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Standards Ontologies Notations
type 2 diabetes mellitus

Summary
Synonym
  • NIDDM
  • insulin resistance
  • non-insulin-dependent diabetes mellitus
  • type 2 diabetes
  • type II diabetes mellitus
Definition
A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Super Class
diabetes mellitus
Disease Ontology
DOID:9352
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 261 - 270 of 325 in total
Gene ID Gene Symbol Description Source
7840 ALMS1 ALMS1 centrosome and basal body associated protein
7941 PLA2G7 phospholipase A2 group VII
8243 SMC1A structural maintenance of chromosomes 1A
8471 IRS4 insulin receptor substrate 4
8473 OGT O-linked N-acetylglucosamine (GlcNAc) transferase
8567 MADD MAP kinase activating death domain
8639 AOC3 amine oxidase copper containing 3
8660 IRS2 insulin receptor substrate 2
8665 EIF3F eukaryotic translation initiation factor 3 subunit F
8877 SPHK1 sphingosine kinase 1
Displaying entries 211 - 220 of 249 in total
Gene ID Gene Symbol Description Source
72508 Rps6kb1 ribosomal protein S6 kinase, polypeptide 1
74006 Dnm1l dynamin 1-like
74343 Crtc2 CREB regulated transcription coactivator 2
74769 Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
76055 Oga O-GlcNAcase
76282 Gpt glutamic pyruvic transaminase, soluble
83995 Mmp1a matrix metallopeptidase 1a (interstitial collagenase)
93686 Rbfox2 RNA binding protein, fox-1 homolog (C. elegans) 2
93736 Aff4 AF4/FMR2 family, member 4
94284 Ugt1a6a UDP glucuronosyltransferase 1 family, polypeptide A6A
Displaying entries 1 - 10 of 166 in total
Gene ID Gene Symbol Description Source
24152 Asip agouti signaling protein
24179 Agt angiotensinogen
24182 Agtr2 angiotensin II receptor, type 2
24185 Akt1 AKT serine/threonine kinase 1
24192 Akr1b1 aldo-keto reductase family 1 member B1
24221 Avp arginine vasopressin
24225 Bdnf brain-derived neurotrophic factor
24241 Calca calcitonin-related polypeptide alpha
24296 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
24310 Ace angiotensin I converting enzyme
Displaying entries 1 - 10 of 80 in total
Gene ID Gene Symbol Description Source
31234 Pdfr Pigment-dispersing factor receptor
31248 sgg shaggy
31271 w white
31806 Ogg1 8-oxoguanine DNA glycosylase
31926 Idgf4 Imaginal disc growth factor 4
32442 Rab3-GEF Rab3 GDP-GTP exchange factor
32974 Zw Zwischenferment
33007 Dop2R Dopamine 2-like receptor
33496 lilli lilliputian
34091 Spn28Dc Serpin 28Dc
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
30173 nog3 noggin 3
30174 nog1 noggin 1
30262 ins preproinsulin
30667 mtnr1aa melatonin receptor 1A a
30668 mtnr1bb melatonin receptor 1Bb
30682 vegfaa vascular endothelial growth factor Aa
266751 adra2b adrenoceptor alpha 2B
321664 aldob aldolase b, fructose-bisphosphate
337685 ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
393807 ppp1r3cb protein phosphatase 1, regulatory subunit 3Cb
Displaying entries 11 - 20 of 20 in total
Gene ID Gene Symbol Description Source Organism
407879 ppp1cc protein phosphatase 1, catalytic subunit, gamma isozyme Xenopus tropicalis (tropical clawed frog)
432039 pon2.S paraoxonase 2 S homeolog Xenopus laevis (African clawed frog)
432172 akt2.S v-akt murine thymoma viral oncogene homolog 2 S homeolog Xenopus laevis (African clawed frog)
448238 cadm2 cell adhesion molecule 2 Xenopus tropicalis (tropical clawed frog)
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
493191 nog noggin Xenopus tropicalis (tropical clawed frog)
553157 ogt O-linked N-acetylglucosamine (GlcNAc) transferase Xenopus tropicalis (tropical clawed frog)
100135191 ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100489505 ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 69 in total
Gene ID Gene Symbol Description Source
171619 C53D5.5 Gamma-glutamyltranspeptidase 1
171782 abt-2 ABC transporter domain-containing protein
171905 ace-2 Carboxylic ester hydrolase
171999 poml-2 Arylesterase
172085 ugt-26 UDP-glucuronosyltransferase
172509 gpdh-3 putative glycerol-3-phosphate dehydrogenase, mitochondrial
173297 F49B2.6 Aminopeptidase
174685 ptp-3 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase
175076 ace-3 Carboxylic ester hydrolase
175182 ver-1 Protein ver-1
Displaying entries 1 - 10 of 32 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850369 ADP1 putative ATP-dependent permease ADP1
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850614 HXK1 hexokinase 1
850645 BPT1 ATP-binding cassette bilirubin transporter BPT1
850678 YBT1 bile acid-transporting ATPase YBT1
850886 ATG26 sterol 3-beta-glucosyltransferase
850979 PIG1 protein phosphatase regulator PIG1
851006 ECM38 gamma-glutamyltransferase
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
The Human Phenotype Ontology
Displaying all 4 entries
HPO ID HPO Term
HP:0000855 Insulin resistance
HP:0005978 Type II diabetes mellitus
HP:0000006 Autosomal dominant inheritance
HP:0003584 Late onset
Displaying all 6 entries
Gene ID Gene Symbol Description
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
2820 GPD2 glycerol-3-phosphate dehydrogenase 2
6514 SLC2A2 solute carrier family 2 member 2
2645 GCK glucokinase
5506 PPP1R3A protein phosphatase 1 regulatory subunit 3A
3990 LIPC lipase C, hepatic type
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Acknowledgements

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024