diabetes mellitus

Summary
Synonym
  • diabetes
Definition
A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.
Super Class
glucose metabolism disease
Disease Ontology
DOID:9351
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 11 - 20 of 24 in total
Gene ID Gene Symbol Description Source
3077 HFE homeostatic iron regulator
3156 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
3569 IL6 interleukin 6
3630 INS insulin
3643 INSR insulin receptor
3673 ITGA2 integrin subunit alpha 2
3767 KCNJ11 potassium inwardly rectifying channel subfamily J member 11
5789 PTPRD protein tyrosine phosphatase receptor type D
6649 SOD3 superoxide dismutase 3
7099 TLR4 toll like receptor 4
Displaying all 2 entries
Gene ID Gene Symbol Description Source
12753 Clock clock circadian regulator
19013 Ppara peroxisome proliferator activated receptor alpha
Displaying all 4 entries
Gene ID Gene Symbol Description Source
24617 Serpine1 serpin family E member 1
25704 Il2ra interleukin 2 receptor subunit alpha
260320 F7 coagulation factor VII
299858 Lrp1 LDL receptor related protein 1
Displaying all 2 entries
Gene ID Gene Symbol Description Source
37778 gbb glass bottom boat
42549 InR Insulin-like receptor
Displaying 1 entry
Gene ID Gene Symbol Description Source
559080 cftr CF transmembrane conductance regulator
Displaying all 3 entries
Gene ID Gene Symbol Description Source
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176000 ogt-1 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase;protein O-GlcNAc transferase
Related Glycoprotein
Displaying 1 entry
UniProt ID Protein Name Source
O08785 Circadian locomoter output cycles protein kaput

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Last updated: April 7, 2025