3 isocitrate dehydrogenase (NADP(+)) IDP3
855927 TRE1 Tre1p
The Human Phenotype Ontology
Displaying all 3 entries
HPO ID HPO Term
HP:0000006 Autosomal dominant inheritance
HP:0001442 Typified by somatic mosaicism
HP:0004808 Acute myeloid leukemia
Displaying 1 entry
Gene ID Gene Symbol Description
3845 KRAS KRAS proto-oncogene, GTPase

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