GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1251 - 1275** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism	GlyTouCan ID
Formation of the anterior neural plate	Homeobox protein GBX-2 Homeobox protein NANOG Homeobox protein OTX2 POU domain, class 3, transcription factor 1 POU domain, class 5, transcription factor 1 Paired box protein Pax-6 Transcription factor SOX-1 Transcription factor SOX-2 Zinc finger E-box-binding homeobox 2 Zinc finger protein 521 Zinc finger protein ZIC 2	O00570 O60315 O95409 P26367 P32243 P48431 P52951 Q01860 Q03052 Q96K83 Q9H9S0	AN2 EHZF GBX2 KIAA0569 LIP3 NANOG OCT3 OCT4 OCT6 OTF3 OTF6 OTX2 PAX6 POU3F1 POU5F1 SIP1 SOX1 SOX2 ZEB2 ZFHX1B ZFX1B ZIC2 ZNF521	Homo sapiens (human)
Regulation of gene expression in beta cells	DNA-binding protein RFX6 Forkhead box protein O1 Hepatocyte nuclear factor 1-alpha Hepatocyte nuclear factor 3-beta Hepatocyte nuclear factor 3-gamma Hepatocyte nuclear factor 4-gamma Hexokinase-4 Homeobox protein Nkx-2.2 Homeobox protein Nkx-6.1 Insulin Islet amyloid polypeptide Neurogenic differentiation factor 1 Paired box protein Pax-6 Pancreas/duodenum homeobox protein 1 Solute carrier family 2, facilitated glucose transporter member 2 Transcription factor MafA	O95096 P01308 P10997 P11168 P20823 P26367 P35557 P52945 P55318 P78426 Q12778 Q13562 Q14541 Q8HWS3 Q8NHW3 Q9Y261	AN2 BHLHA3 FKHR FOXA2 FOXA3 FOXO1 FOXO1A GCK GLUT2 HNF1A HNF3B HNF3G HNF4G IAPP INS IPF1 MAFA NEUROD NEUROD1 NKX2-2 NKX2.2 NKX2B NKX6-1 NKX6A NR2A2 PAX6 PDX1 RFX6 RFXDC1 SLC2A2 STF1 TCF1 TCF3B TCF3G	Homo sapiens (human)
Digestion of dietary carbohydrate	Acidic mammalian chitinase Alpha-amylase 1A Alpha-amylase 1B Alpha-amylase 1C Alpha-amylase 2B Chitotriosidase-1 Lactase/phlorizin hydrolase Maltase-glucoamylase Pancreatic alpha-amylase Sucrase-isomaltase, intestinal Trehalase	O43280 O43451 P04746 P09848 P0DTE7 P0DTE8 P0DUB6 P14410 P19961 Q13231 Q9BZP6	AMY1 AMY1A AMY1B AMY1C AMY2A AMY2B CHIA CHIT1 LCT LPH MGA MGAM MGAML SI TREA TREH	Homo sapiens (human)	G58161NS G74621DY G80384UV G93924TT G96370VA
Glycine degradation	2-oxoglutarate dehydrogenase complex component E1 Alpha-ketoglutarate dehydrogenase component 4 Aminomethyltransferase, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial Glycine cleavage system H protein, mitochondrial Glycine dehydrogenase (decarboxylating), mitochondrial	P09622 P23378 P23434 P36957 P48728 P82909 Q02218	AMT DLD DLST DLTS GCSH GCSL GCSP GCST GLDC KGD4 LAD MRPS36 OGDH PHE3	Homo sapiens (human)
Nuclear events mediated by NFE2L2	5'-AMP-activated protein kinase catalytic subunit alpha-2 CREB-binding protein Histone acetyltransferase p300 Kelch-like ECH-associated protein 1 Nuclear factor erythroid 2-related factor 2 Sequestosome-1 Transcription factor MafG Transcription factor MafK Tumor suppressor ARF	O15525 O60675 P54646 Q09472 Q13501 Q14145 Q16236 Q8N726 Q92793	AMPK AMPK2 CBP CDKN2 CDKN2A CREBBP EP300 INRF2 KEAP1 KIAA0132 KLHL19 MAFG MAFK MLM NFE2L2 NRF2 ORCA OSIL P300 PRKAA2 SQSTM1	Homo sapiens (human)
Carnitine shuttle	5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-2 Carnitine O-palmitoyltransferase 1, liver isoform Carnitine O-palmitoyltransferase 1, muscle isoform Carnitine O-palmitoyltransferase 2, mitochondrial Mid1-interacting protein 1 Mitochondrial carnitine/acylcarnitine carrier protein Organic cation/carnitine transporter 2 Peroxisome proliferator-activated receptor delta Retinoic acid receptor RXR-alpha Thyroid hormone-inducible hepatic protein	O43741 O43772 O76082 P19793 P23786 P50416 P54646 Q03181 Q92523 Q92748 Q9NPA3 Q9UGJ0	AMPK AMPK2 CAC CACT CPT1 CPT1A CPT1B CPT2 KIAA1670 MID1IP1 MIG12 NR1C2 NR2B1 OCTN2 PPARB PPARD PRKAA2 PRKAB2 PRKAG2 RXRA SLC22A5 SLC25A20 THRSP	Homo sapiens (human)
Activation of PPARGC1A (PGC-1alpha) by phosphorylation	5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 14 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha	O43741 P53778 P54619 P54646 Q15759 Q16539 Q9UBK2 Q9UGI9 Q9UGJ0 Q9Y478	AMPK AMPK2 AMPKG3 CSBP CSBP1 CSBP2 CSPB1 ERK6 LEM6 MAPK11 MAPK12 MAPK14 MXI2 PGC1 PGC1A PPARGC1 PPARGC1A PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 PRKM11 SAPK2 SAPK2A SAPK2B SAPK3	Homo sapiens (human)
Activation of AMPK downstream of NMDARs	5'-AMP-activated protein kinase catalytic subunit alpha-1 5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 Calcium/calmodulin-dependent protein kinase kinase 2 Calmodulin-1	O43741 P0DP23 P54619 P54646 Q13131 Q96RR4 Q9UGI9 Q9UGJ0 Q9Y478	AMPK AMPK1 AMPK2 AMPKG3 CALM CALM1 CAM CAM1 CAMKK2 CAMKKB KIAA0787 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3	Homo sapiens (human)
Signaling by Hippo	14-3-3 protein beta/alpha 14-3-3 protein epsilon Angiomotin-like protein 1 Angiomotin-like protein 2 Caspase-3 MOB kinase activator 1A MOB kinase activator 1B Nephrocystin-4 Protein KIBRA Protein salvador homolog 1 Segment polarity protein dishevelled homolog DVL-2 Serine/threonine-protein kinase 3 Serine/threonine-protein kinase 4 Serine/threonine-protein kinase LATS1 Serine/threonine-protein kinase LATS2 Tight junction protein ZO-1 Tight junction protein ZO-2 Transcriptional coactivator YAP1 WW domain-containing transcription regulator protein 1	O14641 O75161 O95835 P31946 P42574 P46937 P62258 Q07157 Q13043 Q13188 Q7L9L4 Q8IX03 Q8IY63 Q9GZV5 Q9H4B6 Q9H8S9 Q9NRM7 Q9UDY2 Q9Y2J4	AMOTL1 AMOTL2 C2orf6 CASP3 CPP32 DVL2 KIAA0673 KIAA0869 KIAA0989 KIBRA KPM KRS1 KRS2 LATS1 LATS2 MOB1A MOB1B MOB4A MOB4B MOBK1B MOBKL1A MOBKL1B MST1 MST2 NPHP4 SAV1 STK3 STK4 TAZ TJP1 TJP2 WARTS WW45 WWC1 WWTR1 X104 YAP1 YAP65 YWHAB YWHAE ZO1 ZO2	Homo sapiens (human)
Defective AMN causes MGA1	Cobalamin binding intrinsic factor Cubilin Protein amnionless	O60494 P27352 Q9BXJ7	AMN CBLIF CUBN GIF IFCR IFMH	Homo sapiens (human)
Defective CUBN causes MGA1	Cobalamin binding intrinsic factor Cubilin Protein amnionless	O60494 P27352 Q9BXJ7	AMN CBLIF CUBN GIF IFCR IFMH	Homo sapiens (human)
HDL clearance	Apolipoprotein A-I Cubilin Protein amnionless Vigilin	O60494 P02647 Q00341 Q9BXJ7	AMN APOA1 CUBN HBP HDLBP IFCR VGL	Homo sapiens (human)
RUNX3 regulates YAP1-mediated transcription	CCN family member 2 Runt-related transcription factor 3 Transcriptional coactivator YAP1 Transcriptional enhancer factor TEF-1 Transcriptional enhancer factor TEF-3 Transcriptional enhancer factor TEF-4 Transcriptional enhancer factor TEF-5 WW domain-containing transcription regulator protein 1	P28347 P29279 P46937 Q13761 Q15561 Q15562 Q99594 Q9GZV5	AML2 CBFA3 CCN2 CTGF HCS24 IGFBP8 PEBP2A3 RTEF1 RUNX3 TAZ TCF13 TCF13L1 TEAD1 TEAD2 TEAD3 TEAD4 TEAD5 TEF1 TEF3 TEF4 TEF5 WWTR1 YAP1 YAP65	Homo sapiens (human)
RUNX3 regulates RUNX1-mediated transcription	Core-binding factor subunit beta Runt-related transcription factor 3	Q13761 Q13951	AML2 CBFA3 CBFB PEBP2A3 RUNX3	Homo sapiens (human)
RUNX3 Regulates Immune Response and Cell Migration	Core-binding factor subunit beta Integrin alpha-4 Integrin alpha-L Osteopontin Runt-related transcription factor 3	P10451 P13612 P20701 Q13761 Q13951	AML2 BNSP CBFA3 CBFB CD11A CD49D ITGA4 ITGAL OPN PEBP2A3 RUNX3 SPP1	Homo sapiens (human)
RUNX3 regulates NOTCH signaling	CREB-binding protein Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase p300 Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Neurogenic locus notch homolog protein 1 Protein jagged-1 Recombining binding protein suppressor of hairless Runt-related transcription factor 3 SNW domain-containing protein 1 Transcription factor HES-1	P46531 P78504 Q06330 Q09472 Q13495 Q13573 Q13761 Q14469 Q8IZL2 Q92585 Q92793 Q92830 Q92831 Q96JK9	AML2 BHLHB39 CBFA3 CBP CG1 CREBBP CXorf6 EP300 GCN5 GCN5L2 HES1 HL HRY IGKJRB IGKJRB1 JAG1 JAGL1 KAT2A KAT2B KIAA0200 KIAA1816 KIAA1819 MAML1 MAML2 MAML3 MAMLD1 NOTCH1 P300 PCAF PEBP2A3 RBPJ RBPJK RBPSUH RUNX3 SKIIP SKIP SNW1 TAN1	Homo sapiens (human)
RUNX3 regulates BCL2L11 (BIM) transcription	Bcl-2-like protein 11 Forkhead box protein O3 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Runt-related transcription factor 3	O43521 O43524 P84022 Q13485 Q13761	AML2 BCL2L11 BIM CBFA3 DPC4 FKHRL1 FOXO3 FOXO3A MADH3 MADH4 PEBP2A3 RUNX3 SMAD3 SMAD4	Homo sapiens (human)
RUNX3 regulates WNT signaling	Catenin beta-1 G1/S-specific cyclin-D1 Lymphoid enhancer-binding factor 1 Myc proto-oncogene protein Runt-related transcription factor 3 Transcription factor 7-like 1 Transcription factor 7-like 2 Transcription factor 7	P01106 P24385 P35222 P36402 Q13761 Q9HCS4 Q9NQB0 Q9UJU2	AML2 BCL1 BHLHE39 CBFA3 CCND1 CTNNB CTNNB1 LEF1 MYC PEBP2A3 PRAD1 RUNX3 TCF1 TCF3 TCF4 TCF7 TCF7L1 TCF7L2	Homo sapiens (human)
Binding of TCF/LEF:CTNNB1 to target gene promoters	Axin-2 Catenin beta-1 Lymphoid enhancer-binding factor 1 Myc proto-oncogene protein Runt-related transcription factor 3 Transcription factor 7-like 1 Transcription factor 7-like 2 Transcription factor 7	P01106 P35222 P36402 Q13761 Q9HCS4 Q9NQB0 Q9UJU2 Q9Y2T1	AML2 AXIN2 BHLHE39 CBFA3 CTNNB CTNNB1 LEF1 MYC PEBP2A3 RUNX3 TCF1 TCF3 TCF4 TCF7 TCF7L1 TCF7L2	Homo sapiens (human)
RUNX3 regulates CDKN1A transcription	Cellular tumor antigen p53 Cyclin-dependent kinase inhibitor 1 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Runt-related transcription factor 3 Transforming growth factor beta-1 proprotein Zinc finger homeobox protein 3	P01137 P04637 P38936 P84022 Q13485 Q13761 Q15911	AML2 ATBF1 C16orf47 CAP20 CBFA3 CDKN1 CDKN1A CIP1 DPC4 MADH3 MADH4 MDA6 P53 PEBP2A3 PIC1 RUNX3 SDI1 SMAD3 SMAD4 TGFB TGFB1 TP53 WAF1 ZFHX3	Homo sapiens (human)
RUNX2 regulates genes involved in differentiation of myeloid cells	Core-binding factor subunit beta Galectin-3 Runt-related transcription factor 1	P17931 Q01196 Q13951	AML1 CBFA2 CBFB LGALS3 MAC2 RUNX1	Homo sapiens (human)
RUNX1 regulates transcription of genes involved in interleukin signaling	Core-binding factor subunit beta ETS-related transcription factor Elf-1 Interleukin-3 Leukemia inhibitory factor receptor Runt-related transcription factor 1	P08700 P32519 P42702 Q01196 Q13951	AML1 CBFA2 CBFB ELF1 IL3 LIFR RUNX1	Homo sapiens (human)
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells	CREB-binding protein Core-binding factor subunit beta Galectin-3 Granulocyte-macrophage colony-stimulating factor Protein kinase C beta type Runt-related transcription factor 1	P04141 P05771 P17931 Q01196 Q13951 Q92793	AML1 CBFA2 CBFB CBP CREBBP CSF2 GMCSF LGALS3 MAC2 PKCB PRKCB PRKCB1 RUNX1	Homo sapiens (human)
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Cathepsin K Cathepsin L2 Core-binding factor subunit beta Procathepsin L Runt-related transcription factor 1 Serpin B13 Suppressor of cytokine signaling 3 Suppressor of cytokine signaling 4	O14543 O60911 P07711 P43235 Q01196 Q13951 Q8WXH5 Q9UIV8	AML1 CATL2 CBFA2 CBFB CIS3 CTSK CTSL CTSL1 CTSL2 CTSO CTSO2 CTSU CTSV PI13 RUNX1 SERPINB13 SOCS3 SOCS4 SOCS7 SSI3	Homo sapiens (human)
Organic cation transport	Organic cation/carnitine transporter 2 Regulatory solute carrier protein family 1 member 1 Runt-related transcription factor 1 Solute carrier family 22 member 15 Solute carrier family 22 member 16 Solute carrier family 22 member 18 Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 22 member 3 Solute carrier family 22 member 4	O15244 O15245 O75751 O76082 Q01196 Q86VW1 Q8IZD6 Q92681 Q96BI1 Q9H015	AML1 BWR1A BWSCR1A CBFA2 EMTH ETT FLIPT1 HET IMPT1 ITM OCT1 OCT2 OCT3 OCT6 OCTN1 OCTN2 ORCTL2 RSC1A1 RUNX1 SLC22A1 SLC22A15 SLC22A16 SLC22A18 SLC22A1L SLC22A2 SLC22A3 SLC22A4 SLC22A5 TSSC5 UT2H	Homo sapiens (human)

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