GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1 - 25** of **2074** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism
Defective VWF binding to collagen type I	von Willebrand factor	P04275	F8VWF VWF	Homo sapiens (human)
PKA-mediated phosphorylation of CREB	cAMP-dependent protein kinase catalytic subunit PRKX cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	P17612 P22612 P22694 P51817	PKACA PKX1 PRKACA PRKACB PRKACG PRKX	Homo sapiens (human)
Defective SLC39A4 causes acrodermatitis enteropathica, zinc-deficiency type (AEZ)	Zinc transporter ZIP4	Q6P5W5	SLC39A4 ZIP4	Homo sapiens (human)
ZBP1(DAI) mediated induction of type I IFNs	Z-DNA-binding protein 1	Q9H171	C20orf183 DLM1 ZBP1	Homo sapiens (human)
Defective SLC17A8 causes autosomal dominant deafness 25 (DFNA25)	Vesicular glutamate transporter 3	Q8NDX2	SLC17A8 VGLUT3	Homo sapiens (human)
Defective AVP does not bind AVPR2 and causes neurohypophyseal diabetes insipidus (NDI)	Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin	P01185 P30518	ADHR ARVP AVP AVPR2 DIR DIR3 V2R VP	Homo sapiens (human)
Defective AVP does not bind AVPR1A,B and causes neurohypophyseal diabetes insipidus (NDI)	Vasopressin V1a receptor Vasopressin V1b receptor Vasopressin-neurophysin 2-copeptin	P01185 P37288 P47901	ARVP AVP AVPR1 AVPR1A AVPR1B AVPR3 VP VPR3	Homo sapiens (human)
Ion channel transport	V-type proton ATPase 116 kDa subunit a 1 V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 116 kDa subunit a 3 V-type proton ATPase 116 kDa subunit a 4 V-type proton ATPase 16 kDa proteolipid subunit c V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase subunit B, brain isoform V-type proton ATPase subunit B, kidney isoform V-type proton ATPase subunit C 1 V-type proton ATPase subunit C 2 V-type proton ATPase subunit D V-type proton ATPase subunit E 1 V-type proton ATPase subunit E 2 V-type proton ATPase subunit F V-type proton ATPase subunit G 1 V-type proton ATPase subunit G 2 V-type proton ATPase subunit G 3 V-type proton ATPase subunit H V-type proton ATPase subunit S1 V-type proton ATPase subunit d 1 V-type proton ATPase subunit d 2 V-type proton ATPase subunit e 1 V-type proton ATPase subunit e 2	O15342 O75348 O95670 P15313 P21281 P21283 P27449 P36543 P38606 P61421 Q13488 Q15904 Q16864 Q8N8Y2 Q8NEY4 Q8NHE4 Q93050 Q96A05 Q96LB4 Q99437 Q9HBG4 Q9UI12 Q9Y487 Q9Y5K8	ATP6A1 ATP6AP1 ATP6B1 ATP6B2 ATP6C ATP6D ATP6E ATP6E1 ATP6E2 ATP6EL2 ATP6F ATP6G ATP6G1 ATP6G2 ATP6G3 ATP6H ATP6IP1 ATP6J ATP6L ATP6M ATP6N1 ATP6N1A ATP6N1B ATP6N1C ATP6N2 ATP6S1 ATP6S14 ATP6V0A1 ATP6V0A2 ATP6V0A3 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E ATP6V0E1 ATP6V0E2 ATP6V0E2L ATP6V1A ATP6V1A1 ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1D ATP6V1E1 ATP6V1E2 ATP6V1EL2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 ATP6V1H ATPL C7orf32 NG38 TCIRG1 VATB VATC VATD VATF VATPS1 VPATPD VPP1 VPP2 VPP3 XAP3	Homo sapiens (human)
Defective UGT1A4 causes hyperbilirubinemia	UDP-glucuronosyltransferase 1A4	P22310	GNT1 UGT1 UGT1A4	Homo sapiens (human)
Defective UGT1A1 causes hyperbilirubinemia	UDP-glucuronosyltransferase 1A1	P22309	GNT1 UGT1 UGT1A1	Homo sapiens (human)
Glycosaminoglycan metabolism	UDP-glucuronic acid decarboxylase 1	Q8NBZ7	UXS1	Homo sapiens (human)
Defective DPAGT1 causes CDG-1j, CMSTA2	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Q9H3H5	DPAGT1 DPAGT2	Homo sapiens (human)
Defective ALG14 causes ALG14-CMS	UDP-N-acetylglucosamine transferase subunit ALG13 UDP-N-acetylglucosamine transferase subunit ALG14	Q96F25 Q9NP73	ALG13 ALG14 CXorf45 GLT28D1	Homo sapiens (human)
PI Metabolism	Tumor necrosis factor alpha-induced protein 8-like protein 1 Tumor necrosis factor alpha-induced protein 8-like protein 2 Tumor necrosis factor alpha-induced protein 8-like protein 3 Tumor necrosis factor alpha-induced protein 8	O95379 Q5GJ75 Q6P589 Q8WVP5	TIPE3 TNFAIP8 TNFAIP8L1 TNFAIP8L2 TNFAIP8L3	Homo sapiens (human)
Beta oxidation of palmitoyl-CoA to myristoyl-CoA	Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	P40939 P49748 P55084	ACADVL HADH HADHA HADHB VLCAD	Homo sapiens (human)
GLI proteins bind promoters of Hh responsive genes to promote transcription	Transcriptional activator GLI3 Zinc finger protein GLI1 Zinc finger protein GLI2	P08151 P10070 P10071	GLI GLI1 GLI2 GLI3 THP	Homo sapiens (human)
Insulin effects increased synthesis of Xylulose-5-Phosphate	Transaldolase Transketolase	P29401 P37837	TAL TALDO TALDO1 TALDOR TKT	Homo sapiens (human)
Defective regulation of TLR7 by endogenous ligand	Toll-like receptor 7	Q9NYK1	TLR7	Homo sapiens (human)
Toll Like Receptor 7/8 (TLR7/8) Cascade	Toll-like receptor 7 Toll-like receptor 8	Q9NR97 Q9NYK1	TLR7 TLR8	Homo sapiens (human)
TLR3 deficiency - HSE	Toll-like receptor 3	O15455	TLR3	Homo sapiens (human)
Toll Like Receptor 10 (TLR10) Cascade	Toll-like receptor 10	Q9BXR5	TLR10	Homo sapiens (human)
TICAM1 deficiency - HSE	TIR domain-containing adapter molecule 1 Toll-like receptor 3	O15455 Q8IUC6	PRVTIRB TICAM1 TLR3 TRIF	Homo sapiens (human)
Toll Like Receptor 3 (TLR3) Cascade	TIR domain-containing adapter molecule 1 Toll-like receptor 3	O15455 Q8IUC6	PRVTIRB TICAM1 TLR3 TRIF	Homo sapiens (human)
TRAF3 deficiency - HSE	TIR domain-containing adapter molecule 1 TNF receptor-associated factor 3 Toll-like receptor 3	O15455 Q13114 Q8IUC6	CAP-1 CRAF1 PRVTIRB TICAM1 TLR3 TRAF3 TRAFAMN TRIF	Homo sapiens (human)
TGFBR2 MSI Frameshift Mutants in Cancer	TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein	P01137 P37173	TGFB TGFB1 TGFBR2	Homo sapiens (human)

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