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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
amyotrophic lateral sclerosis
Summary
- Synonym
-
- ALS
- Lou Gehrig's disease
- motor neuron disease, bulbar
- Definition
- A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.
- Super Class
- motor neuron disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 9217 | VAPB | VAMP associated protein B and C | |
| 9218 | VAPA | VAMP associated protein A | |
| 9759 | HDAC4 | histone deacetylase 4 | |
| 9817 | KEAP1 | kelch like ECH associated protein 1 | |
| 10133 | OPTN | optineurin | |
| 10891 | PPARGC1A | PPARG coactivator 1 alpha | |
| 23025 | UNC13A | unc-13 homolog A | |
| 23095 | KIF1B | kinesin family member 1B | |
| 23098 | SARM1 | sterile alpha and TIR motif containing 1 | |
| 23400 | ATP13A2 | ATPase cation transporting 13A2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 14824 | Grn | granulin | |
| 15289 | Hmgb1 | high mobility group box 1 | |
| 16001 | Igf1r | insulin-like growth factor I receptor | |
| 16004 | Igf2r | insulin-like growth factor 2 receptor | |
| 16427 | Itih4 | inter alpha-trypsin inhibitor, heavy chain 4 | |
| 16542 | Kdr | kinase insert domain protein receptor | |
| 16819 | Lcn2 | lipocalin 2 | |
| 17390 | Mmp2 | matrix metallopeptidase 2 | |
| 17395 | Mmp9 | matrix metallopeptidase 9 | |
| 17700 | Mstn | myostatin |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 25715 | Slc11a2 | solute carrier family 11 member 2 | |
| 25718 | Igf1r | insulin-like growth factor 1 receptor | |
| 29143 | Grn | granulin precursor | |
| 29152 | Mstn | myostatin | |
| 29167 | Dctn1 | dynactin subunit 1 | |
| 29272 | Dpp6 | dipeptidyl peptidase like 6 | |
| 29482 | Slc1a2 | solute carrier family 1 member 2 | |
| 29527 | Ptgs2 | prostaglandin-endoperoxide synthase 2 | |
| 50686 | Gsk3a | glycogen synthase kinase 3 alpha | |
| 81686 | Mmp2 | matrix metallopeptidase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31248 | sgg | shaggy | |
| 36232 | Sod3 | Superoxide dismutase 3 | |
| 38657 | vn | vein | |
| 38895 | Sarm | Sterile alpha and Armadillo motif | |
| 42490 | Mvl | Malvolio | |
| 42549 | InR | Insulin-like receptor | |
| 43223 | Lerp | lysosomal enzyme receptor protein | |
| 43469 | Ptp99A | Protein tyrosine phosphatase 99A | |
| 44811 | E(bx) | Enhancer of bithorax |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30682 | vegfaa | vascular endothelial growth factor Aa | |
| 403143 | sarm1 | sterile alpha and TIR motif containing 1 | |
| 447803 | pon1 | paraoxonase 1 | |
| 554230 | kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) | |
| 798441 | mstnb | myostatin b | |
| 100004455 | epoa | erythropoietin a |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 380341 | pon2.L | paraoxonase 2 L homeolog | Xenopus laevis (African clawed frog) | |
| 432039 | pon2.S | paraoxonase 2 S homeolog | Xenopus laevis (African clawed frog) | |
| 448598 | pon2 | paraoxonase 2 | Xenopus tropicalis (tropical clawed frog) | |
| 779087 | gdnf.L | glial cell derived neurotrophic factor L homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 175182 | ver-1 | Protein ver-1 | |
| 175237 | daf-7 | Dauer larva development regulatory growth factor daf-7 | |
| 175410 | daf-2 | Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase | |
| 175502 | tir-1 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein 1 | |
| 177044 | smf-3 | NRAMP-like transporter smf-3 | |
| 177343 | skn-1 | BZIP domain-containing protein;Protein skinhead-1 | |
| 177882 | glt-3 | Putative sodium-dependent excitatory amino acid transporter glt-3 | |
| 178748 | zmp-3 | Matrix metalloproteinase-C | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180042 | dpf-1 | Dipeptidyl peptidase family member 1 |
