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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
diabetes mellitus
Summary
- Synonym
-
- diabetes
- Definition
- A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.
- Super Class
- glucose metabolism disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 654 | BMP6 | bone morphogenetic protein 6 | |
| 655 | BMP7 | bone morphogenetic protein 7 | |
| 656 | BMP8B | bone morphogenetic protein 8b | |
| 959 | CD40LG | CD40 ligand | |
| 999 | CDH1 | cadherin 1 | |
| 1080 | CFTR | CF transmembrane conductance regulator | |
| 1361 | CPB2 | carboxypeptidase B2 | |
| 1436 | CSF1R | colony stimulating factor 1 receptor | |
| 1508 | CTSB | cathepsin B | |
| 1543 | CYP1A1 | cytochrome P450 family 1 subfamily A member 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 23920 | Insrr | insulin receptor-related receptor | |
| 26357 | Abcg2 | ATP binding cassette subfamily G member 2 (Junior blood group) | |
| 54485 | Dll4 | delta like canonical Notch ligand 4 | |
| 56373 | Cpb2 | carboxypeptidase B2 | |
| 68916 | Cdkal1 | CDK5 regulatory subunit associated protein 1-like 1 | |
| 71665 | Fuca1 | fucosidase, alpha-L- 1, tissue | |
| 103988 | Gck | glucokinase | |
| 108155 | Ogt | O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) | |
| 116914 | Slc19a2 | solute carrier family 19 (thiamine transporter), member 2 | |
| 238055 | Apob | apolipoprotein B |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 25675 | Hmgcr | 3-hydroxy-3-methylglutaryl-CoA reductase | |
| 25704 | Il2ra | interleukin 2 receptor subunit alpha | |
| 25718 | Igf1r | insulin-like growth factor 1 receptor | |
| 25747 | Ppara | peroxisome proliferator activated receptor alpha | |
| 26295 | Ogt | O-linked N-acetylglucosamine (GlcNAc) transferase | |
| 29199 | Hfe | homeostatic iron regulator | |
| 29260 | Tlr4 | toll-like receptor 4 | |
| 29436 | Tfpi | tissue factor pathway inhibitor | |
| 29535 | Pdx1 | pancreatic and duodenal homeobox 1 | |
| 29714 | Ptprn2 | protein tyrosine phosphatase, receptor type N2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31234 | Pdfr | Pigment-dispersing factor receptor | |
| 31271 | w | white | |
| 32974 | Zw | Zwischenferment | |
| 34091 | Spn28Dc | Serpin 28Dc | |
| 35259 | Lar | Leukocyte-antigen-related-like | |
| 35486 | sxc | super sex combs | |
| 36692 | scb | scab | |
| 37455 | Egfr | Epidermal growth factor receptor | |
| 37778 | gbb | glass bottom boat | |
| 38109 | Glut1 | Glucose transporter 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30262 | ins | preproinsulin | |
| 64274 | csf1ra | colony stimulating factor 1 receptor, a | |
| 114424 | cdh1 | cadherin 1, type 1, E-cadherin (epithelial) | |
| 322857 | prom1a | prominin 1a | |
| 337685 | ogt.1 | O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1 | |
| 559080 | cftr | CF transmembrane conductance regulator |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 378695 | ins.L | insulin L homeolog | Xenopus laevis (African clawed frog) | |
| 378696 | ins.S | insulin S homeolog | Xenopus laevis (African clawed frog) | |
| 397750 | hmgcr.L | 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog | Xenopus laevis (African clawed frog) | |
| 397778 | tgfb1.L | transforming growth factor beta 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 398006 | insr.L | insulin receptor L homeolog | Xenopus laevis (African clawed frog) | |
| 398022 | igf1r.S | insulin like growth factor 1 receptor S homeolog | Xenopus laevis (African clawed frog) | |
| 553157 | ogt | O-linked N-acetylglucosamine (GlcNAc) transferase | Xenopus tropicalis (tropical clawed frog) | |
| 100337618 | cdh1.S | cadherin 1, type 1 S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 171619 | C53D5.5 | Gamma-glutamyltranspeptidase 1 | |
| 174462 | let-23 | Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase | |
| 174685 | ptp-3 | Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase | |
| 175410 | daf-2 | Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase | |
| 175807 | ida-1 | Receptor-type tyrosine-protein phosphatase-like ida-1 | |
| 176000 | ogt-1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase;protein O-GlcNAc transferase | |
| 178046 | gspd-1 | Glucose-6-phosphate 1-dehydrogenase | |
| 178748 | zmp-3 | Matrix metalloproteinase-C | |
| 179053 | cpr-4 | Cathepsin B-like cysteine proteinase 4 | |
| 179197 | cri-2 | Putative metalloproteinase inhibitor tag-225 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850317 | GLK1 | glucokinase | |
| 850369 | ADP1 | putative ATP-dependent permease ADP1 | |
| 850462 | GIT1 | Git1p | |
| 850614 | HXK1 | hexokinase 1 | |
| 851006 | ECM38 | gamma-glutamyltransferase | |
| 851171 | HMG2 | hydroxymethylglutaryl-CoA reductase (NADPH) HMG2 | |
| 852128 | EMI2 | putative glucokinase | |
| 852543 | VVS1 | Vvs1p | |
| 852639 | HXK2 | hexokinase 2 | |
| 853978 | NFT1 | putative multidrug transporter NFT1 |
