cystic fibrosis

Summary
Synonym
  • CF
  • mucoviscidosis
Definition
A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.
Super Class
autosomal recessive disease syndrome
Disease Ontology
DOID:1485
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
OMIM
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 72 in total
Gene ID Gene Symbol Description Source
12 SERPINA3 serpin family A member 3
153 ADRB1 adrenoceptor beta 1
154 ADRB2 adrenoceptor beta 2
155 ADRB3 adrenoceptor beta 3
177 AGER advanced glycosylation end-product specific receptor
355 FAS Fas cell surface death receptor
356 FASLG Fas ligand
727 C5 complement C5
929 CD14 CD14 molecule
959 CD40LG CD40 ligand
Displaying entries 61 - 70 of 78 in total
Gene ID Gene Symbol Description Source
21857 Timp1 tissue inhibitor of metalloproteinase 1
21898 Tlr4 toll-like receptor 4
21926 Tnf tumor necrosis factor
21947 Cd40lg CD40 ligand
23844 Clca1 chloride channel accessory 1
27413 Abcb11 ATP-binding cassette, sub-family B member 11
53791 Tlr5 toll-like receptor 5
74069 Serpina3a serine (or cysteine) peptidase inhibitor, clade A, member 3A
74180 Muc5b mucin 5, subtype B, tracheobronchial
77706 Abcb5 ATP-binding cassette, sub-family B member 5
Displaying entries 1 - 10 of 43 in total
Gene ID Gene Symbol Description Source
24255 Cftr CF transmembrane conductance regulator
24296 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
24484 Igfbp3 insulin-like growth factor binding protein 3
24493 Il1a interleukin 1 alpha
24598 Nos1 nitric oxide synthase 1
24600 Nos3 nitric oxide synthase 3
24767 Scnn1b sodium channel epithelial 1 subunit beta
24770 Ccl2 C-C motif chemokine ligand 2
24773 Sftpa1 surfactant protein A1
24794 Serpina3c serine (or cysteine) proteinase inhibitor, clade A, member 3C
Displaying all 9 entries
Gene ID Gene Symbol Description Source
34091 Spn28Dc Serpin 28Dc
34714 Edem2 ER degradation enhancer, mannosidase alpha-like 2
36428 Mdr49 Multi drug resistance 49
38326 Pxn Peroxidasin
38726 Mdr65 Multi drug resistance 65
41549 Octbeta2R Octopamine beta2 receptor
42652 Octbeta1R Octopamine beta1 receptor
43222 Tl Toll
47905 l(2)03659 lethal (2) 03659
Displaying all 3 entries
Gene ID Gene Symbol Description Source
403139 tlr5b toll-like receptor 5b
559080 cftr CF transmembrane conductance regulator
791973 cxcr3.2 chemokine (C-X-C motif) receptor 3, tandem duplicate 2
Displaying all 2 entries
Gene ID Gene Symbol Description Source Organism
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
108697308 adrb1.L adrenoceptor beta 1 L homeolog Xenopus laevis (African clawed frog)
Displaying entry 11 - 11 of 11 in total
Gene ID Gene Symbol Description Source
191484 pxn-1 Peroxidasin homolog pxn-1
Displaying all 4 entries
Gene ID Gene Symbol Description Source
853198 YOR1 ATP-binding cassette transporter YOR1
853671 STE6 ATP-binding cassette a-factor transporter STE6
853978 NFT1 putative multidrug transporter NFT1
856611 MNL1 alpha-1,2-mannosidase MNL1
The Human Phenotype Ontology
Displaying entries 11 - 20 of 32 in total
HPO ID HPO Term
HP:0003251 Male infertility
HP:0001508 Failure to thrive
HP:0012236 Elevated sweat chloride
HP:0002035 Rectal prolapse
HP:0000938 Osteopenia
HP:0002726 Recurrent Staphylococcus aureus infections
HP:0000246 Sinusitis
HP:0002107 Pneumothorax
HP:0002910 Elevated circulating hepatic transaminase concentration
HP:0001394 Cirrhosis
Displaying 1 entry
Gene ID Gene Symbol Description
4680 CEACAM6 CEA cell adhesion molecule 6

About Release Notes Help Feedback

Click here to visit the beta site.


International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International


GlyCosmos Portal v4.1.0

Last updated: December 9, 2024