GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **251 - 275** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲
Processing of DNA double-strand break ends	ATR-interacting protein BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Checkpoint protein HUS1 Claspin Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 DNA endonuclease RBBP8 DNA repair protein RAD50 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase HERC2 E3 ubiquitin-protein ligase RNF168 E3 ubiquitin-protein ligase RNF4 E3 ubiquitin-protein ligase RNF8 Exonuclease 1 Fanconi anemia group J protein Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H4 Histone acetyltransferase KAT5 Histone-lysine N-methyltransferase NSD2 Lys-63-specific deubiquitinase BRCC36 Mediator of DNA damage checkpoint protein 1 NAD-dependent protein deacylase sirtuin-6 Nibrin Polyubiquitin-B Polyubiquitin-C Protein timeless homolog RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit SUMO-conjugating enzyme UBC9 Serine-protein kinase ATM Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1 Serine/threonine-protein phosphatase 4 catalytic subunit Serine/threonine-protein phosphatase 4 regulatory subunit 2 Small ubiquitin-related modifier 2 TIMELESS-interacting protein TP53-binding protein 1 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14757 O60671 O60814 O60921 O60934 O75943 O76064 O95714 O96028 P06899 P0CG47 P0CG48 P15927 P16104 P20248 P23527 P24941 P27694 P33778 P35244 P35249 P35250 P38398 P40937 P40938 P46736 P49959 P51530 P54132 P57053 P58876 P60510 P61088 P61956 P62805 P62807 P62979 P62987 P63279 P78317 P78396 Q12888 Q13315 Q13472 Q13535 Q14191 Q14676 Q15819 Q16695 Q16778 Q6UWZ7 Q6WBX8 Q8IYW5 Q8N257 Q8N2W9 Q8N6T7 Q8WXE1 Q92547 Q92878 Q92993 Q93079 Q96A08 Q96E14 Q96RL1 Q99638 Q99708 Q99728 Q99877 Q99879 Q99880 Q9BSD3 Q9BVW5 Q9BX63 Q9H9A7 Q9HAW4 Q9NWV8 Q9NXR7 Q9NY27 Q9UNS1 Q9UQ84	ABRA1 ABRAXAS1 AGS1 ATM ATR ATRIP BABAM1 BABAM2 BACH1 BARD1 BLM BLU BRCA1 BRCC3 BRCC36 BRCC45 BRE BRIP1 C12orf32 C16orf75 C19orf62 C6.1A C9orf76 CCDC98 CCN1 CCNA CCNA1 CCNA2 CDK2 CDKN2 CHEK1 CHK1 CLSPN CTIP CXorf53 DNA2 DNA2L EXO1 EXOI FAM175A FANCJ FRP1 H2AFX H2AX H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-4 H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HERC2 HEX1 HIRIP1 HIRIP2 HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 HNGS1 HTATIP HUS1 KAT5 KIAA0083 KIAA0170 KIAA0259 KIAA0646 KIAA1090 MDC1 MERIT40 MMS2 MMSET MRE11 MRE11A NBA1 NBN NBS NBS1 NFBD1 NSD2 P95 PIAS4 PIASG PPP4 PPP4C PPP4R2 PPX R24L RAD1 RAD17 RAD50 RAD9A RAD9B RAP80 RBBP8 REC1 RECQ2 RECQ3 RECQL2 RECQL3 REPA1 REPA2 REPA3 RFC2 RFC3 RFC4 RFC5 RHINO RHNO1 RMI1 RMI2 RNF168 RNF4 RNF53 RNF8 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A RXRIP110 SIR2L6 SIRT6 SMT3B SMT3H2 SNURF SUMO2 TIM TIM1 TIMELESS TIMELESS1 TIP60 TIPIN TOP3 TOP3A TOPBP1 TP53BP1 TRX5 TSH2B UBA52 UBA80 UBB UBC UBC9 UBCE9 UBCEP1 UBCEP2 UBE2I UBE2N UBE2V2 UEV2 UIMC1 WHSC1 WRN
G2/M DNA damage checkpoint	ATR-interacting protein BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Cellular tumor antigen p53 Checkpoint protein HUS1 DNA endonuclease RBBP8 DNA repair protein RAD50 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase HERC2 E3 ubiquitin-protein ligase RNF168 E3 ubiquitin-protein ligase RNF8 Exonuclease 1 Fanconi anemia group J protein Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H4 Histone acetyltransferase KAT5 Histone-lysine N-methyltransferase NSD2 Lys-63-specific deubiquitinase BRCC36 Mediator of DNA damage checkpoint protein 1 Nibrin RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine-protein kinase ATM Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1 Serine/threonine-protein kinase Chk2 TP53-binding protein 1 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2	O14757 O60671 O60814 O60921 O60934 O75943 O76064 O95714 O96017 O96028 P04637 P06899 P15927 P16104 P23527 P27694 P33778 P35244 P35249 P35250 P38398 P40937 P40938 P46736 P49959 P51530 P54132 P57053 P58876 P61088 P62805 P62807 Q12888 Q13315 Q13472 Q13535 Q14191 Q14676 Q15819 Q16695 Q16778 Q6UWZ7 Q6WBX8 Q8IYW5 Q8N257 Q8N2W9 Q8WXE1 Q92547 Q92878 Q92993 Q93079 Q96A08 Q96E14 Q96RL1 Q99638 Q99708 Q99728 Q99877 Q99879 Q99880 Q9BSD3 Q9BX63 Q9H9A7 Q9NWV8 Q9NXR7 Q9UQ84	ABRA1 ABRAXAS1 AGS1 ATM ATR ATRIP BABAM1 BABAM2 BACH1 BARD1 BLM BLU BRCA1 BRCC3 BRCC36 BRCC45 BRE BRIP1 C12orf32 C16orf75 C19orf62 C6.1A C9orf76 CCDC98 CDS1 CHEK1 CHEK2 CHK1 CHK2 CTIP CXorf53 DNA2 DNA2L EXO1 EXOI FAM175A FANCJ FRP1 H2AFX H2AX H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-4 H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HERC2 HEX1 HIRIP1 HIRIP2 HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 HNGS1 HTATIP HUS1 KAT5 KIAA0083 KIAA0170 KIAA0259 KIAA0646 KIAA1090 MDC1 MERIT40 MMS2 MMSET MRE11 MRE11A NBA1 NBN NBS NBS1 NFBD1 NSD2 P53 P95 PIAS4 PIASG R24L RAD1 RAD17 RAD50 RAD53 RAD9A RAD9B RAP80 RBBP8 REC1 RECQ2 RECQ3 RECQL2 RECQL3 REPA1 REPA2 REPA3 RFC2 RFC3 RFC4 RFC5 RHINO RHNO1 RMI1 RMI2 RNF168 RNF53 RNF8 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RXRIP110 TIP60 TOP3 TOP3A TOPBP1 TP53 TP53BP1 TRX5 TSH2B UBE2N UBE2V2 UEV2 UIMC1 WHSC1 WRN
Nonhomologous End-Joining (NHEJ)	BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Breast cancer type 1 susceptibility protein DNA ligase 4 DNA polymerase lambda DNA repair protein RAD50 DNA repair protein XRCC4 DNA-dependent protein kinase catalytic subunit DNA-directed DNA/RNA polymerase mu Double-strand break repair protein MRE11 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase HERC2 E3 ubiquitin-protein ligase RNF168 E3 ubiquitin-protein ligase RNF8 Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H4 Histone acetyltransferase KAT5 Histone-lysine N-methyltransferase NSD2 Lys-63-specific deubiquitinase BRCC36 Mediator of DNA damage checkpoint protein 1 Nibrin Non-homologous end-joining factor 1 PAX-interacting protein 1 Protein artemis Serine-protein kinase ATM TP53-binding protein 1 Telomere-associated protein RIF1 Tyrosyl-DNA phosphodiesterase 1 Tyrosyl-DNA phosphodiesterase 2 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2 X-ray repair cross-complementing protein 5 X-ray repair cross-complementing protein 6	O60814 O60934 O76064 O95551 O95714 O96028 P06899 P12956 P13010 P16104 P23527 P33778 P38398 P46736 P49917 P49959 P57053 P58876 P61088 P62805 P62807 P78527 Q12888 Q13315 Q13426 Q14676 Q15819 Q16695 Q16778 Q5UIP0 Q6UWZ7 Q6ZW49 Q8IYW5 Q8N257 Q8N2W9 Q92878 Q92993 Q93079 Q96A08 Q96RL1 Q96SD1 Q99728 Q99877 Q99879 Q99880 Q9H9Q4 Q9NP87 Q9NUW8 Q9NWV8 Q9NXR7 Q9UGP5	ABRA1 ABRAXAS1 ARTEMIS ASCID ATM BABAM1 BABAM2 BARD1 BLU BRCA1 BRCC3 BRCC36 BRCC45 BRE C19orf62 C6.1A CCDC98 CXorf53 DCLRE1C EAP2 FAM175A G22P1 G22P2 H2AFX H2AX H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-4 H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HERC2 HIRIP1 HIRIP2 HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 HNGS1 HTATIP HYRC HYRC1 KAT5 KIAA0170 KIAA0646 KIAA1090 LIG4 MDC1 MERIT40 MMS2 MMSET MRE11 MRE11A NBA1 NBN NBS NBS1 NFBD1 NHEJ1 NSD2 P95 PAXIP1 PAXIP1L PIAS4 PIASG POLL POLM PRKDC PTIP RAD50 RAP80 RIF1 RNF168 RNF53 RNF8 RXRIP110 SCIDA SNM1C TDP1 TDP2 TIP60 TP53BP1 TRX5 TSH2B TTRAP UBE2N UBE2V2 UEV2 UIMC1 WHSC1 XLF XRCC4 XRCC5 XRCC6 polmu
pre-mRNA splicing	116 kDa U5 small nuclear ribonucleoprotein component 17S U2 SnRNP complex component HTATSF1 ATP-dependent RNA helicase A ATP-dependent RNA helicase DDX42 ATP-dependent RNA helicase DHX15 ATP-dependent RNA helicase DHX8 Apoptotic chromatin condensation inducer in the nucleus BUD13 homolog Beta-catenin-like protein 1 CWF19-like protein 2 Calcium homeostasis endoplasmic reticulum protein Cell division cycle 5-like protein Cell division cycle and apoptosis regulator protein 1 Coiled-coil domain-containing protein 12 Crooked neck-like protein 1 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 DnaJ homolog subfamily C member 8 E3 ubiquitin-protein ligase RNF113A Eukaryotic initiation factor 4A-III Exosome RNA helicase MTR4 G patch domain-containing protein 1 G-patch domain and KOW motifs-containing protein General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Heat shock cognate 71 kDa protein Heterogeneous nuclear ribonucleoprotein A1 Heterogeneous nuclear ribonucleoprotein A3 Heterogeneous nuclear ribonucleoprotein D0 Heterogeneous nuclear ribonucleoprotein F Heterogeneous nuclear ribonucleoprotein H2 Heterogeneous nuclear ribonucleoprotein H Heterogeneous nuclear ribonucleoprotein K Heterogeneous nuclear ribonucleoprotein L Heterogeneous nuclear ribonucleoprotein M Heterogeneous nuclear ribonucleoprotein R Heterogeneous nuclear ribonucleoprotein U Heterogeneous nuclear ribonucleoproteins A2/B1 Heterogeneous nuclear ribonucleoproteins C1/C2 Histone deacetylase complex subunit SAP18 Intron Large complex component GCFC2 Leukocyte receptor cluster member 1 Luc7-like protein 3 Microfibrillar-associated protein 1 NF-kappa-B-activating protein NHP2-like protein 1 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Nuclear inhibitor of protein phosphatase 1 Nuclear speckle splicing regulatory protein 1 PHD finger-like domain-containing protein 5A PRKR-interacting protein 1 Peptidyl-prolyl cis-trans isomerase E Peptidyl-prolyl cis-trans isomerase G Peptidyl-prolyl cis-trans isomerase H Peptidyl-prolyl cis-trans isomerase-like 1 Peptidyl-prolyl cis-trans isomerase-like 3 Peptidyl-prolyl cis-trans isomerase-like 4 Peptidylprolyl isomerase domain and WD repeat-containing protein 1 Pinin Pleiotropic regulator 1 Poly(U)-binding-splicing factor PUF60 Poly(rC)-binding protein 1 Poly(rC)-binding protein 2 Polyglutamine-binding protein 1 Polypyrimidine tract-binding protein 1 Pre-mRNA-processing factor 17 Pre-mRNA-processing factor 19 Pre-mRNA-processing factor 40 homolog A Pre-mRNA-processing factor 6 Pre-mRNA-processing-splicing factor 8 Pre-mRNA-splicing factor 18 Pre-mRNA-splicing factor 38A Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 Pre-mRNA-splicing factor CWC22 homolog Pre-mRNA-splicing factor CWC25 homolog Pre-mRNA-splicing factor ISY1 homolog Pre-mRNA-splicing factor RBM22 Pre-mRNA-splicing factor SLU7 Pre-mRNA-splicing factor SPF27 Pre-mRNA-splicing factor SYF1 Pre-mRNA-splicing factor SYF2 Probable ATP-dependent RNA helicase DDX23 Probable ATP-dependent RNA helicase DDX41 Probable ATP-dependent RNA helicase DDX46 Probable ATP-dependent RNA helicase DDX5 Probable ATP-dependent RNA helicase DHX35 Proline-rich protein PRCC Protein BUD31 homolog Protein CASC3 Protein FAM32A Protein FAM50A Protein Red Protein mago nashi homolog 2 Protein mago nashi homolog RING-type E3 ubiquitin-protein ligase PPIL2 RNA helicase aquarius RNA-binding motif protein, X chromosome RNA-binding motif protein, X-linked 2 RNA-binding protein 10 RNA-binding protein 25 RNA-binding protein 39 RNA-binding protein 42 RNA-binding protein 5 RNA-binding protein 7 RNA-binding protein 8A RNA-binding protein FUS RNA-binding protein with serine-rich domain 1 Regulator of nonsense transcripts 3B SNW domain-containing protein 1 STING ER exit protein SURP and G-patch domain-containing protein 1 Serine/arginine repetitive matrix protein 1 Serine/arginine repetitive matrix protein 2 Serine/arginine-rich splicing factor 10 Serine/arginine-rich splicing factor 11 Serine/arginine-rich splicing factor 12 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 3 Serine/arginine-rich splicing factor 4 Serine/arginine-rich splicing factor 5 Serine/arginine-rich splicing factor 6 Serine/arginine-rich splicing factor 7 Serine/arginine-rich splicing factor 8 Serine/arginine-rich splicing factor 9 Serine/threonine-protein kinase PRP4 homolog Serrate RNA effector molecule homolog Smad nuclear-interacting protein 1 Small nuclear ribonucleoprotein E Small nuclear ribonucleoprotein F Small nuclear ribonucleoprotein G Small nuclear ribonucleoprotein Sm D1 Small nuclear ribonucleoprotein Sm D2 Small nuclear ribonucleoprotein Sm D3 Small nuclear ribonucleoprotein-associated protein N Small nuclear ribonucleoprotein-associated proteins B and B' Spliceosome RNA helicase DDX39B Spliceosome-associated protein CWC15 homolog Spliceosome-associated protein CWC27 homolog Splicing factor 1 Splicing factor 3A subunit 1 Splicing factor 3A subunit 2 Splicing factor 3A subunit 3 Splicing factor 3B subunit 1 Splicing factor 3B subunit 2 Splicing factor 3B subunit 3 Splicing factor 3B subunit 4 Splicing factor 3B subunit 5 Splicing factor 3B subunit 6 Splicing factor 45 Splicing factor C9orf78 Splicing factor Cactin Splicing factor U2AF 26 kDa subunit Splicing factor U2AF 35 kDa subunit Splicing factor U2AF 65 kDa subunit Splicing factor YJU2 Splicing regulator SDE2 Survival of motor neuron-related-splicing factor 30 THO complex subunit 4 Thioredoxin-like protein 4A Transcription elongation regulator 1 Transformer-2 protein homolog beta Tuftelin-interacting protein 11 U1 small nuclear ribonucleoprotein 70 kDa U1 small nuclear ribonucleoprotein A U1 small nuclear ribonucleoprotein C U2 small nuclear ribonucleoprotein A' U2 small nuclear ribonucleoprotein B'' U2 snRNP-associated SURP motif-containing protein U4/U6 small nuclear ribonucleoprotein Prp31 U4/U6 small nuclear ribonucleoprotein Prp3 U4/U6 small nuclear ribonucleoprotein Prp4 U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein U4/U6.U5 tri-snRNP-associated protein 1 U5 small nuclear ribonucleoprotein 200 kDa helicase U5 small nuclear ribonucleoprotein 40 kDa protein U6 snRNA-associated Sm-like protein LSm2 U6 snRNA-associated Sm-like protein LSm3 U6 snRNA-associated Sm-like protein LSm4 U6 snRNA-associated Sm-like protein LSm5 U6 snRNA-associated Sm-like protein LSm6 U6 snRNA-associated Sm-like protein LSm7 U6 snRNA-associated Sm-like protein LSm8 Ubiquitin carboxyl-terminal hydrolase 39 Ubiquitin-like protein 5 WD repeat-containing protein 70 WD40 repeat-containing protein SMU1 WW domain-binding protein 11 WW domain-binding protein 4 Y-box-binding protein 1 Zinc finger matrin-type protein 2 Zinc finger protein 830	O00422 O14776 O15042 O15234 O15514 O15541 O43143 O43172 O43290 O43390 O43395 O43447 O43660 O43719 O60231 O60306 O60508 O60828 O75400 O75494 O75533 O75554 O75643 O75934 O75937 O75940 O94906 O95232 O95391 O95777 O95926 P07910 P08579 P08621 P09012 P09234 P09651 P09661 P11142 P13984 P14678 P14866 P16383 P17844 P19387 P19388 P22626 P24928 P26368 P26599 P30876 P31943 P35269 P35637 P36954 P38159 P38919 P41223 P42285 P49756 P51991 P52272 P52298 P52434 P52435 P52597 P52756 P53803 P55081 P55769 P55795 P61218 P61326 P61978 P62304 P62306 P62308 P62310 P62312 P62314 P62316 P62318 P62487 P62875 P62995 P63162 P67809 P83876 P84103 P98175 Q00839 Q01081 Q01130 Q05519 Q07955 Q08170 Q08211 Q09161 Q12874 Q12972 Q13123 Q13242 Q13243 Q13247 Q13356 Q13427 Q13435 Q13523 Q13573 Q13838 Q14103 Q14320 Q14498 Q14562 Q15029 Q15287 Q15365 Q15366 Q15393 Q15427 Q15428 Q15459 Q15637 Q16629 Q2TAY7 Q2TBE0 Q53GS9 Q6IQ49 Q6P2Q9 Q6UX04 Q7L014 Q7RTV0 Q86V81 Q86XP3 Q8IWX8 Q8IWZ8 Q8IX12 Q8IYB3 Q8N5F7 Q8NAV1 Q8TAD8 Q8WU68 Q8WUA2 Q8WUD4 Q8WUQ7 Q8WVK2 Q8WWY3 Q8WXF0 Q8WYA6 Q92620 Q92733 Q92917 Q96A72 Q96BP3 Q96BZ8 Q96DI7 Q96I25 Q96NB3 Q96NC0 Q99459 Q99633 Q9BRD0 Q9BRL6 Q9BRR8 Q9BTD8 Q9BUQ8 Q9BW85 Q9BWJ5 Q9BXP5 Q9BZI7 Q9BZJ0 Q9BZL1 Q9H0G5 Q9H2H8 Q9H307 Q9H5V9 Q9H5Z1 Q9H875 Q9HCG8 Q9HCS7 Q9NW64 Q9NW82 Q9NXE8 Q9NZ63 Q9P013 Q9UBB9 Q9UHX1 Q9UJV9 Q9UK45 Q9UKV3 Q9ULR0 Q9UMS4 Q9UNP9 Q9UQ35 Q9Y2W2 Q9Y333 Q9Y388 Q9Y3B4 Q9Y3C6 Q9Y421 Q9Y4Y9 Q9Y4Z0 Q9Y580 Q9Y5S9	ABS ACIN1 ACINUS ALY ALYREF AQR ARD1 ARS2 ASCC3L1 ASF ASR2 AUF1 BAT1 BCAS2 BEF BRR2 BUD13 BUD31 C11orf5 C19orf29 C1orf199 C1orf55 C20orf14 C20orf15 C20orf33 C2orf3 C6orf28 C9orf78 CA150 CACTIN CARP1 CASC3 CBP20 CBP80 CBPIN CCAR1 CCDC12 CCDC16 CCDC49 CCDC55 CCDC94 CDC40 CDC5L CHERP COD CREAP1 CRN CRNKL1 CROP CTNNBL1 CWC15 CWC22 CWC25 CWC27 CWF19L2 CXorf56 CYP20 CYP33 CYPH CYPL1 DAM1 DAN26 DBP1 DBP2 DDX15 DDX16 DDX23 DDX35 DDX38 DDX39B DDX41 DDX42 DDX46 DDX48 DDX5 DDX8 DDX9 DHX15 DHX16 DHX35 DHX38 DHX8 DHX9 DIM1 DIS DNAJC8 DOB1 DRS DXS8237E DXS9928E ECGP EDG2 EFTUD2 EHB3 EIF4A3 FAM32A FAM50A FBP11 FBP21 FIR FLAF1 FNBP21 FNBP3 FTP3 FUS FUSIP1 FUSIP2 G17P1 G7B GCF GCFC2 GCIPIP GPATC1 GPATC5 GPATC9 GPATCH1 GPATCH5 GPATCH9 GPKOW GTF2F1 GTF2F2 HCA59 HCC1 HCERN3 HCNP HELIC2 HELR HIP10 HLR1 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPL HNRNPM HNRNPR HNRNPU HNRPA1 HNRPA2B1 HNRPA3 HNRPC HNRPD HNRPF HNRPG HNRPH HNRPH1 HNRPH2 HNRPK HNRPL HNRPM HNRPR HNRPU HPRP18 HPRP3 HRS HSC70 HSP73 HSPA10 HSPA8 HTATSF1 HXC26 HYPA IK ISY1 KIAA0017 KIAA0031 KIAA0052 KIAA0073 KIAA0111 KIAA0122 KIAA0224 KIAA0324 KIAA0332 KIAA0432 KIAA0536 KIAA0560 KIAA0577 KIAA0670 KIAA0788 KIAA0801 KIAA1160 KIAA1177 KIAA1604 LDC2 LENG1 LKP LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 LSM8 LUC7L3 MAGOH MAGOH2 MAGOHA MAGOHB MEMA MFAP1 MLN51 MTR4 MTREX NAGR1 NCBP NCBP1 NCBP2 NCM NDH2 NHP2L1 NIPP1 NKAP NMP200 NPW38 NPWBP NSEP1 NSRP1 NSRP70 O48 OTAG12 PBSCF PBSCG PCBP1 PCBP2 PCDC5RP PHF5A PLRG1 PNN POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PPIE PPIG PPIH PPIL1 PPIL2 PPIL3 PPIL4 PPP1R8 PPWD1 PQBP1 PRCC PRKRIP1 PRP16 PRP17 PRP19 PRP2 PRP3 PRP31 PRP4 PRP4B PRP4H PRP4K PRP8BP PRPC8 PRPF17 PRPF18 PRPF19 PRPF3 PRPF31 PRPF38A PRPF4 PRPF40A PRPF4K PRPF6 PRPF8 PTB PTBP1 PUF60 RAP30 RAP74 RBM10 RBM17 RBM22 RBM25 RBM39 RBM42 RBM5 RBM7 RBM8 RBM8A RBMX RBMX2 RBMXP1 RED RENT3B RER RNF113 RNF113A RNPC2 RNPC7 RNPS1 RNPU1Z ROBPI RPB7 RPU1 SAFA SAP114 SAP130 SAP14 SAP145 SAP155 SAP18 SAP49 SAP61 SAP62 SART1 SCAF6 SDCCAG10 SDE2 SF1 SF2 SF2P33 SF3A1 SF3A2 SF3A3 SF3B1 SF3B10 SF3B14 SF3B14A SF3B2 SF3B3 SF3B4 SF3B5 SF3B6 SF4 SFP38 SFRS1 SFRS10 SFRS11 SFRS13A SFRS13B SFRS19 SFRS2 SFRS2B SFRS3 SFRS4 SFRS5 SFRS6 SFRS7 SFRS9 SIAHBP1 SIPP1 SKIIP SKIP SKIV2L2 SLU7 SMN SMNDC1 SMNR SMU1 SNEV SNIP1 SNP70 SNRNP200 SNRNP27 SNRNP40 SNRNP70 SNRP116 SNRP70 SNRPA SNRPA1 SNRPB SNRPB1 SNRPB2 SNRPC SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNRPN SNU13 SNW1 SPF30 SPF31 SPF45 SR140 SRL300 SRM160 SRM300 SRP20 SRP30C SRP40 SRP46 SRP55 SRP75 SRRM1 SRRM2 SRRP35 SRRT SRSF1 SRSF10 SRSF11 SRSF12 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SRSF9 STEEP1 STIP SUGP1 SYF1 SYF2 T54 TAF2S TASR TCERG1 TCF9 TFIP11 THOC4 TLS TPRC TRA2B TXNL4 TXNL4A U1AP1 U21.1 U2AF1 U2AF1-RS3 U2AF1L3 U2AF1L4 U2AF2 U2AF35 U2AF65 U2AFBP U2SURP UAP56 UBL5 UPF3B UPF3X USP39 WBP11 WBP4 WDR57 WDR70 XAB2 XAP5 YB1 YBX1 YJU2 ZC3H16 ZFM1 ZMAT2 ZNF162 ZNF183 ZNF830
Regulation of innate immune responses to cytosolic DNA	E3 ubiquitin-protein ligase DTX4 E3 ubiquitin-protein ligase TRIM21 E3 ubiquitin-protein ligase TRIM32 E3 ubiquitin-protein ligase TRIM56 Interferon regulatory factor 3 NACHT, LRR and PYD domains-containing protein 4 Polyubiquitin-B Polyubiquitin-C Probable ATP-dependent RNA helicase DDX41 Serine/threonine-protein kinase TBK1 Stimulator of interferon genes protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Z-DNA-binding protein 1	P0CG47 P0CG48 P19474 P62979 P62987 Q13049 Q14653 Q86WV6 Q96MN2 Q9BRZ2 Q9H171 Q9UHD2 Q9UJV9 Q9Y2E6	ABS C20orf183 DDX41 DLM1 DTX4 ERIS HT2A IRF3 KIAA0937 MITA NAK NALP4 NLRP4 PAN2 PYPAF4 RNF109 RNF155 RNF81 RNH2 RO52 RPS27A SSA1 STING STING1 TBK1 TMEM173 TRIM21 TRIM32 TRIM56 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 ZBP1
STING mediated induction of host immune responses	Cyclic GMP-AMP synthase E3 ubiquitin-protein ligase TRIM21 Gamma-interferon-inducible protein 16 Probable ATP-dependent RNA helicase DDX41 Stimulator of interferon genes protein	P19474 Q16666 Q86WV6 Q8N884 Q9UJV9	ABS C6orf150 CGAS DDX41 ERIS IFI16 IFNGIP1 MB21D1 MITA RNF81 RO52 SSA1 STING STING1 TMEM173 TRIM21
IRF3-mediated induction of type I IFN	DNA-dependent protein kinase catalytic subunit Double-strand break repair protein MRE11 E3 ubiquitin-protein ligase DTX4 Gamma-interferon-inducible protein 16 Interferon regulatory factor 3 NACHT, LRR and PYD domains-containing protein 4 NLR family CARD domain-containing protein 3 Probable ATP-dependent RNA helicase DDX41 Serine/threonine-protein kinase TBK1 Stimulator of interferon genes protein Three-prime repair exonuclease 1 X-ray repair cross-complementing protein 5 X-ray repair cross-complementing protein 6	P12956 P13010 P49959 P78527 Q14653 Q16666 Q7RTR2 Q86WV6 Q96MN2 Q9NSU2 Q9UHD2 Q9UJV9 Q9Y2E6	ABS DDX41 DTX4 ERIS G22P1 G22P2 HNGS1 HYRC HYRC1 IFI16 IFNGIP1 IRF3 KIAA0937 MITA MRE11 MRE11A NAK NALP4 NLRC3 NLRP4 NOD3 PAN2 PRKDC PYPAF4 RNF155 RNH2 STING STING1 TBK1 TMEM173 TREX1 XRCC5 XRCC6
Peroxisomal protein import	2-Hydroxyacid oxidase 1 2-Hydroxyacid oxidase 2 2-hydroxyacyl-CoA lyase 1 3-ketoacyl-CoA thiolase, peroxisomal AN1-type zinc finger protein 6 Acyl-coenzyme A diphosphatase NUDT19 Acyl-coenzyme A thioesterase 2, mitochondrial Acyl-coenzyme A thioesterase 8 Alanine--glyoxylate aminotransferase Alkyldihydroxyacetonephosphate synthase, peroxisomal Alpha-methylacyl-CoA racemase Bifunctional epoxide hydrolase 2 Bile acid-CoA Carnitine O-acetyltransferase Catalase D-amino-acid oxidase D-aspartate oxidase Dehydrogenase/reductase SDR family member 4 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial Dihydroxyacetone phosphate acyltransferase Glutathione S-transferase kappa 1 Hydroxymethylglutaryl-CoA lyase, mitochondrial Insulin-degrading enzyme Isocitrate dehydrogenase [NADP] cytoplasmic Lon protease homolog 2, peroxisomal Long-chain fatty acid transport protein 2 Nitric oxide synthase, inducible Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] Peroxisomal ATPase PEX1 Peroxisomal ATPase PEX6 Peroxisomal N(1)-acetyl-spermine/spermidine oxidase Peroxisomal acyl-coenzyme A oxidase 1 Peroxisomal acyl-coenzyme A oxidase 2 Peroxisomal acyl-coenzyme A oxidase 3 Peroxisomal bifunctional enzyme Peroxisomal carnitine O-octanoyltransferase Peroxisomal coenzyme A diphosphatase NUDT7 Peroxisomal leader peptide-processing protease Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisomal multifunctional enzyme type 2 Peroxisomal sarcosine oxidase Peroxisomal succinyl-coenzyme A thioesterase Peroxisomal targeting signal 2 receptor Peroxisomal trans-2-enoyl-CoA reductase Peroxisome assembly protein 12 Peroxisome assembly protein 26 Peroxisome biogenesis factor 10 Peroxisome biogenesis factor 2 Phytanoyl-CoA dioxygenase, peroxisomal Polyubiquitin-B Polyubiquitin-C Protein Mpv17 Sterol carrier protein 2 Ubiquitin carboxyl-terminal hydrolase 9X Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A8MXV4 O00116 O00623 O00628 O14734 O14832 O14975 O15228 O15254 O43933 O60683 O75381 O75874 P04040 P09110 P0C024 P0CG47 P0CG48 P14735 P14920 P21549 P22307 P28328 P34913 P35228 P35914 P39210 P43155 P49753 P51659 P51668 P61077 P62837 P62979 P62987 Q08426 Q13011 Q13608 Q14032 Q15067 Q2T9J0 Q6FIF0 Q6QHF9 Q7Z412 Q86WA8 Q8N9L9 Q92968 Q93008 Q99424 Q99489 Q9BTZ2 Q9BY49 Q9NUI1 Q9NYQ3 Q9P0Z9 Q9UHK6 Q9UJ83 Q9UJM8 Q9UKG9 Q9Y2Q3	ACAA ACAA1 ACOT2 ACOT4 ACOT8 ACOX ACOX1 ACOX2 ACOX3 ACSVL1 ACTEIII AGPS AGT1 AGXT AMACR AWP1 BAAT BRCOX CAT CAT1 COT CRAT CROT DAMOX DAO DAPAT DDO DECR2 DFFRX DHAPAT DHRS4 ECH1 ECHD EDH17B4 EHHADH EPHX2 FACVL1 FAM FATP2 GNPAT GOX1 GSTK1 HACL1 HAO1 HAO2 HAOX2 HMGCL HPCL HPCL2 HSD17B4 IDE IDH1 LONP LONP2 LPIPOX MPV17 NOS2 NOS2A NUDT19 NUDT7 PAF1 PAF3 PAHX PAO PAOX PDCR PECR PEX1 PEX10 PEX12 PEX13 PEX14 PEX2 PEX26 PEX6 PEX7 PHYH PHYH2 PICD PIPOX PMP3 PMP35 PRCOX PSO PTE1 PTE2 PTE2A PTE2B PTEIB PTHIO PTS2R PUBC1 PXAAA1 PXMP3 RNF69 RNF72 RPS27A SCP2 SDR17C1 SDR25C2 SDR29C1 SDR8C1 SFT SLC27A2 SPAT TYSND1 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBE2D1 UBE2D2 UBE2D3 USP9 USP9X VLACS ZA20D3 ZFAND6
TYSND1 cleaves peroxisomal proteins	3-ketoacyl-CoA thiolase, peroxisomal Alkyldihydroxyacetonephosphate synthase, peroxisomal Peroxisomal acyl-coenzyme A oxidase 1 Peroxisomal leader peptide-processing protease Peroxisomal multifunctional enzyme type 2 Phytanoyl-CoA dioxygenase, peroxisomal Sterol carrier protein 2	O00116 O14832 P09110 P22307 P51659 Q15067 Q2T9J0	ACAA ACAA1 ACOX ACOX1 AGPS EDH17B4 HSD17B4 PAHX PHYH PTHIO SCP2 SDR8C1 TYSND1
Mitochondrial Fatty Acid Beta-Oxidation	3-ketoacyl-CoA thiolase, mitochondrial Acetyl-coenzyme A thioesterase Acyl carrier protein, mitochondrial Acyl-CoA dehydrogenase family member 10 Acyl-CoA dehydrogenase family member 11 Acyl-CoA-binding domain-containing protein 6 Acyl-CoA-binding domain-containing protein 7 Acyl-CoA-binding protein Acyl-coenzyme A thioesterase 11 Acyl-coenzyme A thioesterase 13 Acyl-coenzyme A thioesterase 1 Acyl-coenzyme A thioesterase 2, mitochondrial Acyl-coenzyme A thioesterase 9, mitochondrial Acyl-coenzyme A thioesterase THEM4 Acyl-coenzyme A thioesterase THEM5 Cytosolic acyl coenzyme A thioester hydrolase Malonyl-CoA-acyl carrier protein transacylase, mitochondrial Medium-chain acyl-CoA ligase ACSF2, mitochondrial Phosphatidylcholine transfer protein Putative cytosolic acyl coenzyme A thioester hydrolase-like	O00154 O14561 P07108 P42765 P49753 Q5T1C6 Q6JQN1 Q6ZUV0 Q709F0 Q86TX2 Q8IVS2 Q8N1Q8 Q8N6N7 Q8WXI4 Q8WYK0 Q96CM8 Q9BR61 Q9NPJ3 Q9UKL6 Q9Y305	ACAA2 ACAD10 ACAD11 ACBD6 ACBD7 ACOT1 ACOT11 ACOT12 ACOT13 ACOT15 ACOT2 ACOT7 ACOT7L ACOT9 ACSF2 BACH BACHL BFIT CACH CACH1 CTE1 CTMP DBI KIAA0707 MCAT MT NDUFAB1 PCTP PTE2 PTE2A STARD15 STARD2 THEA THEM2 THEM4 THEM5
ChREBP activates metabolic gene expression	1-acyl-sn-glycerol-3-phosphate acyltransferase alpha ATP-citrate synthase Acetyl-CoA carboxylase 1 Acetyl-CoA carboxylase 2 Carbohydrate-responsive element-binding protein Fatty acid synthase Max-like protein X	O00763 P49327 P53396 Q13085 Q99943 Q9NP71 Q9UH92	ACAC ACACA ACACB ACC1 ACC2 ACCA ACCB ACLY AGPAT1 BHLHD13 BHLHD14 FAS FASN G15 MIO MLX MLXIPL TCFL4 WBSCR14
Activation of gene expression by SREBF (SREBP)	3'-5' exoribonuclease HELZ2 7-dehydrocholesterol reductase Acetyl-CoA carboxylase 1 Acetyl-CoA carboxylase 2 CREB-binding protein Chromodomain-helicase-DNA-binding protein 9 Delta(14)-sterol reductase TM7SF2 Diphosphomevalonate decarboxylase F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Farnesyl pyrophosphate synthase Fatty acid synthase Geranylgeranyl pyrophosphate synthase Glycerol-3-phosphate acyltransferase 1, mitochondrial Histone-arginine methyltransferase CARM1 Hydroxymethylglutaryl-CoA synthase, cytoplasmic Isopentenyl-diphosphate Delta-isomerase 1 Lanosterol 14-alpha demethylase Lanosterol synthase Lathosterol oxidase Mediator of RNA polymerase II transcription subunit 1 Metal regulatory transcription factor 1 Mevalonate kinase Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Nuclear transcription factor Y subunit alpha Nuclear transcription factor Y subunit beta Nuclear transcription factor Y subunit gamma Peroxisome proliferator-activated receptor alpha Phosphomevalonate kinase Retinoic acid receptor RXR-alpha SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Squalene monooxygenase Squalene synthase Stearoyl-CoA desaturase Sterol regulatory element-binding protein 2 Transcription factor Sp1 Trimethylguanosine synthase Very long chain fatty acid elongase 6	O00763 O00767 O60907 O75845 O76062 O95749 P08047 P14324 P19793 P23511 P25208 P37268 P48449 P49327 P53602 Q01581 Q03426 Q07869 Q12772 Q13085 Q13907 Q13952 Q14534 Q14686 Q14872 Q15126 Q15596 Q15648 Q15788 Q16850 Q3L8U1 Q6STE5 Q86X55 Q92793 Q96RS0 Q9BYK8 Q9BZK7 Q9H5J4 Q9HCL2 Q9UBM7	ACAC ACACA ACACB ACC1 ACC2 ACCA ACCB AIB3 ANG1 ARC205 BAF60C BHLHD2 BHLHE74 BHLHE75 CARM1 CBP CHD9 CREBBP CRSP1 CRSP200 CYP51 CYP51A1 D7SR DHCR7 DRIP205 DRIP230 ELOVL6 ERG1 FACE FADS5 FAS FASN FDFT1 FDPS FPS GGPS1 GPAM GPAT1 HAP3 HCA137 HELZ2 HMGCS HMGCS1 IDI1 IRA1 KIAA0181 KIAA0308 KIAA1293 KIAA1560 KIAA1769 KISH2 LCE LSS MED1 MPD MTF1 MVD MVK NCOA1 NCOA2 NCOA6 NCOA6IP NFYA NFYB NFYC NR1C1 NR2B1 OSC PBP PIMT PMKI PMVK PPAR PPARA PPARBP PPARGBP PRIC285 PRIC320 PRMT4 RAP250 RB18A RXRA SC5D SC5DL SCD SCD1 SCDOS SMARCD3 SP1 SQLE SRC1 SRC2 SREBF2 SREBP2 TBL1 TBL1X TBL1XR1 TBLR1 TGS1 TIF2 TM7SF2 TRAP220 TRBP TRIP2 TSFP1
Biotin transport and metabolism	Acetyl-CoA carboxylase 1 Acetyl-CoA carboxylase 2 Biotin--protein ligase Biotinidase Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial PDZ domain-containing protein 11 Propionyl-CoA carboxylase alpha chain, mitochondrial Propionyl-CoA carboxylase beta chain, mitochondrial Pyruvate carboxylase, mitochondrial Sodium-dependent multivitamin transporter	O00763 P05165 P05166 P11498 P43251 P50747 Q13085 Q5EBL8 Q96RQ3 Q9HCC0 Q9Y289	ACAC ACACA ACACB ACC1 ACC2 ACCA ACCB AIPP1 BTD HLCS MCCA MCCB MCCC1 MCCC2 PC PCCA PCCB PDZD11 PDZK11 PISP SLC5A6 SMVT
Fatty acyl-CoA biosynthesis	(3R)-3-hydroxyacyl-CoA dehydrogenase 3-oxoacyl-[acyl-carrier-protein] reductase ATP-citrate synthase ATPase MORC2 Acetyl-CoA carboxylase 1 Fatty acid synthase Hydroxyacyl-thioester dehydratase type 2, mitochondrial Long-chain fatty acid transport protein 2 Lysosomal thioesterase PPT2 Palmitoyl-protein thioesterase 1 S-acyl fatty acid synthase thioesterase, medium chain Stearoyl-CoA desaturase 5 Stearoyl-CoA desaturase	O00767 O14975 P49327 P50897 P53396 P86397 Q13085 Q86SK9 Q8N4T8 Q92506 Q9NV23 Q9UMR5 Q9Y6X9	ACAC ACACA ACC1 ACCA ACLY ACOD4 ACSVL1 CBR4 CLN1 FABGL FACVL1 FADS5 FAS FASN FATP2 HKE6 HSD17B8 HTD2 KIAA0852 MORC2 OLAH PPT PPT1 PPT2 RING2 SCD SCD1 SCD2 SCD4 SCD5 SCDOS SDR30C1 SDR45C1 SLC27A2 THEDC1 VLACS ZCWCC1
Defective HLCS causes multiple carboxylase deficiency	Acetyl-CoA carboxylase 1 Biotin--protein ligase Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial Propionyl-CoA carboxylase alpha chain, mitochondrial Propionyl-CoA carboxylase beta chain, mitochondrial Pyruvate carboxylase, mitochondrial	P05165 P05166 P11498 P50747 Q13085 Q96RQ3 Q9HCC0	ACAC ACACA ACC1 ACCA HLCS MCCA MCCB MCCC1 MCCC2 PC PCCA PCCB
Branched-chain amino acid catabolism	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial 3-hydroxyacyl-CoA dehydrogenase type-2 3-hydroxyisobutyrate dehydrogenase, mitochondrial 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial Acetyl-CoA acetyltransferase, mitochondrial Branched-chain alpha-ketoacid dehydrogenase kinase Branched-chain-amino-acid aminotransferase, cytosolic Branched-chain-amino-acid aminotransferase, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Enoyl-CoA hydratase, mitochondrial Isobutyryl-CoA dehydrogenase, mitochondrial Isovaleryl-CoA dehydrogenase, mitochondrial Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial Methylglutaconyl-CoA hydratase, mitochondrial Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial Protein phosphatase Mn(2+)-dependent 1K Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial Solute carrier family 25 member 44	O14874 O15382 P09622 P11182 P12694 P21953 P24752 P26440 P30084 P31937 P45954 P54687 Q02252 Q13825 Q6NVY1 Q8N3J5 Q96H78 Q96RQ3 Q99714 Q9HCC0 Q9UKU7	ACAD8 ACADSB ACAT ACAT1 ALDH6A1 ARC42 AUH BCAT1 BCAT2 BCATE2 BCATM BCKDHA BCKDHB BCKDHE2 BCKDK BCT1 BCT2 DBT DLD ECA39 ECA40 ECHS1 ERAB GCSL HADH2 HIBADH HIBCH HSD17B10 IBD IVD KIAA0446 LAD MAT MCCA MCCB MCCC1 MCCC2 MMSDH MRPP2 PHE3 PP2CM PPM1K SCHAD SDR5C1 SLC25A44 XH98G2
Complex I biogenesis	Acyl carrier protein, mitochondrial Arginine-hydroxylase NDUFAF5, mitochondrial Complex I assembly factor ACAD9, mitochondrial Complex I assembly factor TIMMDC1, mitochondrial Complex I assembly factor TMEM126B, mitochondrial Complex I intermediate-associated protein 30, mitochondrial Cytochrome c oxidase assembly factor 1 homolog Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Iron-sulfur cluster transfer protein NUBPL NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NADH dehydrogenase [ubiquinone] 1 subunit C2 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NADH-ubiquinone oxidoreductase chain 1 NADH-ubiquinone oxidoreductase chain 2 NADH-ubiquinone oxidoreductase chain 3 NADH-ubiquinone oxidoreductase chain 4 NADH-ubiquinone oxidoreductase chain 5 NADH-ubiquinone oxidoreductase chain 6 Protein arginine methyltransferase NDUFAF7, mitochondrial Transmembrane protein 186	O00217 O14561 O15239 O43181 O43674 O43676 O43677 O43678 O43920 O75251 O75306 O75380 O75438 O75489 O95139 O95167 O95168 O95169 O95178 O95182 O95298 O95299 O96000 P03886 P03891 P03897 P03905 P03915 P03923 P17568 P19404 P28331 P49821 P51970 P56181 P56556 Q16718 Q16795 Q330K2 Q5TEU4 Q7L592 Q86Y39 Q8IUX1 Q8N183 Q8TB37 Q96B77 Q9BQ95 Q9BU61 Q9GZY4 Q9H845 Q9NPL8 Q9NX14 Q9P032 Q9P0J0 Q9UI09 Q9Y375 Q9Y6M9	ACAD9 C14orf127 C16orf51 C20orf7 C2orf56 C3orf1 C3orf60 C6orf66 C7orf44 C8orf38 CIA30 COA1 DAP13 ECSIT GRIM19 HRPAP20 LYRM3 LYRM6 MITRAC15 MT-ND1 MT-ND2 MT-ND3 MT-ND4 MT-ND5 MT-ND6 MTND1 MTND2 MTND3 MTND4 MTND5 MTND6 NADH1 NADH2 NADH3 NADH4 NADH5 NADH6 NADHB14 ND1 ND2 ND3 ND4 ND5 ND6 NDUFA1 NDUFA10 NDUFA11 NDUFA12 NDUFA12L NDUFA13 NDUFA2 NDUFA3 NDUFA5 NDUFA6 NDUFA7 NDUFA8 NDUFA9 NDUFAB1 NDUFAF1 NDUFAF2 NDUFAF3 NDUFAF4 NDUFAF5 NDUFAF6 NDUFAF7 NDUFB1 NDUFB10 NDUFB11 NDUFB2 NDUFB3 NDUFB4 NDUFB5 NDUFB6 NDUFB7 NDUFB8 NDUFB9 NDUFC1 NDUFC2 NDUFS1 NDUFS2 NDUFS2L NDUFS3 NDUFS4 NDUFS5 NDUFS6 NDUFS7 NDUFS8 NDUFV1 NDUFV2 NDUFV3 NUBPL TIMMDC1 TMEM126B TMEM186 UQOR1 UQOR22
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids	2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial Enoyl-CoA delta isomerase 1, mitochondrial Long-chain specific acyl-CoA dehydrogenase, mitochondrial Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P11310 P28330 P40939 P42126 P55084 Q16698	ACADL ACADM DCI DECR DECR1 ECI1 HADH HADHA HADHB SDR18C1
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA	Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Long-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P28330 P30084 P40939 P55084 Q16836	ACADL ECHS1 HAD HAD1 HADH HADHA HADHB HADHSC SCHAD
Beta oxidation of myristoyl-CoA to lauroyl-CoA	Long-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P28330 P40939 P55084	ACADL HADH HADHA HADHB
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA	Enoyl-CoA hydratase, mitochondrial Enoyl-[acyl-carrier-protein] reductase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P11310 P30084 P40939 P55084 Q16836 Q9BV79	ACADM ECHS1 HAD HAD1 HADH HADHA HADHB HADHSC MECR NBRF1 SCHAD
Beta oxidation of octanoyl-CoA to hexanoyl-CoA	Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P11310 P30084 P40939 P55084 Q16836	ACADM ECHS1 HAD HAD1 HADH HADHA HADHB HADHSC SCHAD
Beta oxidation of butanoyl-CoA to acetyl-CoA	Acyl-coenzyme A synthetase ACSM3, mitochondrial Acyl-coenzyme A synthetase ACSM6, mitochondrial Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Short-chain specific acyl-CoA dehydrogenase, mitochondrial	P16219 P30084 Q16836 Q53FZ2 Q6P461	ACADS ACSM3 ACSM6 C10orf129 ECHS1 HAD HAD1 HADH HADHSC SAH SCHAD
Beta oxidation of hexanoyl-CoA to butanoyl-CoA	Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Short-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P16219 P30084 P40939 P55084 Q16836	ACADS ECHS1 HAD HAD1 HADH HADHA HADHB HADHSC SCHAD
Beta oxidation of palmitoyl-CoA to myristoyl-CoA	Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	P40939 P49748 P55084	ACADVL HADH HADHA HADHB VLCAD

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