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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
colorectal cancer
Summary
- Definition
- A large intestine cancer that is located_in the colon and/or located_in the rectum.
- Super Class
- large intestine cancer
External Links
- Disease Ontology
- DOID:9256
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 4288 | MKI67 | marker of proliferation Ki-67 | |
| 4292 | MLH1 | mutL homolog 1 | |
| 4313 | MMP2 | matrix metallopeptidase 2 | |
| 4318 | MMP9 | matrix metallopeptidase 9 | |
| 4436 | MSH2 | mutS homolog 2 | |
| 4615 | MYD88 | MYD88 innate immune signal transduction adaptor | |
| 4780 | NFE2L2 | NFE2 like bZIP transcription factor 2 | |
| 4851 | NOTCH1 | notch receptor 1 | |
| 4853 | NOTCH2 | notch receptor 2 | |
| 4854 | NOTCH3 | notch receptor 3 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 107831 | Adgrb1 | adhesion G protein-coupled receptor B1 | |
| 107932 | Chd4 | chromodomain helicase DNA binding protein 4 | |
| 109880 | Braf | Braf transforming gene | |
| 207742 | Rnf43 | ring finger protein 43 | |
| 214133 | Tet2 | tet methylcytosine dioxygenase 2 | |
| 228994 | Ythdf1 | YTH N6-methyladenosine RNA binding protein 1 | |
| 230145 | Galnt12 | polypeptide N-acetylgalactosaminyltransferase 12 | |
| 234564 | Ces1f | carboxylesterase 1F | |
| 235626 | Setd2 | SET domain containing 2 | |
| 236732 | Rbm10 | RNA binding motif protein 10 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24185 | Akt1 | AKT serine/threonine kinase 1 | |
| 24346 | Ces1c | carboxylesterase 1C | |
| 24409 | Grin2a | glutamate ionotropic receptor NMDA type subunit 2A | |
| 24648 | Serpina1 | serpin family A member 1 | |
| 24842 | Tp53 | tumor protein p53 | |
| 24856 | Ttr | transthyretin | |
| 25058 | Hk1 | hexokinase 1 | |
| 25149 | Esr2 | estrogen receptor 2 | |
| 25233 | Akt2 | AKT serine/threonine kinase 2 | |
| 25273 | Smo | smoothened, frizzled class receptor |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31293 | N | Notch | |
| 31792 | Nrg | Neuroglian | |
| 32556 | Stim | Stromal interaction molecule | |
| 33196 | smo | smoothened | |
| 33496 | lilli | lilliputian | |
| 34091 | Spn28Dc | Serpin 28Dc | |
| 35560 | Bap170 | Brahma associated protein 170kD | |
| 37455 | Egfr | Epidermal growth factor receptor | |
| 39392 | Est-6 | Esterase 6 | |
| 39393 | Est-P | Esterase P |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30225 | smo | smoothened, frizzled class receptor | |
| 30682 | vegfaa | vascular endothelial growth factor Aa | |
| 30718 | notch1a | notch receptor 1a | |
| 406411 | rhoaa | ras homolog gene family, member Aa | |
| 406659 | rhoac | ras homolog gene family, member Ac | |
| 554230 | kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) | |
| 559736 | galnt12 | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 | |
| 100006041 | rhoab | ras homolog gene family, member Ab |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 373801 | tgfb2.L | transforming growth factor beta 2 L homeolog | Xenopus laevis (African clawed frog) | |
| 379783 | akt2.L | v-akt murine thymoma viral oncogene homolog 2 L homeolog | Xenopus laevis (African clawed frog) | |
| 380373 | cxcr4.S | C-X-C motif chemokine receptor 4 S homeolog | Xenopus laevis (African clawed frog) | |
| 397778 | tgfb1.L | transforming growth factor beta 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 397787 | ttr.L | transthyretin L homeolog | Xenopus laevis (African clawed frog) | |
| 399170 | akt1.S | AKT serine/threonine kinase 1 S homeolog | Xenopus laevis (African clawed frog) | |
| 399187 | adam10.S | ADAM metallopeptidase domain 10 S homeolog | Xenopus laevis (African clawed frog) | |
| 399347 | fgfr3.S | fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog | Xenopus laevis (African clawed frog) | |
| 432172 | akt2.S | v-akt murine thymoma viral oncogene homolog 2 S homeolog | Xenopus laevis (African clawed frog) | |
| 100037842 | notch1 | notch 1 receptor | Xenopus tropicalis (tropical clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 180622 | ddr-2 | Discoidin domain-containing receptor tyrosine kinase B | |
| 180638 | wrt-6 | Warthog protein 6 N-product | |
| 181178 | gpx-5 | Glutathione peroxidase | |
| 181489 | adm-2 | Disintegrin and metalloproteinase domain-containing protein adm-2 | |
| 181723 | hda-4 | Histone deacetylase 4 | |
| 182513 | gpx-3 | Glutathione peroxidase 3 | |
| 186632 | ver-4 | Tyrosine-protein kinase receptor ver-4 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850438 | ERS1 | cystinosin-like protein ERS1 | |
| 850614 | HXK1 | hexokinase 1 | |
| 851543 | OSH2 | oxysterol-binding protein related protein OSH2 | |
| 851670 | GIS1 | histone demethylase GIS1 | |
| 852410 | CYC8 | transcription regulator CYC8 | |
| 852546 | GPX2 | glutathione peroxidase GPX2 | |
| 853313 | PBS2 | mitogen-activated protein kinase kinase PBS2 | |
| 853361 | ALY2 | Aly2p | |
| 853770 | BUD2 | GTPase-activating protein BUD2 | |
| 853842 | GPX1 | glutathione peroxidase GPX1 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000006 | Autosomal dominant inheritance |
| HP:0006716 | Hereditary nonpolyposis colorectal carcinoma |
| HP:0002891 | Uterine leiomyosarcoma |
| HP:0006753 | Neoplasm of the stomach |
| HP:0001442 | Typified by somatic mosaicism |
| HP:0006740 | Transitional cell carcinoma of the bladder |
| HP:0005584 | Renal cell carcinoma |
