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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
colorectal cancer
Summary
- Definition
- A large intestine cancer that is located_in the colon and/or located_in the rectum.
- Super Class
- large intestine cancer
External Links
- Disease Ontology
- DOID:9256
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 25 | ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | |
| 102 | ADAM10 | ADAM metallopeptidase domain 10 | |
| 133 | ADM | adrenomedullin | |
| 207 | AKT1 | AKT serine/threonine kinase 1 | |
| 208 | AKT2 | AKT serine/threonine kinase 2 | |
| 324 | APC | APC regulator of WNT signaling pathway | |
| 329 | BIRC2 | baculoviral IAP repeat containing 2 | |
| 331 | XIAP | X-linked inhibitor of apoptosis | |
| 345 | APOC3 | apolipoprotein C3 | |
| 387 | RHOA | ras homolog family member A |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 26398 | Map2k4 | mitogen-activated protein kinase kinase 4 | |
| 26921 | Map4k4 | mitogen-activated protein kinase kinase kinase kinase 4 | |
| 50768 | Dlc1 | deleted in liver cancer 1 | |
| 51810 | Hnrnpu | heterogeneous nuclear ribonucleoprotein U | |
| 53860 | Septin9 | septin 9 | |
| 54409 | Ramp2 | receptor (calcitonin) activity modifying protein 2 | |
| 56089 | Ramp3 | receptor (calcitonin) activity modifying protein 3 | |
| 67052 | Ndc80 | NDC80 kinetochore complex component | |
| 68010 | Bambi | BMP and activin membrane-bound inhibitor | |
| 68797 | Pdgfrl | platelet-derived growth factor receptor-like |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 81687 | Mmp9 | matrix metallopeptidase 9 | |
| 81809 | Tgfb2 | transforming growth factor, beta 2 | |
| 83619 | Nfe2l2 | NFE2 like bZIP transcription factor 2 | |
| 83785 | Vegfa | vascular endothelial growth factor A | |
| 83837 | Bambi | BMP and activin membrane-bound inhibitor | |
| 84353 | Ctnnb1 | catenin beta 1 | |
| 113902 | Ces1d | carboxylesterase 1D | |
| 170911 | Pik3ca | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | |
| 260320 | F7 | coagulation factor VII | |
| 290771 | Pdgfrl | platelet-derived growth factor receptor-like |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31293 | N | Notch | |
| 31792 | Nrg | Neuroglian | |
| 32556 | Stim | Stromal interaction molecule | |
| 33196 | smo | smoothened | |
| 33496 | lilli | lilliputian | |
| 34091 | Spn28Dc | Serpin 28Dc | |
| 35560 | Bap170 | Brahma associated protein 170kD | |
| 37455 | Egfr | Epidermal growth factor receptor | |
| 39392 | Est-6 | Esterase 6 | |
| 39393 | Est-P | Esterase P |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30225 | smo | smoothened, frizzled class receptor | |
| 30682 | vegfaa | vascular endothelial growth factor Aa | |
| 30718 | notch1a | notch receptor 1a | |
| 406411 | rhoaa | ras homolog gene family, member Aa | |
| 406659 | rhoac | ras homolog gene family, member Ac | |
| 554230 | kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) | |
| 559736 | galnt12 | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 | |
| 100006041 | rhoab | ras homolog gene family, member Ab |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 100038176 | cxcr4 | C-X-C motif chemokine receptor 4 | Xenopus tropicalis (tropical clawed frog) | |
| 100127346 | grin2a.L | glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog | Xenopus laevis (African clawed frog) | |
| 100192360 | cxcr4.L | C-X-C motif chemokine receptor 4 L homeolog | Xenopus laevis (African clawed frog) | |
| 100485011 | galnt12 | polypeptide N-acetylgalactosaminyltransferase 12 | Xenopus tropicalis (tropical clawed frog) | |
| 100491274 | rnf43 | ring finger protein 43 | Xenopus tropicalis (tropical clawed frog) | |
| 108719043 | galnt12.L | polypeptide N-acetylgalactosaminyltransferase 12 L homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 172233 | unc-40 | Netrin receptor unc-40 | |
| 172689 | sup-17 | Disintegrin and metalloproteinase domain-containing protein 10 homolog | |
| 174044 | sma-6 | Serine/threonine-protein kinase receptor sma-6 | |
| 174462 | let-23 | Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase | |
| 175182 | ver-1 | Protein ver-1 | |
| 175201 | stim-1 | Stromal interaction molecule 1 | |
| 175590 | cdh-4 | Cadherin-4 | |
| 176282 | lin-12 | lin-12/Notch intracellular domain | |
| 176286 | glp-1 | glp-1/Notch intracellular domain | |
| 176575 | plr-1 | putative E3 ubiquitin-protein ligase plr-1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850438 | ERS1 | cystinosin-like protein ERS1 | |
| 850614 | HXK1 | hexokinase 1 | |
| 851543 | OSH2 | oxysterol-binding protein related protein OSH2 | |
| 851670 | GIS1 | histone demethylase GIS1 | |
| 852410 | CYC8 | transcription regulator CYC8 | |
| 852546 | GPX2 | glutathione peroxidase GPX2 | |
| 853313 | PBS2 | mitogen-activated protein kinase kinase PBS2 | |
| 853361 | ALY2 | Aly2p | |
| 853770 | BUD2 | GTPase-activating protein BUD2 | |
| 853842 | GPX1 | glutathione peroxidase GPX1 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000006 | Autosomal dominant inheritance |
| HP:0006716 | Hereditary nonpolyposis colorectal carcinoma |
| HP:0002891 | Uterine leiomyosarcoma |
| HP:0006753 | Neoplasm of the stomach |
| HP:0001442 | Typified by somatic mosaicism |
| HP:0006740 | Transitional cell carcinoma of the bladder |
| HP:0005584 | Renal cell carcinoma |
