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Standards Ontologies Notations
colorectal cancer

Summary
Definition
A large intestine cancer that is located_in the colon and/or located_in the rectum.
Super Class
large intestine cancer
Disease Ontology
DOID:9256
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 91 - 100 of 174 in total
Gene ID Gene Symbol Description Source
5320 PLA2G2A phospholipase A2 group IIA
5335 PLCG1 phospholipase C gamma 1
5424 POLD1 DNA polymerase delta 1, catalytic subunit
5426 POLE DNA polymerase epsilon, catalytic subunit
5601 MAPK9 mitogen-activated protein kinase 9
5728 PTEN phosphatase and tensin homolog
5782 PTPN12 protein tyrosine phosphatase non-receptor type 12
5783 PTPN13 protein tyrosine phosphatase non-receptor type 13
5795 PTPRJ protein tyrosine phosphatase receptor type J
5861 RAB1A RAB1A, member RAS oncogene family
Displaying entries 81 - 90 of 125 in total
Gene ID Gene Symbol Description Source
21825 Thbs1 thrombospondin 1
21929 Tnfaip3 tumor necrosis factor, alpha-induced protein 3
21950 Tnfsf9 tumor necrosis factor (ligand) superfamily, member 9
22059 Trp53 transformation related protein 53
22139 Ttr transthyretin
22289 Kdm6a lysine (K)-specific demethylase 6A
22339 Vegfa vascular endothelial growth factor A
22601 Yap1 yes-associated protein 1
22612 Yes1 YES proto-oncogene 1, Src family tyrosine kinase
24088 Tlr2 toll-like receptor 2
Displaying entries 11 - 20 of 44 in total
Gene ID Gene Symbol Description Source
25283 Gclc glutamate-cysteine ligase, catalytic subunit
25311 Dcc DCC netrin 1 receptor
25496 Notch1 notch receptor 1
25513 Pik3r1 phosphoinositide-3-kinase regulatory subunit 1
25589 Kdr kinase insert domain receptor
25717 Tgfb3 transforming growth factor, beta 3
29199 Hfe homeostatic iron regulator
29499 Shh sonic hedgehog signaling molecule
29591 Tgfbr1 transforming growth factor, beta receptor 1
29613 Ntrk3 neurotrophic receptor tyrosine kinase 3
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
31293 N Notch
31792 Nrg Neuroglian
32556 Stim Stromal interaction molecule
33196 smo smoothened
33496 lilli lilliputian
34091 Spn28Dc Serpin 28Dc
35560 Bap170 Brahma associated protein 170kD
37455 Egfr Epidermal growth factor receptor
39392 Est-6 Esterase 6
39393 Est-P Esterase P
Displaying all 8 entries
Gene ID Gene Symbol Description Source
30225 smo smoothened, frizzled class receptor
30682 vegfaa vascular endothelial growth factor Aa
30718 notch1a notch receptor 1a
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
559736 galnt12 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12
100006041 rhoab ras homolog gene family, member Ab
Displaying entries 1 - 10 of 16 in total
Gene ID Gene Symbol Description Source Organism
373801 tgfb2.L transforming growth factor beta 2 L homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380373 cxcr4.S C-X-C motif chemokine receptor 4 S homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
397787 ttr.L transthyretin L homeolog Xenopus laevis (African clawed frog)
399170 akt1.S AKT serine/threonine kinase 1 S homeolog Xenopus laevis (African clawed frog)
399187 adam10.S ADAM metallopeptidase domain 10 S homeolog Xenopus laevis (African clawed frog)
399347 fgfr3.S fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog Xenopus laevis (African clawed frog)
432172 akt2.S v-akt murine thymoma viral oncogene homolog 2 S homeolog Xenopus laevis (African clawed frog)
100037842 notch1 notch 1 receptor Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 27 in total
Gene ID Gene Symbol Description Source
172233 unc-40 Netrin receptor unc-40
172689 sup-17 Disintegrin and metalloproteinase domain-containing protein 10 homolog
174044 sma-6 Serine/threonine-protein kinase receptor sma-6
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175182 ver-1 Protein ver-1
175201 stim-1 Stromal interaction molecule 1
175590 cdh-4 Cadherin-4
176282 lin-12 lin-12/Notch intracellular domain
176286 glp-1 glp-1/Notch intracellular domain
176575 plr-1 putative E3 ubiquitin-protein ligase plr-1
Displaying entries 1 - 10 of 12 in total
Gene ID Gene Symbol Description Source
850438 ERS1 cystinosin-like protein ERS1
850614 HXK1 hexokinase 1
851543 OSH2 oxysterol-binding protein related protein OSH2
851670 GIS1 histone demethylase GIS1
852410 CYC8 transcription regulator CYC8
852546 GPX2 glutathione peroxidase GPX2
853313 PBS2 mitogen-activated protein kinase kinase PBS2
853361 ALY2 Aly2p
853770 BUD2 GTPase-activating protein BUD2
853842 GPX1 glutathione peroxidase GPX1
The Human Phenotype Ontology
Displaying all 7 entries
HPO ID HPO Term
HP:0000006 Autosomal dominant inheritance
HP:0006716 Hereditary nonpolyposis colorectal carcinoma
HP:0002891 Uterine leiomyosarcoma
HP:0006753 Neoplasm of the stomach
HP:0001442 Typified by somatic mosaicism
HP:0006740 Transitional cell carcinoma of the bladder
HP:0005584 Renal cell carcinoma
Displaying all 3 entries
Gene ID Gene Symbol Description
4893 NRAS NRAS proto-oncogene, GTPase
5290 PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5320 PLA2G2A phospholipase A2 group IIA
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024