obesity

Summary
Definition
An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Super Class
overnutrition
Disease Ontology
DOID:9970
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
Related Genes
Displaying entries 111 - 120 of 343 in total
Gene ID Gene Symbol Description Source
3091 HIF1A hypoxia inducible factor 1 subunit alpha
3098 HK1 hexokinase 1
3099 HK2 hexokinase 2
3157 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1
3240 HP haptoglobin
3250 HPR haptoglobin-related protein
3290 HSD11B1 hydroxysteroid 11-beta dehydrogenase 1
3291 HSD11B2 hydroxysteroid 11-beta dehydrogenase 2
3293 HSD17B3 hydroxysteroid 17-beta dehydrogenase 3
3295 HSD17B4 hydroxysteroid 17-beta dehydrogenase 4
Displaying entries 171 - 180 of 241 in total
Gene ID Gene Symbol Description Source
21939 Cd40 CD40 antigen
21947 Cd40lg CD40 ligand
22041 Trf transferrin
22157 Tulp1 TUB like protein 1
22228 Ucp2 uncoupling protein 2 (mitochondrial, proton carrier)
22371 Vwf Von Willebrand factor
22408 Wnt1 wingless-type MMTV integration site family, member 1
22410 Wnt10b wingless-type MMTV integration site family, member 10B
26383 Fto FTO alpha-ketoglutarate dependent dioxygenase
27409 Abcg5 ATP binding cassette subfamily G member 5
Displaying entries 121 - 130 of 151 in total
Gene ID Gene Symbol Description Source
85496 Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1
94203 Pgf placental growth factor
113936 Cpb2 carboxypeptidase B2
113959 C5ar1 complement C5a receptor 1
113965 Hadh hydroxyacyl-CoA dehydrogenase
114628 Abcg5 ATP binding cassette subfamily G member 5
116510 Timp1 TIMP metallopeptidase inhibitor 1
116550 Atp5f1c ATP synthase F1 subunit gamma
116673 Sdc3 syndecan 3
117261 Slc15a1 solute carrier family 15 member 1
Displaying entries 1 - 10 of 43 in total
Gene ID Gene Symbol Description Source
31002 Appl beta amyloid protein precursor-like
31017 sdk sidekick
31234 Pdfr Pigment-dispersing factor receptor
31293 N Notch
32545 Gapdh2 Glyceraldehyde 3 phosphate dehydrogenase 2
32556 Stim Stromal interaction molecule
32974 Zw Zwischenferment
33007 Dop2R Dopamine 2-like receptor
33245 ds dachsous
33627 ft fat
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
30128 wnt1 wingless-type MMTV integration site family, member 1
30308 wnt10b wingless-type MMTV integration site family, member 10b
30686 myca MYC proto-oncogene, bHLH transcription factor a
30705 fgfr1a fibroblast growth factor receptor 1a
30718 notch1a notch receptor 1a
266751 adra2b adrenoceptor alpha 2B
286833 mc4r melanocortin 4 receptor
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
393141 mycb MYC proto-oncogene, bHLH transcription factor b
406207 mttp microsomal triglyceride transfer protein
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source Organism
373580 crhr1.2.S corticotropin releasing hormone receptor 1, gene 2 S homeolog Xenopus laevis (African clawed frog)
373759 cnr1.S cannabinoid receptor 1 (brain) S homeolog Xenopus laevis (African clawed frog)
373802 pomc.S proopiomelanocortin S homeolog Xenopus laevis (African clawed frog)
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
378693 npy2r.S neuropeptide Y receptor Y2 S homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380532 pomc.L proopiomelanocortin L homeolog Xenopus laevis (African clawed frog)
394945 cfd complement factor D Xenopus tropicalis (tropical clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
397782 fgfr1.S fibroblast growth factor receptor 1 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 51 in total
Gene ID Gene Symbol Description Source
171782 abt-2 ABC transporter domain-containing protein
171994 lin-44 Abnormal cell lineage protein 44
171999 poml-2 Arylesterase
173169 eif-6 Eukaryotic translation initiation factor 6
173399 cwn-1 Protein Wnt-1
174578 gpd-4 Glyceraldehyde-3-phosphate dehydrogenase 4
174603 gpd-1 Glyceraldehyde-3-phosphate dehydrogenase 1
174685 ptp-3 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase
175201 stim-1 Stromal interaction molecule 1
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
Displaying entries 1 - 10 of 29 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850442 SRB8 Srb8p
850614 HXK1 hexokinase 1
850647 PUF3 mRNA-binding protein PUF3
851241 CNE1 calnexin
851888 DPL1 sphinganine-1-phosphate aldolase DPL1
851974 YPR1 trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1
852053 SSN2 Ssn2p
852102 IZH1 PAQR-type receptor
The Human Phenotype Ontology
Displaying all 5 entries
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0010982 Polygenic inheritance
HP:0000006 Autosomal dominant inheritance
HP:0012340 Decreased resting energy expenditure
HP:0001513 Obesity
Displaying all 2 entries
Gene ID Gene Symbol Description
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
9672 SDC3 syndecan 3

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Last updated: December 9, 2024