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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
colorectal cancer
Summary
- Definition
- A large intestine cancer that is located_in the colon and/or located_in the rectum.
- Super Class
- large intestine cancer
External Links
- Disease Ontology
- DOID:9256
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 2194 | FASN | fatty acid synthase | |
| 2195 | FAT1 | FAT atypical cadherin 1 | |
| 2261 | FGFR3 | fibroblast growth factor receptor 3 | |
| 2268 | FGR | FGR proto-oncogene, Src family tyrosine kinase | |
| 2355 | FOSL2 | FOS like 2, AP-1 transcription factor subunit | |
| 2571 | GAD1 | glutamate decarboxylase 1 | |
| 2729 | GCLC | glutamate-cysteine ligase catalytic subunit | |
| 2735 | GLI1 | GLI family zinc finger 1 | |
| 2876 | GPX1 | glutathione peroxidase 1 | |
| 2877 | GPX2 | glutathione peroxidase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 18129 | Notch2 | notch 2 | |
| 18131 | Notch3 | notch 3 | |
| 18213 | Ntrk3 | neurotrophic tyrosine kinase, receptor, type 3 | |
| 18214 | Ddr2 | discoidin domain receptor family, member 2 | |
| 18706 | Pik3ca | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | |
| 18708 | Pik3r1 | phosphoinositide-3-kinase regulatory subunit 1 | |
| 19248 | Ptpn12 | protein tyrosine phosphatase, non-receptor type 12 | |
| 19249 | Ptpn13 | protein tyrosine phosphatase, non-receptor type 13 | |
| 19271 | Ptprj | protein tyrosine phosphatase receptor type J | |
| 19281 | Ptprt | protein tyrosine phosphatase receptor type T |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24185 | Akt1 | AKT serine/threonine kinase 1 | |
| 24346 | Ces1c | carboxylesterase 1C | |
| 24409 | Grin2a | glutamate ionotropic receptor NMDA type subunit 2A | |
| 24648 | Serpina1 | serpin family A member 1 | |
| 24842 | Tp53 | tumor protein p53 | |
| 24856 | Ttr | transthyretin | |
| 25058 | Hk1 | hexokinase 1 | |
| 25149 | Esr2 | estrogen receptor 2 | |
| 25233 | Akt2 | AKT serine/threonine kinase 2 | |
| 25273 | Smo | smoothened, frizzled class receptor |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31293 | N | Notch | |
| 31792 | Nrg | Neuroglian | |
| 32556 | Stim | Stromal interaction molecule | |
| 33196 | smo | smoothened | |
| 33496 | lilli | lilliputian | |
| 34091 | Spn28Dc | Serpin 28Dc | |
| 35560 | Bap170 | Brahma associated protein 170kD | |
| 37455 | Egfr | Epidermal growth factor receptor | |
| 39392 | Est-6 | Esterase 6 | |
| 39393 | Est-P | Esterase P |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30225 | smo | smoothened, frizzled class receptor | |
| 30682 | vegfaa | vascular endothelial growth factor Aa | |
| 30718 | notch1a | notch receptor 1a | |
| 406411 | rhoaa | ras homolog gene family, member Aa | |
| 406659 | rhoac | ras homolog gene family, member Ac | |
| 554230 | kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) | |
| 559736 | galnt12 | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 | |
| 100006041 | rhoab | ras homolog gene family, member Ab |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 373801 | tgfb2.L | transforming growth factor beta 2 L homeolog | Xenopus laevis (African clawed frog) | |
| 379783 | akt2.L | v-akt murine thymoma viral oncogene homolog 2 L homeolog | Xenopus laevis (African clawed frog) | |
| 380373 | cxcr4.S | C-X-C motif chemokine receptor 4 S homeolog | Xenopus laevis (African clawed frog) | |
| 397778 | tgfb1.L | transforming growth factor beta 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 397787 | ttr.L | transthyretin L homeolog | Xenopus laevis (African clawed frog) | |
| 399170 | akt1.S | AKT serine/threonine kinase 1 S homeolog | Xenopus laevis (African clawed frog) | |
| 399187 | adam10.S | ADAM metallopeptidase domain 10 S homeolog | Xenopus laevis (African clawed frog) | |
| 399347 | fgfr3.S | fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog | Xenopus laevis (African clawed frog) | |
| 432172 | akt2.S | v-akt murine thymoma viral oncogene homolog 2 S homeolog | Xenopus laevis (African clawed frog) | |
| 100037842 | notch1 | notch 1 receptor | Xenopus tropicalis (tropical clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 172233 | unc-40 | Netrin receptor unc-40 | |
| 172689 | sup-17 | Disintegrin and metalloproteinase domain-containing protein 10 homolog | |
| 174044 | sma-6 | Serine/threonine-protein kinase receptor sma-6 | |
| 174462 | let-23 | Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase | |
| 175182 | ver-1 | Protein ver-1 | |
| 175201 | stim-1 | Stromal interaction molecule 1 | |
| 175590 | cdh-4 | Cadherin-4 | |
| 176282 | lin-12 | lin-12/Notch intracellular domain | |
| 176286 | glp-1 | glp-1/Notch intracellular domain | |
| 176575 | plr-1 | putative E3 ubiquitin-protein ligase plr-1 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000006 | Autosomal dominant inheritance |
| HP:0006716 | Hereditary nonpolyposis colorectal carcinoma |
| HP:0002891 | Uterine leiomyosarcoma |
| HP:0006753 | Neoplasm of the stomach |
| HP:0001442 | Typified by somatic mosaicism |
| HP:0006740 | Transitional cell carcinoma of the bladder |
| HP:0005584 | Renal cell carcinoma |
