obesity

Summary
Definition
An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Super Class
overnutrition
Related Genes
Displaying entries 1 - 10 of 343 in total
Gene ID Gene Symbol Description Source
19 ABCA1 ATP binding cassette subfamily A member 1
32 ACACB acetyl-CoA carboxylase beta
38 ACAT1 acetyl-CoA acetyltransferase 1
51 ACOX1 acyl-CoA oxidase 1
123 PLIN2 perilipin 2
133 ADM adrenomedullin
134 ADORA1 adenosine A1 receptor
154 ADRB2 adrenoceptor beta 2
155 ADRB3 adrenoceptor beta 3
177 AGER advanced glycosylation end-product specific receptor
Displaying entries 1 - 10 of 241 in total
Gene ID Gene Symbol Description Source
11303 Abca1 ATP-binding cassette, sub-family A member 1
11421 Ace angiotensin I converting enzyme
11450 Adipoq adiponectin, C1Q and collagen domain containing
11520 Plin2 perilipin 2
11537 Cfd complement factor D
11539 Adora1 adenosine A1 receptor
11555 Adrb2 adrenergic receptor, beta 2
11556 Adrb3 adrenergic receptor, beta 3
11596 Ager advanced glycosylation end product-specific receptor
11625 Ahsg alpha-2-HS-glycoprotein
Displaying entries 131 - 140 of 151 in total
Gene ID Gene Symbol Description Source
155192 Abcg8 ATP binding cassette subfamily G member 8
170496 Lcn2 lipocalin 2
170538 Prkcd protein kinase C, delta
171374 Atp5f1b ATP synthase F1 subunit beta
192155 Sftpb surfactant protein B
245965 Atp5f1d ATP synthase F1 subunit delta
246075 Prlhr prolactin releasing hormone receptor
260320 F7 coagulation factor VII
287561 Ccl7 C-C motif chemokine ligand 7
291437 Lipg lipase G, endothelial type
Displaying entries 1 - 10 of 43 in total
Gene ID Gene Symbol Description Source
31002 Appl beta amyloid protein precursor-like
31017 sdk sidekick
31234 Pdfr Pigment-dispersing factor receptor
31293 N Notch
32545 Gapdh2 Glyceraldehyde 3 phosphate dehydrogenase 2
32556 Stim Stromal interaction molecule
32974 Zw Zwischenferment
33007 Dop2R Dopamine 2-like receptor
33245 ds dachsous
33627 ft fat
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
30128 wnt1 wingless-type MMTV integration site family, member 1
30308 wnt10b wingless-type MMTV integration site family, member 10b
30686 myca MYC proto-oncogene, bHLH transcription factor a
30705 fgfr1a fibroblast growth factor receptor 1a
30718 notch1a notch receptor 1a
266751 adra2b adrenoceptor alpha 2B
286833 mc4r melanocortin 4 receptor
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
393141 mycb MYC proto-oncogene, bHLH transcription factor b
406207 mttp microsomal triglyceride transfer protein
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source Organism
373580 crhr1.2.S corticotropin releasing hormone receptor 1, gene 2 S homeolog Xenopus laevis (African clawed frog)
373759 cnr1.S cannabinoid receptor 1 (brain) S homeolog Xenopus laevis (African clawed frog)
373802 pomc.S proopiomelanocortin S homeolog Xenopus laevis (African clawed frog)
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
378693 npy2r.S neuropeptide Y receptor Y2 S homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380532 pomc.L proopiomelanocortin L homeolog Xenopus laevis (African clawed frog)
394945 cfd complement factor D Xenopus tropicalis (tropical clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
397782 fgfr1.S fibroblast growth factor receptor 1 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 21 - 30 of 51 in total
Gene ID Gene Symbol Description Source
177940 egl-21 Carboxypeptidase E
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
178126 nhx-9 putative Na(+)/H(+) antiporter nhx-9
179197 cri-2 Putative metalloproteinase inhibitor tag-225
179347 dop-2 Dopamine receptor 2
179663 enpp-1 Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.1;NUC domain-containing protein
179665 C27A7.3 Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.1;Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.3
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180251 asp-1 Aspartic protease 1
180351 W01F3.2 Uncharacterized protein
Displaying entries 11 - 20 of 29 in total
Gene ID Gene Symbol Description Source
852128 EMI2 putative glucokinase
852276 SLA1 cytoskeletal protein-binding protein SLA1
852543 VVS1 Vvs1p
852639 HXK2 hexokinase 2
852667 POX1 acyl-CoA oxidase
853106 TDH3 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3
853395 TDH1 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1
853465 TDH2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2
854080 YOL075C uncharacterized protein
854287 GCY1 glycerol 2-dehydrogenase (NADP(+)) GCY1
The Human Phenotype Ontology
Displaying all 5 entries
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0010982 Polygenic inheritance
HP:0000006 Autosomal dominant inheritance
HP:0012340 Decreased resting energy expenditure
HP:0001513 Obesity
Displaying all 2 entries
Gene ID Gene Symbol Description
9672 SDC3 syndecan 3
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1

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Last updated: December 9, 2024