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MIRAGE
type 1 diabetes mellitus
Summary
- Synonym
-
- IDDM
- insulin-dependent diabetes mellitus
- type I diabetes mellitus
- Definition
- A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
- Super Class
- autoimmune disease of endocrine system diabetes mellitus
External Links
- Disease Ontology
- DOID:9744
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- GARD
- MGI genotype (from TogoID)
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Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 177 | AGER | advanced glycosylation end-product specific receptor | |
| 217 | ALDH2 | aldehyde dehydrogenase 2 family member | |
| 345 | APOC3 | apolipoprotein C3 | |
| 590 | BCHE | butyrylcholinesterase | |
| 629 | CFB | complement factor B | |
| 685 | BTC | betacellulin | |
| 940 | CD28 | CD28 molecule | |
| 941 | CD80 | CD80 molecule | |
| 942 | CD86 | CD86 molecule | |
| 952 | CD38 | CD38 molecule |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24221 | Avp | arginine vasopressin | |
| 24464 | Hp | haptoglobin | |
| 25385 | Faslg | Fas ligand | |
| 25549 | Slc18a2 | solute carrier family 18 member A2 | |
| 25712 | Ifng | interferon gamma | |
| 84349 | Cd40lg | CD40 ligand | |
| 116660 | Ptprn | protein tyrosine phosphatase, receptor type, N |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| O15455 | Toll-like receptor 3 | |
| O60603 | Toll-like receptor 2 | |
| O76024 | Wolframin | |
| O95445 | Apolipoprotein M | |
| P00441 | Superoxide dismutase [Cu-Zn] | |
| P00751 | Complement factor B | |
| P01374 | Lymphotoxin-alpha | |
| P01375 | Tumor necrosis factor | |
| P01583 | Interleukin-1 alpha | |
| P01589 | Interleukin-2 receptor subunit alpha |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P59110 | Sentrin-specific protease 1 | |
| Q571D4 | MKIAA0387 protein (Fragment) | |
| Q63953 | Ifngr2 protein | |
| Q9Z186 | Glucose-6-phosphatase 2 |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P01186 | Vasopressin-neurophysin 2-copeptin | |
| P01581 | Interferon gamma | |
| P06759 | Apolipoprotein C-III | |
| P06866 | Haptoglobin | |
| P36940 | Tumor necrosis factor ligand superfamily member 6 | |
| Q01827 | Synaptic vesicular amine transporter | |
| Q63259 | Receptor-type tyrosine-protein phosphatase-like N | |
| Q9Z2V2 | CD40 ligand |
