GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1576 - 1600** of **2074** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
RUNX1 regulates transcription of genes involved in interleukin signaling	Core-binding factor subunit beta ETS-related transcription factor Elf-1 Interleukin-3 Leukemia inhibitory factor receptor Runt-related transcription factor 1	P08700 P32519 P42702 Q01196 Q13951	AML1 CBFA2 CBFB ELF1 IL3 LIFR RUNX1	Homo sapiens (human)
SARS-CoV-1 modulates host translation machinery	Elongation factor 1-alpha 1 Heterogeneous nuclear ribonucleoprotein A1 Nucleoprotein Replicase polyprotein 1a Replicase polyprotein 1ab Ribosomal protein eS27-like Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P08708 P08865 P09651 P0C6U8 P0C6X7 P15880 P22090 P23396 P25398 P39019 P42677 P46781 P46782 P46783 P59595 P60866 P61247 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62701 P62753 P62841 P62847 P62851 P62854 P62857 P62861 P62979 P63220 P68104 Q71UM5 Q8TD47	1a CCG2 D6S218E EEF1A EEF1A1 EF1A FAU FTE1 HNRNPA1 HNRPA1 LAMBR LAMR1 LENG7 MFTL MPS1 N RIG RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA SCAR UBA80 UBCEP1 rep	Homo sapiens (human)
The activation of arylsulfatases	Arylsulfatase A Arylsulfatase B Arylsulfatase D Arylsulfatase F Arylsulfatase G Arylsulfatase H Arylsulfatase I Arylsulfatase J Arylsulfatase K Arylsulfatase L Formylglycine-generating enzyme Inactive C-alpha-formylglycine-generating enzyme 2 Steryl-sulfatase	P08842 P15289 P15848 P51689 P51690 P54793 Q5FYA8 Q5FYB0 Q5FYB1 Q6UWY0 Q8NBJ7 Q8NBK3 Q96EG1	ARSA ARSB ARSC1 ARSD ARSE ARSF ARSG ARSH ARSI ARSJ ARSK ARSL KIAA1001 STS SUMF1 SUMF2 TSULF	Homo sapiens (human)
Metabolism of steroid hormones	Steryl-sulfatase	P08842	ARSC1 STS	Homo sapiens (human)
Serotonin receptors	5-hydroxytryptamine receptor 1A 5-hydroxytryptamine receptor 1B 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 1E 5-hydroxytryptamine receptor 1F 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B 5-hydroxytryptamine receptor 2C 5-hydroxytryptamine receptor 4 5-hydroxytryptamine receptor 5A 5-hydroxytryptamine receptor 6 5-hydroxytryptamine receptor 7	P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P47898 P50406 Q13639	ADRB2RL1 ADRBRL1 HTR1A HTR1B HTR1C HTR1D HTR1DA HTR1DB HTR1E HTR1EL HTR1F HTR2 HTR2A HTR2B HTR2C HTR4 HTR5A HTR6 HTR7 HTRL	Homo sapiens (human)
Adrenaline signalling through Alpha-2 adrenergic receptor	Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor	P08913 P18089 P18825	ADRA2A ADRA2B ADRA2C ADRA2L1 ADRA2L2 ADRA2R ADRA2RL1 ADRA2RL2 ADRAR	Homo sapiens (human)
Formation of intermediate mesoderm	Bone morphogenetic protein 4 Fibroblast growth factor 2 Forkhead box protein C1 Forkhead box protein C2 LIM/homeobox protein Lhx1 Paired box protein Pax-2 Paired box protein Pax-8 Protein odd-skipped-related 1	P09038 P12644 P48742 Q02962 Q06710 Q12948 Q8TAX0 Q99958	BMP2B BMP4 DVR4 FGF2 FGFB FKHL14 FKHL7 FOXC1 FOXC2 FREAC3 LHX1 LIM-1 LIM1 MFH1 ODD OSR1 PAX2 PAX8	Homo sapiens (human)
Gap junction degradation	AP-2 complex subunit mu Clathrin heavy chain 1 Clathrin heavy chain 2 Clathrin light chain A Clathrin light chain B Disabled homolog 2 Dynamin-1 Dynamin-2 Gap junction alpha-1 protein Unconventional myosin-VI	P09496 P09497 P17302 P50570 P53675 P98082 Q00610 Q05193 Q96CW1 Q9UM54	AP2M1 CLAPM1 CLH17 CLH22 CLTA CLTB CLTC CLTCL CLTCL1 CLTCL2 CLTD DAB2 DNM DNM1 DNM2 DOC2 DYN2 GJA1 GJAL KIAA0034 KIAA0109 KIAA0389 MYO6	Homo sapiens (human)
Formation of annular gap junctions	AP-2 complex subunit mu Clathrin heavy chain 1 Clathrin heavy chain 2 Clathrin light chain A Clathrin light chain B Disabled homolog 2 Dynamin-1 Dynamin-2 Gap junction alpha-1 protein	P09496 P09497 P17302 P50570 P53675 P98082 Q00610 Q05193 Q96CW1	AP2M1 CLAPM1 CLH17 CLH22 CLTA CLTB CLTC CLTCL CLTCL1 CLTCL2 CLTD DAB2 DNM DNM1 DNM2 DOC2 DYN2 GJA1 GJAL KIAA0034 KIAA0109	Homo sapiens (human)
H139Hfs13* PPM1K causes a mild variant of MSUD	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial Protein phosphatase Mn(2+)-dependent 1K	P09622 P11182 P12694 P21953 Q8N3J5	BCATE2 BCKDHA BCKDHB BCKDHE2 DBT DLD GCSL LAD PHE3 PP2CM PPM1K	Homo sapiens (human)
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial	P09622 P11182 P12694 P21953	BCATE2 BCKDHA BCKDHB BCKDHE2 DBT DLD GCSL LAD PHE3	Homo sapiens (human)
Loss-of-function mutations in DBT cause MSUD2	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial	P09622 P11182 P12694 P21953	BCATE2 BCKDHA BCKDHB BCKDHE2 DBT DLD GCSL LAD PHE3	Homo sapiens (human)
Loss-of-function mutations in DLD cause MSUD3/DLDD	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial	P09622 P11182 P12694 P21953	BCATE2 BCKDHA BCKDHB BCKDHE2 DBT DLD GCSL LAD PHE3	Homo sapiens (human)
Glycine degradation	2-oxoglutarate dehydrogenase complex component E1 Alpha-ketoglutarate dehydrogenase component 4 Aminomethyltransferase, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial Glycine cleavage system H protein, mitochondrial Glycine dehydrogenase (decarboxylating), mitochondrial	P09622 P23378 P23434 P36957 P48728 P82909 Q02218	AMT DLD DLST DLTS GCSH GCSL GCSP GCST GLDC KGD4 LAD MRPS36 OGDH PHE3	Homo sapiens (human)
Succinyl-CoA Biosynthesis	2-oxoglutarate dehydrogenase complex component E1 Alpha-ketoglutarate dehydrogenase component 4 Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial	P09622 P36957 P82909 Q02218	DLD DLST DLTS GCSL KGD4 LAD MRPS36 OGDH PHE3	Homo sapiens (human)
OADH complex synthesizes glutaryl-CoA from 2-OA	2-oxoadipate dehydrogenase complex component E1 Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial	P09622 P36957 Q96HY7	DHTKD1 DLD DLST DLTS GCSL KIAA1630 LAD PHE3	Homo sapiens (human)
Intestinal saccharidase deficiencies	Lactase/phlorizin hydrolase Sucrase-isomaltase, intestinal	P09848 P14410	LCT LPH SI	Homo sapiens (human)	G74621DY G96370VA
Polymerase switching on the C-strand of the telomere	Adrenocortical dysplasia protein homolog CST complex subunit CTC1 CST complex subunit STN1 CST complex subunit TEN1 Chromosome transmission fidelity protein 18 homolog Chromosome transmission fidelity protein 8 homolog DNA polymerase alpha catalytic subunit DNA polymerase alpha subunit B DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA primase large subunit DNA primase small subunit Proliferating cell nuclear antigen Protection of telomeres protein 1 Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Sister chromatid cohesion protein DCC1 TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	P09884 P0CG13 P12004 P28340 P35249 P35250 P35251 P40937 P40938 P49005 P49642 P49643 P54274 Q14181 Q15054 Q15554 Q2NKJ3 Q86WV5 Q8WVB6 Q96AP0 Q9BSI4 Q9BVC3 Q9H668 Q9HCU8 Q9NUX5 Q9NYB0	ACD C16orf41 C17orf106 C17orf68 CHTF18 CHTF8 CTC1 CTF18 CTF8 DCC1 DRIP5 DSCC1 KIAA0039 OBFC1 PCNA PIN2 PIP1 POLA POLA1 POLA2 POLD POLD1 POLD2 POLD3 POLD4 POLDS POT1 PRIM1 PRIM2 PRIM2A PTOP RAP1 RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 STN1 TEN1 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2	Homo sapiens (human)
Removal of the Flap Intermediate	DNA polymerase alpha catalytic subunit DNA polymerase alpha subunit B DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA primase large subunit DNA primase small subunit DNA replication ATP-dependent helicase/nuclease DNA2 Flap endonuclease 1 Proliferating cell nuclear antigen Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit	P09884 P12004 P15927 P27694 P28340 P35244 P39748 P49005 P49642 P49643 P51530 Q14181 Q15054 Q9HCU8	DNA2 DNA2L FEN1 KIAA0039 KIAA0083 PCNA POLA POLA1 POLA2 POLD POLD1 POLD2 POLD3 POLD4 POLDS PRIM1 PRIM2 PRIM2A RAD2 REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70	Homo sapiens (human)
Processive synthesis on the lagging strand	DNA ligase 1 DNA polymerase alpha catalytic subunit DNA polymerase alpha subunit B DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA primase large subunit DNA primase small subunit Proliferating cell nuclear antigen	P09884 P12004 P18858 P28340 P49005 P49642 P49643 Q14181 Q15054 Q9HCU8	KIAA0039 LIG1 PCNA POLA POLA1 POLA2 POLD POLD1 POLD2 POLD3 POLD4 POLDS PRIM1 PRIM2 PRIM2A	Homo sapiens (human)
Polymerase switching	DNA polymerase alpha catalytic subunit DNA polymerase alpha subunit B DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA primase large subunit DNA primase small subunit Proliferating cell nuclear antigen Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5	P09884 P12004 P28340 P35249 P35250 P35251 P40937 P40938 P49005 P49642 P49643 Q14181 Q15054 Q9HCU8	KIAA0039 PCNA POLA POLA1 POLA2 POLD POLD1 POLD2 POLD3 POLD4 POLDS PRIM1 PRIM2 PRIM2A RFC1 RFC140 RFC2 RFC3 RFC4 RFC5	Homo sapiens (human)
Telomere C-strand synthesis initiation	Adrenocortical dysplasia protein homolog CST complex subunit CTC1 CST complex subunit STN1 CST complex subunit TEN1 DNA polymerase alpha catalytic subunit DNA polymerase alpha subunit B DNA primase large subunit DNA primase small subunit Protection of telomeres protein 1 TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	P09884 P49642 P49643 P54274 Q14181 Q15554 Q2NKJ3 Q86WV5 Q96AP0 Q9BSI4 Q9H668 Q9NUX5 Q9NYB0	ACD C17orf106 C17orf68 CTC1 DRIP5 OBFC1 PIN2 PIP1 POLA POLA1 POLA2 POT1 PRIM1 PRIM2 PRIM2A PTOP RAP1 STN1 TEN1 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2	Homo sapiens (human)
DNA replication initiation	DNA polymerase alpha catalytic subunit DNA polymerase alpha subunit B DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 DNA primase large subunit DNA primase small subunit	P09884 P49642 P49643 P56282 Q07864 Q14181 Q9NR33 Q9NRF9	CHRAC17 DPE2 POLA POLA1 POLA2 POLE POLE1 POLE2 POLE3 POLE4 PRIM1 PRIM2 PRIM2A	Homo sapiens (human)
Synthesis of Leukotrienes (LT) and Eoxins (EX)	Arachidonate 5-lipoxygenase-activating protein Cytochrome P450 4A11 Cytochrome P450 4A22 Cytochrome P450 4B1 Cytochrome P450 4F11 Cytochrome P450 4F2 Cytochrome P450 4F3 Cytochrome P450 4F8 Dipeptidase 1 Dipeptidase 2 Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme Leukotriene A-4 hydrolase Leukotriene C4 synthase MAP kinase-activated protein kinase 2 Multidrug resistance-associated protein 1 Polyunsaturated fatty acid 5-lipoxygenase Polyunsaturated fatty acid lipoxygenase ALOX15 Prostaglandin reductase 1 Ultra-long-chain fatty acid omega-hydroxylase	P09917 P09960 P13584 P16050 P16444 P19440 P20292 P33527 P36269 P49137 P78329 P98187 Q02928 Q08477 Q14914 Q16873 Q5TCH4 Q6NT55 Q9H4A9 Q9HBI6	ABCC1 ALOX15 ALOX5 ALOX5AP CYP4A11 CYP4A2 CYP4A22 CYP4B1 CYP4F11 CYP4F2 CYP4F22 CYP4F3 CYP4F8 DPEP1 DPEP2 FLAP GGT GGT1 GGT5 GGTLA1 LOG15 LOG5 LTA4 LTA4H LTB4DH LTB4H LTC4S MAPKAPK2 MDP MRP MRP1 PTGR1 RDP	Homo sapiens (human)
Biosynthesis of E-series 18(S)-resolvins	15-hydroxyprostaglandin dehydrogenase [NAD(+)] Leukotriene A-4 hydrolase Polyunsaturated fatty acid 5-lipoxygenase Polyunsaturated fatty acid lipoxygenase ALOX15	P09917 P09960 P15428 P16050	ALOX15 ALOX5 HPGD LOG15 LOG5 LTA4 LTA4H PGDH1 SDR36C1	Homo sapiens (human)

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