Parkinson's disease

Summary
Synonym
  • Parkinson disease
  • paralysis agitans
Definition
A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.
Super Class
synucleinopathy
Related Genes
Displaying entries 1 - 10 of 180 in total
Gene ID Gene Symbol Description Source
2 A2M alpha-2-macroglobulin
25 ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
43 ACHE acetylcholinesterase (Yt blood group)
50 ACO2 aconitase 2
111 ADCY5 adenylate cyclase 5
131 ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
142 PARP1 poly(ADP-ribose) polymerase 1
157 GRK3 G protein-coupled receptor kinase 3
185 AGTR1 angiotensin II receptor type 1
207 AKT1 AKT serine/threonine kinase 1
Displaying entries 71 - 80 of 146 in total
Gene ID Gene Symbol Description Source
19276 Ptprn2 protein tyrosine phosphatase receptor type N polypeptide 2
20317 Serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1
20333 Sec22b SEC22 homolog B, vesicle trafficking protein
20605 Sstr1 somatostatin receptor 1
20606 Sstr2 somatostatin receptor 2
20607 Sstr3 somatostatin receptor 3
20608 Sstr4 somatostatin receptor 4
20609 Sstr5 somatostatin receptor 5
20617 Snca synuclein, alpha
20618 Sncg synuclein, gamma
Displaying entries 51 - 60 of 82 in total
Gene ID Gene Symbol Description Source
81646 Creb1 cAMP responsive element binding protein 1
81728 Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2
83516 Ppargc1a PPARG coactivator 1 alpha
83529 Vdac1 voltage-dependent anion channel 1
83567 Mchr1 melanin-concentrating hormone receptor 1
83613 Nefl neurofilament light chain
83817 Ache acetylcholinesterase
84027 Gsk3b glycogen synthase kinase 3 beta
84487 Slc17a6 solute carrier family 17 member 6
85238 Synj1 synaptojanin 1
Displaying entries 1 - 10 of 25 in total
Gene ID Gene Symbol Description Source
31248 sgg shaggy
31399 Torsin torsin
31718 Tbh Tyramine beta hydroxylase
31806 Ogg1 8-oxoguanine DNA glycosylase
33007 Dop2R Dopamine 2-like receptor
33461 Pgk Phosphoglycerate kinase
35851 ptc patched
35886 Pgi Phosphoglucose isomerase
36232 Sod3 Superoxide dismutase 3
37191 5-HT1B 5-hydroxytryptamine (serotonin) receptor 1B
Displaying all 9 entries
Gene ID Gene Symbol Description Source
114549 ache acetylcholinesterase (Yt blood group)
436629 nus1 NUS1 dehydrodolichyl diphosphate synthase subunit
437021 tspan36 tetraspanin 36
494492 slc17a6a solute carrier family 17 member 6a
560788 parp1 poly (ADP-ribose) polymerase 1
563467 slc17a8 solute carrier family 17 member 8
768121 foxo1a forkhead box O1 a
100004455 epoa erythropoietin a
100149756 slc17a6b solute carrier family 17 member 6b
Displaying all 7 entries
Gene ID Gene Symbol Description Source Organism
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
398763 agtr1.L angiotensin II receptor type 1 L homeolog Xenopus laevis (African clawed frog)
399170 akt1.S AKT serine/threonine kinase 1 S homeolog Xenopus laevis (African clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
108705891 drd5.S dopamine receptor D5 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 26 in total
Gene ID Gene Symbol Description Source
171965 pgk-1 putative phosphoglycerate kinase
172105 unc-38 Acetylcholine receptor subunit alpha-type unc-38
172150 unc-63 Acetylcholine receptor subunit alpha-type unc-63
173574 gba-1 Putative glucosylceramidase 1
174274 ptc-1 Protein patched homolog 1;SSD domain-containing protein
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175076 ace-3 Carboxylic ester hydrolase
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176291 eat-4 Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4
Displaying entries 11 - 19 of 19 in total
Gene ID Gene Symbol Description Source
853313 PBS2 mitogen-activated protein kinase kinase PBS2
853734 RRN3 rDNA-binding RNA polymerase I transcriptional factor
854276 INP53 phosphatidylinositol-3-/phosphoinositide 5-phosphatase INP53
854713 PRK1 serine/threonine protein kinase PRK1
854900 HMG1 hydroxymethylglutaryl-CoA reductase (NADPH) HMG1
854942 OGG1 8-oxoguanine glycosylase OGG1
855552 PSD1 phosphatidylserine decarboxylase 1
855711 ARK1 serine/threonine protein kinase ARK1
855999 SYH1 Syh1p

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Last updated: December 9, 2024