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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
obesity
Summary
- Definition
- An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
- Super Class
- overnutrition
External Links
- Disease Ontology
- DOID:9970
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- MGI genotype (from TogoID)
-
- 3766125
- 3821619
- 3821616
- 3817475
- 3799316
- 3784993
- 3784991
- 3773447
- 3772367
- 3822317
- 3766122
- 3721145
- 3715252
- 3694548
- 3689720
- 3664551
- 3664276
- 3655835
- 5515728
- 7545554
- 7545550
- 7545546
- 6273993
- 5828524
- 5766495
- 5763310
- 5763241
- 3655832
- 5447549
- 5300906
- 3850836
- 3847120
- 3840234
- 3832410
- 3822318
- 3033164
- 3511746
- 3055585
- 3055584
- 3053798
- 3041643
- 3036853
- 3036852
- 3033165
- 3511747
- 2681522
- 2680503
- 2669229
- 2663736
- 2654708
- 2653295
- 2651886
- 2388265
- 3589409
- 3655811
- 3639781
- 3639355
- 3639354
- 3629805
- 3623749
- 3620067
- 3611807
- 2174793
- 3586756
- 3582615
- 3580003
- 3579026
- 3577766
- 3526863
- 3511748
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 19 | ABCA1 | ATP binding cassette subfamily A member 1 | |
| 32 | ACACB | acetyl-CoA carboxylase beta | |
| 38 | ACAT1 | acetyl-CoA acetyltransferase 1 | |
| 51 | ACOX1 | acyl-CoA oxidase 1 | |
| 123 | PLIN2 | perilipin 2 | |
| 133 | ADM | adrenomedullin | |
| 134 | ADORA1 | adenosine A1 receptor | |
| 154 | ADRB2 | adrenoceptor beta 2 | |
| 155 | ADRB3 | adrenoceptor beta 3 | |
| 177 | AGER | advanced glycosylation end-product specific receptor |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 235611 | Plxnb1 | plexin B1 | |
| 236266 | Alms1 | ALMS1, centrosome and basal body associated | |
| 237979 | Sdk2 | sidekick cell adhesion molecule 2 | |
| 238055 | Apob | apolipoprotein B | |
| 239102 | Zfhx2 | zinc finger homeobox 2 | |
| 239857 | Cadm2 | cell adhesion molecule 2 | |
| 240913 | Adamts4 | ADAM metallopeptidase with thrombospondin type 1 motif 4 | |
| 329628 | Fat4 | FAT atypical cadherin 4 | |
| 330222 | Sdk1 | sidekick cell adhesion molecule 1 | |
| 330260 | Pon2 | paraoxonase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 25601 | Oprm1 | opioid receptor, mu 1 | |
| 25608 | Lep | leptin | |
| 25625 | Tnfrsf1a | TNF receptor superfamily member 1A | |
| 25635 | Mc4r | melanocortin 4 receptor | |
| 25644 | Bmp6 | bone morphogenetic protein 6 | |
| 25645 | Adrb3 | adrenoceptor beta 3 | |
| 25651 | Selp | selectin P | |
| 25664 | Pparg | peroxisome proliferator-activated receptor gamma | |
| 25669 | Cpe | carboxypeptidase E | |
| 25670 | Il15 | interleukin 15 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31002 | Appl | beta amyloid protein precursor-like | |
| 31017 | sdk | sidekick | |
| 31234 | Pdfr | Pigment-dispersing factor receptor | |
| 31293 | N | Notch | |
| 32545 | Gapdh2 | Glyceraldehyde 3 phosphate dehydrogenase 2 | |
| 32556 | Stim | Stromal interaction molecule | |
| 32974 | Zw | Zwischenferment | |
| 33007 | Dop2R | Dopamine 2-like receptor | |
| 33245 | ds | dachsous | |
| 33627 | ft | fat |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30128 | wnt1 | wingless-type MMTV integration site family, member 1 | |
| 30308 | wnt10b | wingless-type MMTV integration site family, member 10b | |
| 30686 | myca | MYC proto-oncogene, bHLH transcription factor a | |
| 30705 | fgfr1a | fibroblast growth factor receptor 1a | |
| 30718 | notch1a | notch receptor 1a | |
| 266751 | adra2b | adrenoceptor alpha 2B | |
| 286833 | mc4r | melanocortin 4 receptor | |
| 317743 | gapdh | glyceraldehyde-3-phosphate dehydrogenase | |
| 393141 | mycb | MYC proto-oncogene, bHLH transcription factor b | |
| 406207 | mttp | microsomal triglyceride transfer protein |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 373580 | crhr1.2.S | corticotropin releasing hormone receptor 1, gene 2 S homeolog | Xenopus laevis (African clawed frog) | |
| 373759 | cnr1.S | cannabinoid receptor 1 (brain) S homeolog | Xenopus laevis (African clawed frog) | |
| 373802 | pomc.S | proopiomelanocortin S homeolog | Xenopus laevis (African clawed frog) | |
| 378584 | drd2.L | dopamine receptor D2 L homeolog | Xenopus laevis (African clawed frog) | |
| 378693 | npy2r.S | neuropeptide Y receptor Y2 S homeolog | Xenopus laevis (African clawed frog) | |
| 379783 | akt2.L | v-akt murine thymoma viral oncogene homolog 2 L homeolog | Xenopus laevis (African clawed frog) | |
| 380532 | pomc.L | proopiomelanocortin L homeolog | Xenopus laevis (African clawed frog) | |
| 394945 | cfd | complement factor D | Xenopus tropicalis (tropical clawed frog) | |
| 397778 | tgfb1.L | transforming growth factor beta 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 397782 | fgfr1.S | fibroblast growth factor receptor 1 S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 177940 | egl-21 | Carboxypeptidase E | |
| 178046 | gspd-1 | Glucose-6-phosphate 1-dehydrogenase | |
| 178126 | nhx-9 | putative Na(+)/H(+) antiporter nhx-9 | |
| 179197 | cri-2 | Putative metalloproteinase inhibitor tag-225 | |
| 179347 | dop-2 | Dopamine receptor 2 | |
| 179663 | enpp-1 | Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.1;NUC domain-containing protein | |
| 179665 | C27A7.3 | Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.1;Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.3 | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180251 | asp-1 | Aspartic protease 1 | |
| 180351 | W01F3.2 | Uncharacterized protein |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850317 | GLK1 | glucokinase | |
| 850391 | NPP1 | nucleotide diphosphatase/phosphodiesterase NPP1 | |
| 850442 | SRB8 | Srb8p | |
| 850614 | HXK1 | hexokinase 1 | |
| 850647 | PUF3 | mRNA-binding protein PUF3 | |
| 851241 | CNE1 | calnexin | |
| 851888 | DPL1 | sphinganine-1-phosphate aldolase DPL1 | |
| 851974 | YPR1 | trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1 | |
| 852053 | SSN2 | Ssn2p | |
| 852102 | IZH1 | PAQR-type receptor |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0010982 | Polygenic inheritance |
| HP:0000006 | Autosomal dominant inheritance |
| HP:0012340 | Decreased resting energy expenditure |
| HP:0001513 | Obesity |
