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Standards Ontologies Notations
Guidelines
MIRAGE
type 2 diabetes mellitus

Summary
Synonym
  • NIDDM
  • insulin resistance
  • non-insulin-dependent diabetes mellitus
  • type 2 diabetes
  • type II diabetes mellitus
Definition
A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Super Class
diabetes mellitus
Disease Ontology
DOID:9352
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 129 in total
Gene ID Gene Symbol Description Source
19 ABCA1 ATP binding cassette subfamily A member 1
150 ADRA2A adrenoceptor alpha 2A
155 ADRB3 adrenoceptor beta 3
177 AGER advanced glycosylation end-product specific receptor
197 AHSG alpha 2-HS glycoprotein
208 AKT2 AKT serine/threonine kinase 2
217 ALDH2 aldehyde dehydrogenase 2 family member
229 ALDOB aldolase, fructose-bisphosphate B
231 AKR1B1 aldo-keto reductase family 1 member B
338 APOB apolipoprotein B
Displaying entries 11 - 19 of 19 in total
Gene ID Gene Symbol Description Source
20614 Snap25 synaptosomal-associated protein 25
50518 a nonagouti
53412 Ppp1r3c protein phosphatase 1, regulatory subunit 3C
68916 Cdkal1 CDK5 regulatory subunit associated protein 1-like 1
103988 Gck glucokinase
140491 Ppp1r3a protein phosphatase 1, regulatory subunit 3A
228355 Madd MAP-kinase activating death domain
266690 Cyb5r4 cytochrome b5 reductase 4
384783 Irs2 insulin receptor substrate 2
Displaying all 2 entries
Gene ID Gene Symbol Description Source
33496 lilli lilliputian
42549 InR Insulin-like receptor
Displaying all 3 entries
Gene ID Gene Symbol Description Source
176000 ogt-1 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase;protein O-GlcNAc transferase
177850 gon-1 A disintegrin and metalloproteinase with thrombospondin motifs gon-1;Peptidase M12B domain-containing protein
266823 parp-1 Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
856386 LAG1 sphingosine N-acyltransferase LAG1
Related Glycoprotein
Displaying 1 entry
UniProt ID Protein Name Source
P38703 Ceramide synthase LAG1
The Human Phenotype Ontology
Displaying all 4 entries
HPO ID HPO Term
HP:0000855 Insulin resistance
HP:0005978 Type II diabetes mellitus
HP:0000006 Autosomal dominant inheritance
HP:0003584 Late onset
Displaying all 6 entries
Gene ID Gene Symbol Description
3990 LIPC lipase C, hepatic type
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
2645 GCK glucokinase
5506 PPP1R3A protein phosphatase 1 regulatory subunit 3A
6514 SLC2A2 solute carrier family 2 member 2
2820 GPD2 glycerol-3-phosphate dehydrogenase 2
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: March 31, 2025